Gene Details:

• MSU gene ID: LOC_Os05g11950
• RAPdb gene ID: Os05g0210100
• Gene Symbol: MHZ11
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Our study reveals a previously unidentified mechanism by which MHZ11 participates in ethylene signaling for regulation of root growth in rice.
• The GDSL Lipase MHZ11 Modulates Ethylene Signaling in Rice Roots.
• Here, from analysis of an ethylene insensitive mutant MHZ11, we identified a GDSL lipase MHZ11 which modulates ethylene signaling in rice roots.
• MHZ11 overexpression caused constitutive ethylene response in roots.
• Genetically, MHZ11 acts at the ethylene receptor OsERS2 upstream of OsCTR2 and OsEIN2.
• MHZ11 mutation maintains more OsCTR2 in phosphorylated form whereas MHZ11 overexpression promotes ethylene inhibition of OsCTR2 phosphorylation.
• MHZ11 co-localized with the ethylene receptor OsERS2, and its effect on OsCTR2 phosphorylation requires ethylene perception and signaling initiation.
• Blocking sterol biosynthesis partially rescued MHZ11 ethylene response likely by reducing receptor-OsCTR2 interaction and OsCTR2 phosphorylation.
• We propose that MHZ11 works to reduce sterol level to impair receptor-OsCTR2 interaction and OsCTR2 phosphorylation for triggering of signaling upon ethylene treatment.

Function-related keywords:

• root ,  growth ,  ethylene ,  ethylene-response ,  root-growth

Literature:

• The GDSL Lipase MHZ11 Modulates Ethylene Signaling in Rice Roots .  DOI:  10.1105/tpc.19.00840 ;  PMID:  32184349

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: