Information report for OsMSH5
Gene Details
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Functional Descriptions
- The synaptonemal complex is well installed in OsMSH5, while the chiasma frequency is greatly reduced to approximately 10% of that observed in the wild-type, leading to the homologous non-disjunction and complete sterile phenotype.
- Immunofluorescence studies indicate that OsMSH5 chromosomal localization is limited to the early meiotic prophase I.
- OsMSH5 can be loaded onto meiotic chromosomes in Oszip4, Osmer3, and hei10.
- Here, we report the identification and characterization of its rice homolog, OsMSH5, and demonstrate its function in rice meiosis.
- The role of OsMSH5 in crossover formation during rice meiosis.
- OsMSH5 is predominantly expressed in panicles.
- Five independent OsMSH5 mutants exhibited normal vegetative growth and severe sterility.
- The MSH4-MSH5 heterodimer has been demonstrated in mammals to stabilize the formation of progenitor and double Holliday junctions that may be resolved as crossovers (COs).
- Crossover Formation During Rice Meiosis Relies on Interaction of OsMSH4 and OsMSH5.
Functional Keywords
- sterile , meiotic , meiosis , panicle , sterility , vegetative , growth , crossover , Holliday-junctions
Literature and News
Homologs
- Capsicum annuum: CA06g18030
Sequences
cDNA Sequence
- >LOC_Os05g41880.1
AACAACTTCCTTCCCGTACAAGCCAGTGCCCGAGCCACGCTCCCGCCGCACTTCGCCCCTCGCCGCCTAGCTTGCTCCATCCTCCGCGCCCGCGCAGCTGCGCTCGCCGTCGCCGTCGCTGCCTAGCTTCCTCCAGCCTCCGCATCTGCGCTCTATTTGTACCGCATTCTCGGAGGAGGAGCAGGAGGCGAGGAGCCGCCGAGTAGAGGAGAGGGGGAGGCGAAGTCGGTGCTCTCGCCGGGGGTTGACGGTGGAACTCCGGGCGAGCGATCGAGCCGGCGAAATGGACGAGGAAGAGGAGGAGGAGATGTCCGAGAGGGAGGTCGACTCCCAGGTTCATATGGCTTGTGTAATGCAAGGACGCAGAGTTGGAATAGCATACTATGATTCAAGTATGCACCAGCTTTTTGTATTGGAAATCTGGGAAGACATAACTGAAGATTTTCCTTTGATTGATCTTGTGAAATATCAATCCAAACCGAGCACAATATACACAAGTACTAAAACAGATGAGGCACTTTTGTTGGCGTTACAACGAAATGATTGTAATGATGAGGCCCCTGCTGTGAAGCTCATGAAAAGCTCAACCTTCAGCTATGAGCAAGCCTGGCACAGATTAATGTACTTGAAAGTCGCAGCTATGGACGAAGGGTTAAGTGTAAAAGAAAGGATCTGTTTTCTTAATTCCATGATGGATCTTGGAAGTGACGTTCAAGTTCGTGCTGCTGGAGGTCTTCTTGCTATATTAGACAACGAGAGGCTTCTTGATACCCTTGATCAGATGGAAGGTGGAGCATCCATTGCTATTGATTCTGTGGCACAGATATCATTTTATCCTTTTATCCGTAATGATATTATACGGACTAAATGTGCTAATGTACTGATCAGCATGTTTTTGTGGTTTTACTTTGGAAACAAGTTAGAAAGCTATTTATGTAGGATTGTAGTGCGTCACTCCTATGGGAAAACATCTCTTGAGGTCACTGTTACTTTCTATAATCATGATTGCAGATTTGCAAAATTCAACTCTCCAAGTTCATTCTGTACAAGCAGTGACTGGCATGCATTTCTGAAGTGCATTTGCTCTCTTCTGCATATAAACAAGATTTTTGAAGTAGGAATATCAGAGCATTTGGCAATCAAATTACAACATATGAACATTGACTTGGTTGGAAAGGCCAATTCTTCCATTACAGAAGAGCTGGATTATGTATCAGATCTGGTAGTTGGTGTGATTGATGTGCAACGGGGTAAAGAAAAAGGCTACGACACACTGGTGAAAGACGGATTATGTGAGGAGTTAGACGAACTGAGGATGGTCTATGAAGAATTGCCTGATTTTTTGGAGCAGGTGTCAGCCAATGAAATTGCCTCCTTCCCTTTCTCATTTGAATGCAGAAAAGCTCCTCTAATCGTCTATGTACACCAAATAGGATATTTAATGTGTTTTTTCGATGAGAAGATAAGTGATGCCTTGTTGATAGGACTTCCAGATTTTGAATTTGCGGAAATGACTGTTGATACCTTCGTTCCAAATGACACTAAAATCCGCAGTTCAGGACGAATCAACATAATAACTGGACCTAACTACTCAGGGAAAAGCATTTACATCAAGCAGGTGGCTTTGGTGGTTTTTCTTGCTCATATTGGAAGCTTTGTTCCTGCTGATTCTGCCATTGTTGGATTGACAGATAGGATTTTCTGTGCAATGGGCAGCAAATCCATGACAAGTGAACAGTCAACTTTTATGATTGATTTACATCAAGTTGGAACAATGCTCAGATGGTATTGGTCTGCTTGGAGGAACTATCAGCCATTTTACAGACTACGATTGTCCTCCAAAGGTGCTAGCTTGGAAAAATGTTGCTACTGA
CDS Sequence
- >LOC_Os05g41880.1
ATGGACGAGGAAGAGGAGGAGGAGATGTCCGAGAGGGAGGTCGACTCCCAGGTTCATATGGCTTGTGTAATGCAAGGACGCAGAGTTGGAATAGCATACTATGATTCAAGTATGCACCAGCTTTTTGTATTGGAAATCTGGGAAGACATAACTGAAGATTTTCCTTTGATTGATCTTGTGAAATATCAATCCAAACCGAGCACAATATACACAAGTACTAAAACAGATGAGGCACTTTTGTTGGCGTTACAACGAAATGATTGTAATGATGAGGCCCCTGCTGTGAAGCTCATGAAAAGCTCAACCTTCAGCTATGAGCAAGCCTGGCACAGATTAATGTACTTGAAAGTCGCAGCTATGGACGAAGGGTTAAGTGTAAAAGAAAGGATCTGTTTTCTTAATTCCATGATGGATCTTGGAAGTGACGTTCAAGTTCGTGCTGCTGGAGGTCTTCTTGCTATATTAGACAACGAGAGGCTTCTTGATACCCTTGATCAGATGGAAGGTGGAGCATCCATTGCTATTGATTCTGTGGCACAGATATCATTTTATCCTTTTATCCGTAATGATATTATACGGACTAAATGTGCTAATGTACTGATCAGCATGTTTTTGTGGTTTTACTTTGGAAACAAGTTAGAAAGCTATTTATGTAGGATTGTAGTGCGTCACTCCTATGGGAAAACATCTCTTGAGGTCACTGTTACTTTCTATAATCATGATTGCAGATTTGCAAAATTCAACTCTCCAAGTTCATTCTGTACAAGCAGTGACTGGCATGCATTTCTGAAGTGCATTTGCTCTCTTCTGCATATAAACAAGATTTTTGAAGTAGGAATATCAGAGCATTTGGCAATCAAATTACAACATATGAACATTGACTTGGTTGGAAAGGCCAATTCTTCCATTACAGAAGAGCTGGATTATGTATCAGATCTGGTAGTTGGTGTGATTGATGTGCAACGGGGTAAAGAAAAAGGCTACGACACACTGGTGAAAGACGGATTATGTGAGGAGTTAGACGAACTGAGGATGGTCTATGAAGAATTGCCTGATTTTTTGGAGCAGGTGTCAGCCAATGAAATTGCCTCCTTCCCTTTCTCATTTGAATGCAGAAAAGCTCCTCTAATCGTCTATGTACACCAAATAGGATATTTAATGTGTTTTTTCGATGAGAAGATAAGTGATGCCTTGTTGATAGGACTTCCAGATTTTGAATTTGCGGAAATGACTGTTGATACCTTCGTTCCAAATGACACTAAAATCCGCAGTTCAGGACGAATCAACATAATAACTGGACCTAACTACTCAGGGAAAAGCATTTACATCAAGCAGGTGGCTTTGGTGGTTTTTCTTGCTCATATTGGAAGCTTTGTTCCTGCTGATTCTGCCATTGTTGGATTGACAGATAGGATTTTCTGTGCAATGGGCAGCAAATCCATGACAAGTGAACAGTCAACTTTTATGATTGATTTACATCAAGTTGGAACAATGCTCAGATGGTATTGGTCTGCTTGGAGGAACTATCAGCCATTTTACAGACTACGATTGTCCTCCAAAGGTGCTAGCTTGGAAAAATGTTGCTACTGA
Protein Sequence
- >LOC_Os05g41880.1
MDEEEEEEMSEREVDSQVHMACVMQGRRVGIAYYDSSMHQLFVLEIWEDITEDFPLIDLVKYQSKPSTIYTSTKTDEALLLALQRNDCNDEAPAVKLMKSSTFSYEQAWHRLMYLKVAAMDEGLSVKERICFLNSMMDLGSDVQVRAAGGLLAILDNERLLDTLDQMEGGASIAIDSVAQISFYPFIRNDIIRTKCANVLISMFLWFYFGNKLESYLCRIVVRHSYGKTSLEVTVTFYNHDCRFAKFNSPSSFCTSSDWHAFLKCICSLLHINKIFEVGISEHLAIKLQHMNIDLVGKANSSITEELDYVSDLVVGVIDVQRGKEKGYDTLVKDGLCEELDELRMVYEELPDFLEQVSANEIASFPFSFECRKAPLIVYVHQIGYLMCFFDEKISDALLIGLPDFEFAEMTVDTFVPNDTKIRSSGRINIITGPNYSGKSIYIKQVALVVFLAHIGSFVPADSAIVGLTDRIFCAMGSKSMTSEQSTFMIDLHQVGTMLRWYWSAWRNYQPFYRLRLSSKGASLEKCCY*