Gene Details:
- MSU gene ID: LOC_Os05g06660
- RAPdb gene ID: Os05g0158500
- Gene Symbol: GS5
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- We showed that the quantitative trait locus (QTL) GS5 in rice controls grain size by regulating grain width, filling and weight.
- GS5 encodes a putative serine carboxypeptidase and functions as a positive regulator of grain size, such that higher expression of GS5 is correlated with larger grain size.
- The results suggest that natural variation in GS5 contributes to grain size diversity in rice and may be useful in improving yield in rice and, potentially, other crops(2).
- Natural variation in GS5 plays an important role in regulating grain size and yield in rice.
- Differential expression of GS5 regulates grain size in rice.
- GS5 is a positive regulator of grain size such that grain width, filling, and weight are correlated with its expression level.
- Previous work suggested that polymorphisms of GS5 in the promoter region might be responsible for the variation in grain size.
- Enhanced expression of GS5 competitively inhibits the interaction between OsBAK1-7 and OsMSBP1 by occupying the extracellular leucine-rich repeat (LRR) domain of OsBAK1-7, thus preventing OsBAK1-7 from endocytosis caused by interacting with OsMSBP1, providing an explanation for the positive association between grain size and GS5 expression.
- These results advanced our understanding of the molecular mechanism by which GS5 controls grain size.
- These two polymorphs altered the responses of the GS5 alleles to abscisic acid (ABA) treatments, resulting in higher expression of GS5-1 than of GS5-2 in developing young panicles.
Function-related keywords:
- grain-width , grain-size , grain , yield , abscisic-acid
Literature:
- Natural variation in GS5 plays an important role in regulating grain size and yield in rice . DOI: 10.1038/ng.977 ; PMID: 22019783
- Differential expression of GS5 regulates grain size in rice . DOI: 10.1093/jxb/erv058 ; PMID: 25711711
- Bin-based genome-wide association studies reveal superior alleles for improvement of appearance quality using a 4-way MAGIC population in rice . DOI: 10.1016/j.jare.2020.08.001 ; PMID: 33364055
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os05g06660.1
AAGAACACCAAACGAGAAGCTCCAAGCTCGCAATAATTCACCAAGAATCGCACCACTTTTCACCTTTTCTTCTCCTCCTCCATTTCCATCCATGGCGACGCTGCTGCTGCTGCTGCACACGGCGCAACAGTGAGCTATAGCTAGAGCTCGGCACCACGGGTTAGCAATGGCGGTGGCGGCGGCGGCGGCGGCGAGGCGGCGAGATGTCTCTTGTCTTCTCCTCCTCCTGTGCTTCAGCTCGTCAATGGCGGCGACCGGCGGCGGCGGCGGCGGCGGCGAGCAGGAGGCTGACAGGGTGGCGCGGCTCCCGGGGCAGCCGGCGAGCCCCGCCGTGTCGCAGTTCGCCGGCTACGTCGGCGTCGACGAGCGGCACGGCAGGGCGCTGTTCTACTGGTTCTTCGAGGCGCAGGCGTCGCCGGCGCCGGAGAAGAAGCCGCTGCTCCTCTGGCTCAATGGAGGACCTGGTTGCTCTTCCATTGGCTATGGTGCTGCATCAGAGCTAGGGCCTCTCAGAGTTGCAAGACAAGGAGCAGCACTAGAGTTCAACCAGTATGGCTGGAACAAAGAGGCTAACCTCCTGTTCTTGGAGTCTCCTGTTGGGGTCGGCTTCTCCTACACCAACACATCCTCTGACCTCTCCAATCTTAATGATGATTTTGTAGCTGAGGATGCTTATAGTTTCCTGGTGAACTGGTTCAAGAGATTTCCTCAGTACAAGGACAATGAGTTCTACATCTCAGGGGAGAGCTATGCAGGTCACTATGTGCCCCAACTTGCTGACCTTGTCTATGAGAGGAACAAAGACAAAAGGGCCAGCACATATATCAACCTCAAGGGGTTCATTGTAGGCAACCCTCTCACCGATGATTACTATGATTCAAAAGGTTTGGCTGAGTATGCCTGGAGCCATGCAATTGTGTCGGATCAAGTTTACGAGCGCATCAAGAAAACTTGCAACTTCAAGAACTCCAACTGGACTGACGATTGCAATGCTGCAATGAACATAATCTTCAGTCAGTACAATCAGATAGATATATACAACATTTATGCCCCAAAGTGCCTTCTAAACAGTACTTCAGCATCTTCACCTGATCGTGCATTCTTCGCAAATAACCAGGAACAATTCAGGTGGAGAATCAAGATGTTTTCAGGCTATGATCCATGCTACTCATCCTATGCTGAGGACTACTTCAATAAGCATGATGTGCAAGAAGCATTCCATGCAAATGCCAGTGGACTGCTTCCAGGGAAGTGGCAAGTTTGCAGTGACCAAATCCTCAACTCTTACAATTTCTCAGTACTTTCCATCCTACCTATATACTCCAAGCTCATCAAAGCAGGGCTGAGAGTTTGGCTCTACAGCGGTGATGCTGACGGCAGGGTCCCGGTTATCAGTTCTCGGTACTGCGTGGAAGCACTCGGCCTACCGATCAAGACCGATTGGCAATCTTGGTACCTTGACAAGCAGGTTGCTGGGAGGTTTGTGGAGTACCATGGAATGACAATGGTGACTGTCAGAGGGGCAGGTCACCTGGTTCCCCTCAACAAACCTGCTGAAGGGCTTATGCTGATAAATGCATTCCTTCATGGTGAGAAGCTTCCGACAAGCAGATGATATGCGCTGCTGATGAAGCTTTGGAGGTACAAGATGGCATGAGATACAGGCATGGACATCAATTTTCATTGAAAGGCGCCAATCGGATAGATTTGATATGGTAGTATCCAAATCAATTTCAAGTGCGCCGTAAATTCAGTACTCTGTTGAACATTCTTTTAAATCTGTTGTTGACTATGACTTTCTTCTTTTGTGTTTTTTTTACTCACCTTTTCCATATTATAAGTCGTTTTGGGTTTGTCCTATAATCAAACTTTTTAAGTCTGACAGTTTATAGAAAAATAAAGTAACATTTTCAACA - >LOC_Os05g06660.2
