Gene Details:

• MSU gene ID: LOC_Os06g29310
• RAPdb gene ID: Os06g0487900
• Gene Symbol: OsOTS1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• We demonstrate that OsOTS1 confers salt tolerance in rice by increasing root biomass.
• High salinity triggers OsOTS1 degradation indicating that increased SUMO conjugation in rice plants during salt stress is in part achieved by down-regulation of OTS1/2 activity.
• In this report, we reveal the Ubiquitin-like Protease (ULP) class of SUMO protease gene family in rice and demonstrate a critical role for OsOTS1 SUMO protease in salt stress.
• Transgenic rice plants overexpressing OsOTS1 have increased salt tolerance and a concomitant reduction in the levels of SUMOylated proteins.
• OsOTS1 is nuclear localised indicating a direct requirement of OsOTS1 dependent deSUMOylation activity in rice nuclei for salt tolerance.
• Knockdown of OsOTS1 gene expression affects root growth by primarily reducing cell size rather than cell division.
• We recently identified the SUMO protease gene family in rice and demonstrated a role for OsOTS1 SUMO proteases in salt stress.
• We reveal that OsOTS1 SUMO protease directly targets the ABA and drought responsive transcription factor OsbZIP23 for de-SUMOylation affecting its stability.
• In this study, we reveal the role of the SUMO protease, OsOTS1 in mediating tolerance to drought in rice.
• OsOTS1 depleted transgenic plants accumulate more ABA and exhibit more productive agronomic traits during drought whilst OsOTS1 overexpressing lines are drought sensitive but ABA insensitive.
• Drought and ABA treatment stimulates the degradation of OsOTS1 protein indicating that SUMO conjugation is an important response to drought stress in rice achieved through down-regulation of OTS1/2 activity.
• OsOTS-RNAi lines show increased abundance of OsbZIP23 and increased drought responsive gene expression while OsOTS1 overexpressing lines show reduced levels of OsbZIP23 leading to suppressed drought responsive gene expression.

Function-related keywords:

• root ,  salinity ,  salt ,  tolerance ,  salt-tolerance ,  salt-stress ,  stress ,  biomass ,  growth ,  cell-division ,  transcription-factor ,  drought ,  ABA ,  drought-stress

Literature:

• SUMO Is a Critical Regulator of Salt Stress Responses in Rice .  DOI:  10.1104/pp.15.01530 ;  PMID:  26869703
• Rice OVERLY TOLERANT TO SALT 1 (OTS1) SUMO protease is a positive regulator of seed germination and root development .  DOI:  10.1080/15592324.2016.1173301 ;  PMID:  27119209
• Rice SUMO protease Overly Tolerant to Salt 1 targets the transcription factor, OsbZIP23 to promote drought tolerance in rice .  DOI:  10.1111/tpj.13739 ;  PMID:  29024118

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: