Gene Details:

• MSU gene ID: LOC_Os05g51670
• RAPdb gene ID: Os05g0595100
• Gene Symbol: OsUGE1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• OsUGE1 is directly targeted by OsGRF6 to regulate root hair length in rice.
• Here, we report a novel mechanism that OsUGE1 is negatively controlled by OsGRF6 to regulate root hair elongation in rice.
• Knockout mutants of OsUGE1 using CRISPR-Cas9 technology showed longer root hairs than those of wild type.
• In contrast, overexpression lines of OsUGE1 displayed shorter root hair compared with those of wild type.
• Taken together, our study reveals a novel pathway that OsUGE1 is negatively controlled by OsGRF6 to regulate root hair elongation in rice.
• Subcellular localization analysis indicates that OsUGE1 is located in endoplasmic reticulum, nucleus and plasma membrane.
• Collectively, our results indicate that OsUGE1 not only functions as a UDP-glucose epimerase but also moonlights as a transcriptional activator to promote tapetum degradation, revealing a novel regulatory mechanism of rice reproductive development.
• Interestingly, we discovered that OsUGE1 participates in the TIP2/bHLH142-TDR-EAT1/DTD transcriptional regulatory cascade involved in tapetum degradation, in which TIP2 and TDR regulate the expression of OsUGE1 while OsUGE1 regulates the expression of EAT1.

Function-related keywords:

• root ,  nucleus ,  plasma-membrane ,  root-hair ,  development ,  tapetum ,  reproductive ,  reproductive-development ,  transcriptional-regulator ,  transcriptional-activator ,  tapetum-degradation

Literature:

• OsUGE1 is directly targeted by OsGRF6 to regulate root hair length in rice .  DOI:  10.1007/s00122-023-04356-4 ;  PMID:  37039968
• UDP-glucose epimerase 1, moonlighting as a transcriptional activator, is essential for tapetum degradation and male fertility in rice .  DOI:  10.1016/j.molp.2023.03.008 ;  PMID:  36926693

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: