Gene Details:

• MSU gene ID: LOC_Os04g56480
• RAPdb gene ID: Os04g0659900
• Gene Symbol: OsPELOTA LML1 Ospelo
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• A substitution mutation in OsPELOTA confers bacterial blight resistance by activating the salicylic acid pathway.
• Here, we report the map-based cloning of the causal gene OsPELOTA (originally termed splHM47 ).
• LML1 is expressed in all types of leaf cells, and encodes a novel eukaryotic release factor 1 (eRF1) protein located in the endoplasmic reticulum (ER).
• LML1 can partially rescue the growth delay phenotype of the LML1 yeast ortholog mutant, dom34.
• Both LML1 and mutants of AtLML1 (the LML1 Arabidopsis ortholog) exhibited a growth delay phenotype as dom34.
• The LML1 mutant exhibited abnormal cell death and resistance to both bacterial blight and rice blast.
• The Ospelo mutant showed defects in root system development and spotted leaves at early seedling stages.
• These results demonstrate that Ospelo positively regulates root development while its loss of function enhances pathogen resistance by pre-activation of defence responses in rice.
• Defence responses were induced in the Ospelo mutant, as shown by enhanced resistance to the bacterial pathogen Xanthomonas oryzae pv.
• Detailed analysis showed that activation of a number of innate immunity-related genes might be responsible for the enhanced disease resistance in the Ospelo mutant.
• Ospelo was found to be expressed in various tissues throughout the plant, and the protein was located in mitochondria.
• In addition, whole-genome transcriptome analysis showed that Ospelo was significantly associated with a number of biological processes, including translation, metabolism and biotic stress response.

Function-related keywords:

• resistance ,  map-based-cloning ,  salicylic-acid ,  blight ,  bacterial-blight ,  leaf ,  growth ,  blast ,  cell-death ,  root ,  seedling ,  development ,  mitochondria ,  root-development ,  disease ,  disease-resistance ,  stress ,  biotic-stress ,  innate-immunity ,  pathogen ,  stress-response ,  defence ,  defence-response ,  pathogen-resistance

Literature:

• A substitution mutation in OsPELOTA confers bacterial blight resistance by activating the salicylic acid pathway .  DOI:  10.1111/jipb.12613 ;  PMID:  29193778
• LML1, Encoding a Conserved Eukaryotic Release Factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice .  DOI:  10.1093/pcp/pcy056 ;  PMID:  29566164
• A Pelota-like gene regulates root development and defence responses in rice .  DOI:  10.1093/aob/mcy075 ;  PMID:  29771278

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: