Gene Details:
- MSU gene ID: LOC_Os04g52540
- RAPdb gene ID: Os04g0615700
- Gene Symbol: OsAGO2
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Knockdown of OsAGO2 led to the overaccumulation of reactive oxygen species (ROS) and abnormal anther development, causing premature initiation of tapetal programmed cell death (PCD) and pollen abortion.
- Moreover, knockdown of OsHXK1 restored pollen fertility in OsAGO2 knockdown plants.
- Here, we show that the AGO protein OsAGO2 regulates anther development in rice.
- OsAGO2 controls ROS production and the initiation of tapetal PCD by epigenetically regulating OsHXK1 expression in rice anthers.
- These results indicate that OsHXK1 controls the appropriate production of ROS and the proper timing of tapetal PCD and is directly regulated by OsAGO2 through epigenetic regulation.
- Our results indicate that OsAGO2 is a key immune player that manipulates rice defense responses against blast disease.
Function-related keywords:
- pollen , anther , development , cell-death , fertility , tapetal , anther-development , PCD , reactive-oxygen-species , tapetal-programmed-cell-death , disease , defense-response , defense , blast , blast-disease
Literature:
- OsAGO2 controls ROS production and the initiation of tapetal PCD by epigenetically regulating OsHXK1 expression in rice anthers . DOI: 10.1073/pnas.1817675116 ; PMID: 30902896
- ARGONAUTE2 Enhances Grain Length and Salt Tolerance by Activating BIG GRAIN3 to Modulate Cytokinin Distribution in Rice . DOI: 10.1105/tpc.19.00542 ; PMID: 32409321
- An OsPRMT5-OsAGO2/miR1875-OsHXK1 module regulates rice immunity to blast disease . DOI: 10.1111/jipb.13430 ; PMID: 36511124
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os04g52540.1
CTCTTCTGCTTTTTAGCGAAATCCGAGAAAAAAATTGCCTGCAAAAAAAAAAATCGAAACGTCGTTCTGATCGATCGGCCGTTCGAGTTCACGGCGGAGATGGAGCACGAGCGCGGTGGCGGTGGCCGCGGCCGCGGGAGGGGTCGCGGTGGCGGGCGTGGCGGCGGTGGCGGCGATGGTCGCGGAGGCGGTTATGGTGGTGCTGGTGGTGGTGGTGTCGGCGGGCGCGGTGGGCGTGGGCCTCCTGGTGGTGGTGGTGGACGCGGGTACGAGCCCGGCGGCGGGCGTGGGTACGGTGGCGGCGGCGGCGGTGGTGGACGTGGGTATGGCGGCGGAGGCGGCGGTGGTGGGTACGAGTCCGGCGGTGGGCGTGGGTATGGCGGCGGTGGACGTGGGTATGAATCCGGCGGTGGGCGTGGACCTGGCGGCGGCGGCCGTGGGCACGAGTCCGGCGGTGGCGGTGGCCGCGGCGGGAACGTGTGGGCGCAGCCGGGGAGAGGGCGCGGAGGAGCCCCCGCCCCGGCGCCGGCGCCAGCACCAGCAGCGAGGAGGATCCAGGACGAGGGGGCCGCGAGGTCGTCGGGTACCGTTGAGCGCATTGCTTCTACTGAGGTTGTAAGAGTACAACCACCTGCACCCCCAGTTGCTGTGTCTCGTAGTGGCACGCGTGTGCCAATGCGAAGACCTGATGGTGGAGGCTCAGTATCGAAAGCCAAGGTCAAATTGTTGGTGAACCATTTTATAGTTAAGTACCGACAGGCATCAACTGTTTTTCACTATGACATAGACATCAAGCTTGATATAAGTTCCCCCAAGGCTTCAGACAAGGAGCTATCCAAGGGAGATTTTCTTACTGTCAAGGACGAGCTCTTCAAGGATGAGAGCTTTCGGCGGCTTTCATCAGCTGTTGCTTATGATGGAAAAAGAAATTTATTTACTTGTGCTGAGCTACCAGATGGTTTGTTTCGTGTCAAAGTCCGTTCACGGACTTACATTGTATCTGTGGAGTTCAAGAAGAAGCTTCCTTTGAGCCAACTCTCGGAACTGCCTGTGCCCAGAGAGGTCTTGCAGGGGCTTGATGTCATTGTGCGTGAGGCCTCTAGCTGGCGCAAGATTATCATTGGTCAGGGATTTTACTCGCAGGGCCGCAGTGTGCCCATTGGGCCGGATGTTGTAGCTCTCAAAGGAACCCAGCAGACCCTGAAATGCACTCAGAAAGGACTGATCCTTTGTGTGGACTATTCGGTTATGCCGTTTCGCAAAGCTGGACCTGTGTTGGATCTTGTTCAGAAGTCTGTGAGATACCTTGACTACAGGACAACACTAAACAAACACCAATTGGACACTTTGAAGAATGAACTCAAAGGCCAGCGTGTCACTGTAAATCATAGGAGGACAAAGCAGAAGTACATTGTTAAAGGTTTGACTGATAAACCTGCAAGTCAGATAACTTTTGTAGATTCTGAATCAGGACAGACCAAGAAGCTTCTTGATTACTATTCGCAGCAGTATGGCAAGGTTATTGAGTATCAAATGCTTCCATGCTTGGATTTGAGCAAGAGCAAGGACAAGCAAAACTATGTGCCGATTGAATTGTGTGATCTTCTTGAAGGGCAGAGATACCCAAAAGCAAGCTTAAATAGGAATTCTGATAAAACACTGAAAGAAATGGCTTTGATCCCTGCCTCAAGTAGGAAGGAGGAGATTCTGGAGTTGGTGAATGCTGACGATGGGCCTTGCAGGGGTGAAATTGCTCAGCAGTTCGGGATTTCTTTGGATGTACAAATGATGGAAGTCACTGGTAGGACCCTTCCTCCTCCCAGCCTAAAACTTGGCACCTCCAGTGGCCAACCCCCCAAATTCAATATTGATCAGCCTAACTGCCAGTGGAACCTTACGAGGAAAAGACTAGCAGAGGGCGGGGTGCTACAGTGCTGGGGCGTTGTGGACTTCAGTGCAGATTCTGGGCAGTACGCCCTGAATGGGAACATGTTTATTGACAAGATTGTCAGGAAGTGCTGCGACCTTGGCGTACAGATGAACCGTAACCCATGCATTGTGCAACTGTTAGATATGGAGGTGCTATCCGATCCACATCAGCTCTTCGAGGAGCTTAACAAAGCTAAGCAGGCGGCAGCCAGTAAGAAACAGAAGCTGCAGCTCCTCTTCTGCCCAATGTCTGATCAGCATCCTGGGTACAAGACGCTGAAGCTTATCTGCGAGACGCAGCTGGGGATCCAGACCCAGTGCTTCTTGAGCTTCCTCGCGAACAAACAACAGGGACAGGACCAGTACATGTCCAACCTTGCTCTGAAGATCAACGGCAAGATTGGAGGAAGCAACATCCAACTGTTTGGTGAATCGCTCCCGCGGATCTCCGGCGCGCCATACATGTTCATCGGCGCCGACGTGAATCACCCATCGCCGGGGAACGTCGAGAGCCCGTCGATTGCAGCAGTGGTGGCCTCGGTGGATCAAGGCGCCAGCAAGTACGTGCCAAGAATCCGCGCTCAGCCTCACCGCTGCGAGGTGATCCAGCACCTCGGCGACATGTGCAAGGAGCTCATCGGCGTGTTCGAGAAGCGGAACCGCGTGAAGCCCCAGAGGATCATCTACTTCCGCGACGGCGTCAGCGACGGTCAGTTCGACATGGTGCTGAACGAGGAGCTGGCGGACATGGAGAAGGCGATCAAGACCAAGGACTACTCCCCGACGATCACCGTGATCGTGGCCAAGAAGCGGCACCACACCAGGCTGTTCCCCAAGGACCTGAACCAGCAGCAGACCAAGAACGGCAACGTGCTCCCCGGCACGGTGGTGGACACCGGCGTGGTCGACCCGGCGGCGTACGACTTCTACCTGTGCAGCCACAACGGGCTGATCGGGACGAGCCGGCCGACGCACTACTACAGCCTTCTGGACGAGCACGGCTTCGCCTCCGACGACCTGCAGAAGCTGGTGTACAACCTCTGCTTCGTCTTCGCCCGCTGCACCAAGCCGGTGTCGCTGGCCACGCCCGTCTACTACGCCGACCTCGCCGCCTACCGCGGCAGGCTCTACTACGAGGGCATGATGATGTCGCAGCCGCCACCGTCTTCCGCGGCGTCGGCGTCGTCGGCATCCTCCTCCGGCGCCGGCGCTTCCGACTTCAGGAGCTTCCCGGCGCTGCACGAGGATCTGGTGGACAACATGTTCTTCATCTGACGACAGCCTTTCGTCGCATGGTCCGGTGGTCTCTCTCTGTTCTTAGTTTACCTCTTACTGCGTGGAGTCTCAGGTCATAGACTCATTAGTCACAGACTCACAGGTTGTCTATCTTTTGACTTTTGTTGACCGTGTCGTCGGTCTTGGTAGTTGGTAGTCTTATACATACTGTTGAGGCTGCATTATGGTTGCACAAGAAAGTTTAAGAGTACTATACTGGTACTCTGTATTTTGCAATTCTCGTGCGGATGCTATGGAGTAGGATGTTTCTAGA
