Gene Details:
- MSU gene ID: LOC_Os05g11414
- RAPdb gene ID: Os05g0203800
- Gene Symbol: OSMADS58
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- By contrast, RNA-silenced lines of OSMADS58 develop astonishing flowers that reiterate a set of floral organs, including lodicules, stamens, and carpel-like organs, suggesting that determinacy of the floral meristem is severely affected.
- The transgenic rice expressing OSMADS58SRDX had reiterated formation of lodicule-like organs instead of stamens and carpel, a typical phenotype of ag mutant.
- Although the transgenic tall fescue did not have the stamen alterations seen in SPW1SRDX and OSMADS58SRDX rice, they either produced no pollen or produced immature pollen; thus, the anthers were not dehiscent and the plants were male-sterile.
- We first introduced Os12g0207000SRDX, Os01g0886200SRDX and OSMADS58SRDX into rice for evaluation of their abilities to induce male sterility.
- We also obtained a mild phenotype of OSMADS58SRDX tall fescue, which exhibited only the male sterility.
- Male-sterile and cleistogamous phenotypes in tall fescue induced by chimeric repressors of SUPERWOMAN1 and OSMADS58.
- Some lines of OSMADS58SRDX tall fescue showed a cleistogamous phenotype in which the lodicules were homeotically transformed into lemma-like organs.
- Furthermore, our results indicate important roles of OsMADS32 in defining stamen, pistil and ovule development through physical and genetic interactions with OsMADS1, OSMADS58 and OsMADS13, and in specifying floral meristem identity with OsMADS6, OsMADS3 and OSMADS58 respectively.
- Rice (Oryza sativa) OSMADS58 is a C-class MADS box protein, and characterization of a transposon insertion mutant OSMADS58 suggested that OSMADS58 plays a role in stamen development.
- This CRISPR mutant line exhibited stronger changes in expression of OSMADS58 target genes compared with the OSMADS58 dSpm (transposon insertion) line, along with changes in multiple pathways related to early stamen development.
- These findings strongly suggest that the pleiotropic effects of OSMADS58 on stamen development derive from a potential role in stabilizing gene regulatory circuits during early stamen development.
- Here, we report that the CRISPR knockout mutant OSMADS58 exhibits complex altered phenotypes, including anomalous diploid germ cells, aberrant meiosis, and delayed tapetum degeneration.
- OSMADS58 Stabilizes Gene Regulatory Circuits during Rice Stamen Development.
Function-related keywords:
- floral , stamen , pollen , sterility , flower , sterile , anther , meristem , lemma , floral-meristem , development , ovule , tapetum , tapetum-degeneration
Literature:
- Male-sterile and cleistogamous phenotypes in tall fescue induced by chimeric repressors of SUPERWOMAN1 and OsMADS58 . DOI: 10.1016/j.plantsci.2011.08.010 ; PMID: 22195592
- Functional analysis of all AGAMOUS subfamily members in rice reveals their roles in reproductive organ identity determination and meristem determinacy . DOI: 10.1105/tpc.111.087007 ; PMID: 21810995
- Functional diversification of the two C-class MADS box genes OSMADS3 and OSMADS58 in Oryza sativa . DOI: 10.1105/tpc.105.037200 ; PMID: 16326928
- Rice MADS6 interacts with the floral homeotic genes SUPERWOMAN1, MADS3, MADS58, MADS13, and DROOPING LEAF in specifying floral organ identities and meristem fate . DOI: 10.1105/tpc.111.087262 ; PMID: 21784949
- A Gene Expression Profiling of Early Rice Stamen Development that Reveals Inhibition of Photosynthetic Genes by OsMADS58 . DOI: 10.1016/j.molp.2015.02.004 ; PMID: 25684654
- Rice transcription factor MADS32 regulates floral patterning through interactions with multiple floral homeotic genes . DOI: 10.1093/jxb/eraa588 ; PMID: 33337484
- Characterization of a new rice OsMADS1 null mutant generated by homologous recombination-mediated gene targeting . DOI: 10.1007/s00425-020-03547-3 ; PMID: 33474591
- OsMADS58 Stabilizes Gene Regulatory Circuits during Rice Stamen Development . DOI: 10.3390/plants11212899 ; PMID: 36365352
Related News:
Gene Resources:
- NCBI ID: AB232157
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os05g11414.1
ACTCCATCTCATCTCATCCTTCCCCAACCATTCTCTTCTCCTTGAACACACCCCTCTCTTCCTCATTATAATCTCTTCTTTGATTAGAGAGGAATTAGCAAACATGCACATATACAAAGAGCAGGAGGCTGAACCATCCACTGGCCTGATGATGCCAGAGCCAGCACCTGTTGCTTCCCCCGGCTCCGGTGGCTCAGGTGGCTCAGGCTCGGTGGGAGCTGAGAAGATTGGGAGCAGGGGAAAGATTGAGATCAAGCGCATCGAGAACACGACGAACCGTCAAGTGACCTTCTGCAAGCGCCGCAGCGGGCTACTCAAGAAGGCGTATGAGCTCTCCGTGCTCTGCGATGCCGAGGTCGCCCTCGTCGTCTTCTCCAGCCGTGGCCGCCTCTACGAGTACTCCAACAACAGCGTGAAGGAAACTATTGAGAGGTACAAGAAAGCCAACAGTGACACCTCCAACGCCAGTACAGTTGCAGAGATCAATGCCCAGCACTACCAGCAGGAAGCTGCTAAGCTGAAGCAACAGATCACCAACCTGCAGAACTCCAACAGGACCCTAGTAGGTGATAATATCACCACCATGAACCACAGAGAACTTAAGCAGCTGGAAGGCAGACTGGACAAAGGCCTAGGAAAGATTAGAGCACGGAAGAACGAATTGCTGTGTGCTGAAATTGAGTATATGCAGAGAAGGGAAACGGAGCTGCAGAATGACAACATGTACTTAAAGAGCAAAGTTGCTGAGAGTGAAAGAGGACTGCAAACAGTGAACATGATGGGTTCAGCATCTACGAGCGAGTACGTGCAAAATATGATCCATTATGATCCAAGAAACTTCCTGCAATTCAACATCATGCATCAGCCTCAGTATTATCCTGAACAGGAGGACCGAAAGGCCTTTATGTCAGGTAAAAAATATTCTCAGTGTAACATAGTCAGAGTTCATAGTTCAACAAATGAAATTTGAATGTTCATTACCTTCTCATTGTAAGCATCTGAGTCGTAGTTAGAGACATCAAGTTTTTCAAAATAAAAAAATAAAAAATAATGAAGAGTTTTCTTGGGAGGATTATATTGCAGGGTCAGAAATGTGTAGGGCTTATCTCACATTCTAGGTATTGTTTGGATTTGCTTGCAACCATAAGAATTATAACTCAAATTTCCCTTGCATCAAATTATAGAAGGAATTCGGAGGCATAAGTTATAGACAAATAATGTGGTCGAGACAAGTTTGTGCAAGTACGTTCAGATGCAACGCGTAACTAATTTTGTT
CDS Sequence
- >LOC_Os05g11414.1
ATGCACATATACAAAGAGCAGGAGGCTGAACCATCCACTGGCCTGATGATGCCAGAGCCAGCACCTGTTGCTTCCCCCGGCTCCGGTGGCTCAGGTGGCTCAGGCTCGGTGGGAGCTGAGAAGATTGGGAGCAGGGGAAAGATTGAGATCAAGCGCATCGAGAACACGACGAACCGTCAAGTGACCTTCTGCAAGCGCCGCAGCGGGCTACTCAAGAAGGCGTATGAGCTCTCCGTGCTCTGCGATGCCGAGGTCGCCCTCGTCGTCTTCTCCAGCCGTGGCCGCCTCTACGAGTACTCCAACAACAGCGTGAAGGAAACTATTGAGAGGTACAAGAAAGCCAACAGTGACACCTCCAACGCCAGTACAGTTGCAGAGATCAATGCCCAGCACTACCAGCAGGAAGCTGCTAAGCTGAAGCAACAGATCACCAACCTGCAGAACTCCAACAGGACCCTAGTAGGTGATAATATCACCACCATGAACCACAGAGAACTTAAGCAGCTGGAAGGCAGACTGGACAAAGGCCTAGGAAAGATTAGAGCACGGAAGAACGAATTGCTGTGTGCTGAAATTGAGTATATGCAGAGAAGGGAAACGGAGCTGCAGAATGACAACATGTACTTAAAGAGCAAAGTTGCTGAGAGTGAAAGAGGACTGCAAACAGTGAACATGATGGGTTCAGCATCTACGAGCGAGTACGTGCAAAATATGATCCATTATGATCCAAGAAACTTCCTGCAATTCAACATCATGCATCAGCCTCAGTATTATCCTGAACAGGAGGACCGAAAGGCCTTTATGTCAGGTAAAAAATATTCTCAGTGTAACATAGTCAGAGTTCATAGTTCAACAAATGAAATTTGA
Protein Sequence
- >LOC_Os05g11414.1
MHIYKEQEAEPSTGLMMPEPAPVASPGSGGSGGSGSVGAEKIGSRGKIEIKRIENTTNRQVTFCKRRSGLLKKAYELSVLCDAEVALVVFSSRGRLYEYSNNSVKETIERYKKANSDTSNASTVAEINAQHYQQEAAKLKQQITNLQNSNRTLVGDNITTMNHRELKQLEGRLDKGLGKIRARKNELLCAEIEYMQRRETELQNDNMYLKSKVAESERGLQTVNMMGSASTSEYVQNMIHYDPRNFLQFNIMHQPQYYPEQEDRKAFMSGKKYSQCNIVRVHSSTNEI*