AAGAACACCAAACGAGAAGCTCCAAGCTCGCAATAATTCACCAAGAATCGCACCACTTTTCACCTTTTCTTCTCCTCCTCCATTTCCATCCATGGCGACGCTGCTGCTGCTGCTGCACACGGCGCAACAGTGAGCTATAGCTAGAGCTCGGCACCACGGGTTAGCAATGGCGGTGGCGGCGGCGGCGGCGGCGAGGCGGCGAGATGTCTCTTGTCTTCTCCTCCTCCTGTGCTTCAGCTCGTCAATGGCGGCGACCGGCGGCGGCGGCGGCGGCGGCGAGCAGGAGGCTGACAGGGTGGCGCGGCTCCCGGGGCAGCCGGCGAGCCCCGCCGTGTCGCAGTTCGCCGGCTACGTCGGCGTCGACGAGCGGCACGGCAGGGCGCTGTTCTACTGGTTCTTCGAGGCGCAGGCGTCGCCGGCGCCGGAGAAGAAGCCGCTGCTCCTCTGGCTCAATGGAGGACCTGGTTGCTCTTCCATTGGCTATGGTGCTGCATCAGAGCTAGGGCCTCTCAGAGTTGCAAGACAAGGAGCAGCACTAGAGTTCAACCAGTATGGCTGGAACAAAGAGGCTAACCTCCTGTTCTTGGAGTCTCCTGTTGGGGTCGGCTTCTCCTACACCAACACATCCTCTGACCTCTCCAATCTTAATGATGATTTTGTAGCTGAGGATGCTTATAGTTTCCTGGTGAACTGGTTCAAGAGATTTCCTCAGTACAAGGACAATGAGTTCTACATCTCAGGGGAGAGCTATGCAGGTCACTATGTGCCCCAACTTGCTGACCTTGTCTATGAGAGGAACAAAGACAAAAGGGCCAGCACATATATCAACCTCAAGGGGTTCATTGTAGGCAACCCTCTCACCGATGATTACTATGATTCAAAAGGTTTGGCTGAGTATGCCTGGAGCCATGCAATTGTGTCGGATCAAGTTTACGAGCGCATCAAGAAAACTTGCAACTTCAAGAACTCCAACTGGACTGACGATTGCAATGCTGCAATGAACATAATCTTCAGTCAGTACAATCAGATAGATATATACAACATTTATGCCCCAAAGTGCCTTCTAAACAGTACTTCAGCATCTTCACCTGATCGTGCATTCTTCGCAAATAACCAGGAACAATTCAGGTGGAGAATCAAGATGTTTTCAGGCTATGATCCATGCTACTCATCCTATGCTGAGGACTACTTCAATAAGCATGATGTGCAAGAAGCATTCCATGCAAATGCCAGTGGACTGCTTCCAGGGAAGTGGCAAGTTTGCAGTGACCAAATCCTCAACTCTTACAATTTCTCAGTACTTTCCATCCTACCTATATACTCCAAGCTCATCAAAGCAGGGCTGAGAGTTTGGCTCTACAGCGGTGATGCTGACGGCAGGGTCCCGGTTATCAGTTCTCGGTACTGCGTGGAAGCACTCGGCCTACCGATCAAGACCGATTGGCAATCTTGGTACCTTGACAAGCAGGTTGCTGGGAGGTTTGTGGAGTACCATGGAATGACAATGGTGACTGTCAGAGGGGCAGGTCACCTGGTTCCCCTCAACAAACCTGCTGAAGGGCTTATGCTGATAAATGCATTCCTTCATGGTGAGAAGCTTCCGACAAGCAGATGATATGCGCTGCTGATGAAGCTTTGGAGGTACAAGATGGCATGAGATACAGGCATGGACATCAATTTTCATTGAAAGGCGCCAATCGGATAGATTTGATATGGTAGTATCCAAATCAATTTCAAGTGCGCCGTAAATTCAGTACTCTGTTGAACATTCTTTTAAATCTGTTGTTGACTATGACTTTCTTCTTTTGTGTTTTTTTTACTCACCTTTTCCATATTATAAGTCGTTTTGGGTTTGTCCTATAATCAAACTTTTTAAGTCTGACAGTTTATAGAAAAATAAAGTAACATTTTCAACA
