Gene Details:

• MSU gene ID: LOC_Os05g34730
• RAPdb gene ID: Os05g0420300
• Gene Symbol: SERF1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Here, we characterize the role of the rice transcription factor (TF) SALT-RESPONSIVE ERF1 (SERF1) during grain development.
• Consistently, during grain filling, starch biosynthesis genes such as GRANULE-BOUND STARCH SYNTHASEI (GBSSI), STARCH SYNTHASEI (SSI), SSIIIa, and ADP-GLUCOSE PYROPHOSPHORYLASE LARGE SUBUNIT2 (AGPL2) are up-regulated in SERF1 knockout grains.
• In agreement, plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance.
• Here, we identified salt-responsive ERF1 (SERF1), a rice (Oryza sativa) transcription factor (TF) gene that shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment.
• Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs.
• We propose that SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress and translates the salt-induced signal into an appropriate expressional response resulting in salt tolerance.
• Through genome-wide expression profiling and chromatin immunoprecipitation, we found that SERF1 directly regulates RICE PROLAMIN-BOX BINDING FACTOR (RPBF), a TF that functions as a positive regulator of grain filling.
• Our study reveals that SERF1 represents a negative regulator of grain filling and seedling establishment by timing the expression of RPBF.
• Loss of SERF1 results in more rapid seedling establishment, while SERF1 overexpression has the opposite effect.
• Loss of SERF1 enhances RPBF expression resulting in larger grains with increased starch content, while SERF1 overexpression represses RPBF resulting in smaller grains.

Function-related keywords:

• salt ,  starch-biosynthesis ,  salinity ,  root ,  salt-tolerance ,  salt-stress ,  grain-filling ,  seedling ,  grain ,  transcription-factor ,  starch

Literature:

• SALT-RESPONSIVE ERF1 is a negative regulator of grain filling and gibberellin-mediated seedling establishment in rice .  DOI:  10.1093/mp/sst131 ;  PMID:  24046061
• Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice .  DOI:  10.1105/tpc.113.113068 ;  PMID:  23800963

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: