Gene Details:
- MSU gene ID: LOC_Os05g09020
- RAPdb gene ID: Os05g0183100
- Gene Symbol: OsWRKY67
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Overexpression of OsWRKY67 in rice confirmed enhanced disease resistance, but led to a restriction of plant growth in transgenic lines with high levels of OsWRKY67 protein.
- OsWRKY67 Plays a Positive Role in Basal and XA21-Mediated Resistance in Rice.
- Activation of OsWRKY67 by T-DNA tagging significantly improved the resistance against two rice pathogens, Magnaporthe oryzae and Xanthomonas oryzae pv.
- OsWRKY67 RNAi lines significantly reduced resistance to M.
- oryzae and Xoo isolates tested, and abolished XA21-mediated resistance, implying the possibility of broad-spectrum resistance from OsWRKY67.
- Therefore, these results suggest that OsWRKY67 positively regulates basal and XA21-mediated resistance, and is a promising candidate for genetic improvement of disease resistance in rice.
- Transcriptional activity and subcellular localization assays indicated that OsWRKY67 is present in the nucleus where it functions as a transcriptional activator.
- Reactive oxygen species (ROS) rapidly accumulated in OsWRKY67 activation mutant lines in response to elicitor treatment, compared with the controls.
- Here, we identified that the transcription of OsWRKY67 was strongly activated by leaf and panicle blast infection.
- Rice plants overexpressing OsWRKY67 showed quantitatively enhanced resistance to leaf blast, panicle blast and bacterial blight.
- These results together suggest the positive role of OsWRKY67 in regulating rice responses to leaf blast, panicle blast and bacterial blight disease.
- OsWRKY67 positively regulates blast and bacteria blight resistance by direct activation of PR genes in rice.
- RNA-seq analysis indicated that OsWRKY67 induces the transcription of a set of defense-related genes including the ones involved in the salicylic acid (SA)-dependent pathway.
- In contrast, silencing of OsWRKY67 increased the susceptibility to blast and bacterial blight diseases.
- OsWRKY67 is ubiquitously expressed and sub-localized in the nucleus.
Function-related keywords:
- growth , resistance , disease , disease-resistance , magnaporthe-oryzae , nucleus , xoo , transcriptional-activator , reactive-oxygen-species , plant-growth , leaf , panicle , salicylic-acid , blast , blight , bacterial-blight , blight-disease
Literature:
- OsWRKY67 Plays a Positive Role in Basal and XA21-Mediated Resistance in Rice . DOI: 10.3389/fpls.2017.02220 ; PMID: 29375598
- OsWRKY67 positively regulates blast and bacteria blight resistance by direct activation of PR genes in rice . DOI: 10.1186/s12870-018-1479-y ; PMID: 30367631
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os05g09020.1
ATCCATTACCATCACAGAAGAAAATTCACCGGTGAAAAGGTTCAGCACTGTGCAATGGCGGCTTCCGTAGGACTGAACCCTGAAGCTTTCTTCTTCAGCAACTCCTACTCCTACTCCTCATCCCCTTTCATGGCCAGCTACACGCCGGAGTTCTCGGCCGCCGCTATCGACGCCAACTTATTCTCCGGCGAGCTCGATTTCGACTGCTCTCTCCCAGCTCCGGCCCAGGAGTACCCGGAAAATGAAAACACTATGATGAGGTACGAGAGCGAGGAGAAGATGAGGGCGAGGGTGAACGGGAGGATCGGGTTCAGGACGAGGTCGGAGGTGGAGATTCTTGATGATGGCTTCAAGTGGAGGAAGTACGGCAAGAAAGCTGTCAAGAACAGCCCAAATCCAAGAAACTACTACCGGTGCTCGACGGAGGGGTGCAACGTGAAGAAGCGAGTGGAGAGAGACCGGGAGGACCACCGCTACGTCATCACCACCTACGACGGCGTCCACAACCACGCGAGCCCCGCCGCCGCCGCCGCGGCGCTGCAGTACGCCGCCGCCGCCGGCGACTACTACAGCCCGCCGCTCAGCAGCGCCGGCTCGCCGCCGGCCGCCTATTCGGCAGGCGGCTCGCTGCTCTTCTGAGGCTGATGAGTTTGTCTAGTACTAGACACGCCCGGGAGCTCTAGCTAGGATAGAAAACTAGAGAAAGTTTAATTATACCTGAATTTTAATTAATCACCTCACAAAACTCTGATGTATCATATTATATCGTGATAGTGACTGCTTGTTAATTTAATTTTGCCGATCGATGTGATCTTCGGTTCGTGTGTTCATGACTTAACGTCTTCATGTATGTTTTTAGCAGAAAGATCAACTGCTGGTTTTAATATACA - >LOC_Os05g09020.2
ATCCATTACCATCACAGAAGAAAATTCACCGGTGAAAAGGTTCAGCACTGTGCAATGGCGGCTTCCGTAGGACTGAACCCTGAAGCTTTCTTCTTCAGCAACTCCTACTCCTACTCCTCATCCCCTTTCATGGCCAGCTACACGCCGGAGTTCTCGGCCGCCGCTATCGACGCCAACTTATTCTCCGGCGAGCTCGATTTCGACTGCTCTCTCCCAGCTCCGGCCCAGGAGTACCCGGAAAATGAAAACACTATGATGAGGTACGAGAGCGAGGAGAAGATGAGGGCGAGGGTGAACGGGAGGATCGGGTTCAGGACGAGGTCGGAGGTGGAGATTCTTGATGATGGCTTCAAGTGGAGGAAGTACGGCAAGAAAGCTGTCAAGAACAGCCCAAATCCAAGAAACTACTACCGGTGCTCGACGGAGGGGTGCAACGTGAAGAAGCGAGTGGAGAGAGACCGGGAGGACCACCGCTACGTCATCACCACCTACGACGGCGTCCACAACCACGCGAGCCCCGCCGCCGCCGCCGCGGCGCTGCAGTACGCCGCCGCCGCCGGCGACTACTACAGCCCGCCGCTCAGCAGCGCCGGCTCGCCGCCGGCCGCCTATTCGGCAGGCGGCTCGCTGCTCTTCTGAGGCTGATGAGTTTGTCTAGTACTAGACACGCCCGGGAGCTCTAGCTAGGATAGAAAACTAGAGAAAGTTTAATTATACCTGAATTTTAATTAATCACCTCACAAAACTCTGATGTATCATATTATATCGTGATAGTGACTGCTTGTTAATTTAATTTTGCCGATCGATGTGATCTTCGGTTCGTGTGTTCATGACTTAACGTCTTCATGTATGTTTTTAGCAGAAAGATCAACTGCTGGTTTTAATATACA
CDS Sequence
- >LOC_Os05g09020.1
ATGGCGGCTTCCGTAGGACTGAACCCTGAAGCTTTCTTCTTCAGCAACTCCTACTCCTACTCCTCATCCCCTTTCATGGCCAGCTACACGCCGGAGTTCTCGGCCGCCGCTATCGACGCCAACTTATTCTCCGGCGAGCTCGATTTCGACTGCTCTCTCCCAGCTCCGGCCCAGGAGTACCCGGAAAATGAAAACACTATGATGAGGTACGAGAGCGAGGAGAAGATGAGGGCGAGGGTGAACGGGAGGATCGGGTTCAGGACGAGGTCGGAGGTGGAGATTCTTGATGATGGCTTCAAGTGGAGGAAGTACGGCAAGAAAGCTGTCAAGAACAGCCCAAATCCAAGAAACTACTACCGGTGCTCGACGGAGGGGTGCAACGTGAAGAAGCGAGTGGAGAGAGACCGGGAGGACCACCGCTACGTCATCACCACCTACGACGGCGTCCACAACCACGCGAGCCCCGCCGCCGCCGCCGCGGCGCTGCAGTACGCCGCCGCCGCCGGCGACTACTACAGCCCGCCGCTCAGCAGCGCCGGCTCGCCGCCGGCCGCCTATTCGGCAGGCGGCTCGCTGCTCTTCTGA - >LOC_Os05g09020.2
ATGGCGGCTTCCGTAGGACTGAACCCTGAAGCTTTCTTCTTCAGCAACTCCTACTCCTACTCCTCATCCCCTTTCATGGCCAGCTACACGCCGGAGTTCTCGGCCGCCGCTATCGACGCCAACTTATTCTCCGGCGAGCTCGATTTCGACTGCTCTCTCCCAGCTCCGGCCCAGGAGTACCCGGAAAATGAAAACACTATGATGAGGTACGAGAGCGAGGAGAAGATGAGGGCGAGGGTGAACGGGAGGATCGGGTTCAGGACGAGGTCGGAGGTGGAGATTCTTGATGATGGCTTCAAGTGGAGGAAGTACGGCAAGAAAGCTGTCAAGAACAGCCCAAATCCAAGAAACTACTACCGGTGCTCGACGGAGGGGTGCAACGTGAAGAAGCGAGTGGAGAGAGACCGGGAGGACCACCGCTACGTCATCACCACCTACGACGGCGTCCACAACCACGCGAGCCCCGCCGCCGCCGCCGCGGCGCTGCAGTACGCCGCCGCCGCCGGCGACTACTACAGCCCGCCGCTCAGCAGCGCCGGCTCGCCGCCGGCCGCCTATTCGGCAGGCGGCTCGCTGCTCTTCTGA
Protein Sequence
- >LOC_Os05g09020.1
MAASVGLNPEAFFFSNSYSYSSSPFMASYTPEFSAAAIDANLFSGELDFDCSLPAPAQEYPENENTMMRYESEEKMRARVNGRIGFRTRSEVEILDDGFKWRKYGKKAVKNSPNPRNYYRCSTEGCNVKKRVERDREDHRYVITTYDGVHNHASPAAAAAALQYAAAAGDYYSPPLSSAGSPPAAYSAGGSLLF* - >LOC_Os05g09020.2
MAASVGLNPEAFFFSNSYSYSSSPFMASYTPEFSAAAIDANLFSGELDFDCSLPAPAQEYPENENTMMRYESEEKMRARVNGRIGFRTRSEVEILDDGFKWRKYGKKAVKNSPNPRNYYRCSTEGCNVKKRVERDREDHRYVITTYDGVHNHASPAAAAAALQYAAAAGDYYSPPLSSAGSPPAAYSAGGSLLF*