CDS Sequence
- >LOC_Os05g06660.1
ATGGCGGTGGCGGCGGCGGCGGCGGCGAGGCGGCGAGATGTCTCTTGTCTTCTCCTCCTCCTGTGCTTCAGCTCGTCAATGGCGGCGACCGGCGGCGGCGGCGGCGGCGGCGAGCAGGAGGCTGACAGGGTGGCGCGGCTCCCGGGGCAGCCGGCGAGCCCCGCCGTGTCGCAGTTCGCCGGCTACGTCGGCGTCGACGAGCGGCACGGCAGGGCGCTGTTCTACTGGTTCTTCGAGGCGCAGGCGTCGCCGGCGCCGGAGAAGAAGCCGCTGCTCCTCTGGCTCAATGGAGGACCTGGTTGCTCTTCCATTGGCTATGGTGCTGCATCAGAGCTAGGGCCTCTCAGAGTTGCAAGACAAGGAGCAGCACTAGAGTTCAACCAGTATGGCTGGAACAAAGAGGCTAACCTCCTGTTCTTGGAGTCTCCTGTTGGGGTCGGCTTCTCCTACACCAACACATCCTCTGACCTCTCCAATCTTAATGATGATTTTGTAGCTGAGGATGCTTATAGTTTCCTGGTGAACTGGTTCAAGAGATTTCCTCAGTACAAGGACAATGAGTTCTACATCTCAGGGGAGAGCTATGCAGGTCACTATGTGCCCCAACTTGCTGACCTTGTCTATGAGAGGAACAAAGACAAAAGGGCCAGCACATATATCAACCTCAAGGGGTTCATTGTAGGCAACCCTCTCACCGATGATTACTATGATTCAAAAGGTTTGGCTGAGTATGCCTGGAGCCATGCAATTGTGTCGGATCAAGTTTACGAGCGCATCAAGAAAACTTGCAACTTCAAGAACTCCAACTGGACTGACGATTGCAATGCTGCAATGAACATAATCTTCAGTCAGTACAATCAGATAGATATATACAACATTTATGCCCCAAAGTGCCTTCTAAACAGTACTTCAGCATCTTCACCTGATCGTGCATTCTTCGCAAATAACCAGGAACAATTCAGGTGGAGAATCAAGATGTTTTCAGGCTATGATCCATGCTACTCATCCTATGCTGAGGACTACTTCAATAAGCATGATGTGCAAGAAGCATTCCATGCAAATGCCAGTGGACTGCTTCCAGGGAAGTGGCAAGTTTGCAGTGACCAAATCCTCAACTCTTACAATTTCTCAGTACTTTCCATCCTACCTATATACTCCAAGCTCATCAAAGCAGGGCTGAGAGTTTGGCTCTACAGCGGTGATGCTGACGGCAGGGTCCCGGTTATCAGTTCTCGGTACTGCGTGGAAGCACTCGGCCTACCGATCAAGACCGATTGGCAATCTTGGTACCTTGACAAGCAGGTTGCTGGGAGGTTTGTGGAGTACCATGGAATGACAATGGTGACTGTCAGAGGGGCAGGTCACCTGGTTCCCCTCAACAAACCTGCTGAAGGGCTTATGCTGATAAATGCATTCCTTCATGGTGAGAAGCTTCCGACAAGCAGATGA - >LOC_Os05g06660.2
ATGGCGGTGGCGGCGGCGGCGGCGGCGAGGCGGCGAGATGTCTCTTGTCTTCTCCTCCTCCTGTGCTTCAGCTCGTCAATGGCGGCGACCGGCGGCGGCGGCGGCGGCGGCGAGCAGGAGGCTGACAGGGTGGCGCGGCTCCCGGGGCAGCCGGCGAGCCCCGCCGTGTCGCAGTTCGCCGGCTACGTCGGCGTCGACGAGCGGCACGGCAGGGCGCTGTTCTACTGGTTCTTCGAGGCGCAGGCGTCGCCGGCGCCGGAGAAGAAGCCGCTGCTCCTCTGGCTCAATGGAGGACCTGGTTGCTCTTCCATTGGCTATGGTGCTGCATCAGAGCTAGGGCCTCTCAGAGTTGCAAGACAAGGAGCAGCACTAGAGTTCAACCAGTATGGCTGGAACAAAGAGGCTAACCTCCTGTTCTTGGAGTCTCCTGTTGGGGTCGGCTTCTCCTACACCAACACATCCTCTGACCTCTCCAATCTTAATGATGATTTTGTAGCTGAGGATGCTTATAGTTTCCTGGTGAACTGGTTCAAGAGATTTCCTCAGTACAAGGACAATGAGTTCTACATCTCAGGGGAGAGCTATGCAGGTCACTATGTGCCCCAACTTGCTGACCTTGTCTATGAGAGGAACAAAGACAAAAGGGCCAGCACATATATCAACCTCAAGGGGTTCATTGTAGGCAACCCTCTCACCGATGATTACTATGATTCAAAAGGTTTGGCTGAGTATGCCTGGAGCCATGCAATTGTGTCGGATCAAGTTTACGAGCGCATCAAGAAAACTTGCAACTTCAAGAACTCCAACTGGACTGACGATTGCAATGCTGCAATGAACATAATCTTCAGTCAGTACAATCAGATAGATATATACAACATTTATGCCCCAAAGTGCCTTCTAAACAGTACTTCAGCATCTTCACCTGATCGTGCATTCTTCGCAAATAACCAGGAACAATTCAGGTGGAGAATCAAGATGTTTTCAGGCTATGATCCATGCTACTCATCCTATGCTGAGGACTACTTCAATAAGCATGATGTGCAAGAAGCATTCCATGCAAATGCCAGTGGACTGCTTCCAGGGAAGTGGCAAGTTTGCAGTGACCAAATCCTCAACTCTTACAATTTCTCAGTACTTTCCATCCTACCTATATACTCCAAGCTCATCAAAGCAGGGCTGAGAGTTTGGCTCTACAGCGGTGATGCTGACGGCAGGGTCCCGGTTATCAGTTCTCGGTACTGCGTGGAAGCACTCGGCCTACCGATCAAGACCGATTGGCAATCTTGGTACCTTGACAAGCAGGTTGCTGGGAGGTTTGTGGAGTACCATGGAATGACAATGGTGACTGTCAGAGGGGCAGGTCACCTGGTTCCCCTCAACAAACCTGCTGAAGGGCTTATGCTGATAAATGCATTCCTTCATGGTGAGAAGCTTCCGACAAGCAGATGA
Protein Sequence
- >LOC_Os05g06660.1
MAVAAAAAARRRDVSCLLLLLCFSSSMAATGGGGGGGEQEADRVARLPGQPASPAVSQFAGYVGVDERHGRALFYWFFEAQASPAPEKKPLLLWLNGGPGCSSIGYGAASELGPLRVARQGAALEFNQYGWNKEANLLFLESPVGVGFSYTNTSSDLSNLNDDFVAEDAYSFLVNWFKRFPQYKDNEFYISGESYAGHYVPQLADLVYERNKDKRASTYINLKGFIVGNPLTDDYYDSKGLAEYAWSHAIVSDQVYERIKKTCNFKNSNWTDDCNAAMNIIFSQYNQIDIYNIYAPKCLLNSTSASSPDRAFFANNQEQFRWRIKMFSGYDPCYSSYAEDYFNKHDVQEAFHANASGLLPGKWQVCSDQILNSYNFSVLSILPIYSKLIKAGLRVWLYSGDADGRVPVISSRYCVEALGLPIKTDWQSWYLDKQVAGRFVEYHGMTMVTVRGAGHLVPLNKPAEGLMLINAFLHGEKLPTSR* - >LOC_Os05g06660.2
MAVAAAAAARRRDVSCLLLLLCFSSSMAATGGGGGGGEQEADRVARLPGQPASPAVSQFAGYVGVDERHGRALFYWFFEAQASPAPEKKPLLLWLNGGPGCSSIGYGAASELGPLRVARQGAALEFNQYGWNKEANLLFLESPVGVGFSYTNTSSDLSNLNDDFVAEDAYSFLVNWFKRFPQYKDNEFYISGESYAGHYVPQLADLVYERNKDKRASTYINLKGFIVGNPLTDDYYDSKGLAEYAWSHAIVSDQVYERIKKTCNFKNSNWTDDCNAAMNIIFSQYNQIDIYNIYAPKCLLNSTSASSPDRAFFANNQEQFRWRIKMFSGYDPCYSSYAEDYFNKHDVQEAFHANASGLLPGKWQVCSDQILNSYNFSVLSILPIYSKLIKAGLRVWLYSGDADGRVPVISSRYCVEALGLPIKTDWQSWYLDKQVAGRFVEYHGMTMVTVRGAGHLVPLNKPAEGLMLINAFLHGEKLPTSR*