CDS Sequence
- >LOC_Os04g52540.1
ATGGAGCACGAGCGCGGTGGCGGTGGCCGCGGCCGCGGGAGGGGTCGCGGTGGCGGGCGTGGCGGCGGTGGCGGCGATGGTCGCGGAGGCGGTTATGGTGGTGCTGGTGGTGGTGGTGTCGGCGGGCGCGGTGGGCGTGGGCCTCCTGGTGGTGGTGGTGGACGCGGGTACGAGCCCGGCGGCGGGCGTGGGTACGGTGGCGGCGGCGGCGGTGGTGGACGTGGGTATGGCGGCGGAGGCGGCGGTGGTGGGTACGAGTCCGGCGGTGGGCGTGGGTATGGCGGCGGTGGACGTGGGTATGAATCCGGCGGTGGGCGTGGACCTGGCGGCGGCGGCCGTGGGCACGAGTCCGGCGGTGGCGGTGGCCGCGGCGGGAACGTGTGGGCGCAGCCGGGGAGAGGGCGCGGAGGAGCCCCCGCCCCGGCGCCGGCGCCAGCACCAGCAGCGAGGAGGATCCAGGACGAGGGGGCCGCGAGGTCGTCGGGTACCGTTGAGCGCATTGCTTCTACTGAGGTTGTAAGAGTACAACCACCTGCACCCCCAGTTGCTGTGTCTCGTAGTGGCACGCGTGTGCCAATGCGAAGACCTGATGGTGGAGGCTCAGTATCGAAAGCCAAGGTCAAATTGTTGGTGAACCATTTTATAGTTAAGTACCGACAGGCATCAACTGTTTTTCACTATGACATAGACATCAAGCTTGATATAAGTTCCCCCAAGGCTTCAGACAAGGAGCTATCCAAGGGAGATTTTCTTACTGTCAAGGACGAGCTCTTCAAGGATGAGAGCTTTCGGCGGCTTTCATCAGCTGTTGCTTATGATGGAAAAAGAAATTTATTTACTTGTGCTGAGCTACCAGATGGTTTGTTTCGTGTCAAAGTCCGTTCACGGACTTACATTGTATCTGTGGAGTTCAAGAAGAAGCTTCCTTTGAGCCAACTCTCGGAACTGCCTGTGCCCAGAGAGGTCTTGCAGGGGCTTGATGTCATTGTGCGTGAGGCCTCTAGCTGGCGCAAGATTATCATTGGTCAGGGATTTTACTCGCAGGGCCGCAGTGTGCCCATTGGGCCGGATGTTGTAGCTCTCAAAGGAACCCAGCAGACCCTGAAATGCACTCAGAAAGGACTGATCCTTTGTGTGGACTATTCGGTTATGCCGTTTCGCAAAGCTGGACCTGTGTTGGATCTTGTTCAGAAGTCTGTGAGATACCTTGACTACAGGACAACACTAAACAAACACCAATTGGACACTTTGAAGAATGAACTCAAAGGCCAGCGTGTCACTGTAAATCATAGGAGGACAAAGCAGAAGTACATTGTTAAAGGTTTGACTGATAAACCTGCAAGTCAGATAACTTTTGTAGATTCTGAATCAGGACAGACCAAGAAGCTTCTTGATTACTATTCGCAGCAGTATGGCAAGGTTATTGAGTATCAAATGCTTCCATGCTTGGATTTGAGCAAGAGCAAGGACAAGCAAAACTATGTGCCGATTGAATTGTGTGATCTTCTTGAAGGGCAGAGATACCCAAAAGCAAGCTTAAATAGGAATTCTGATAAAACACTGAAAGAAATGGCTTTGATCCCTGCCTCAAGTAGGAAGGAGGAGATTCTGGAGTTGGTGAATGCTGACGATGGGCCTTGCAGGGGTGAAATTGCTCAGCAGTTCGGGATTTCTTTGGATGTACAAATGATGGAAGTCACTGGTAGGACCCTTCCTCCTCCCAGCCTAAAACTTGGCACCTCCAGTGGCCAACCCCCCAAATTCAATATTGATCAGCCTAACTGCCAGTGGAACCTTACGAGGAAAAGACTAGCAGAGGGCGGGGTGCTACAGTGCTGGGGCGTTGTGGACTTCAGTGCAGATTCTGGGCAGTACGCCCTGAATGGGAACATGTTTATTGACAAGATTGTCAGGAAGTGCTGCGACCTTGGCGTACAGATGAACCGTAACCCATGCATTGTGCAACTGTTAGATATGGAGGTGCTATCCGATCCACATCAGCTCTTCGAGGAGCTTAACAAAGCTAAGCAGGCGGCAGCCAGTAAGAAACAGAAGCTGCAGCTCCTCTTCTGCCCAATGTCTGATCAGCATCCTGGGTACAAGACGCTGAAGCTTATCTGCGAGACGCAGCTGGGGATCCAGACCCAGTGCTTCTTGAGCTTCCTCGCGAACAAACAACAGGGACAGGACCAGTACATGTCCAACCTTGCTCTGAAGATCAACGGCAAGATTGGAGGAAGCAACATCCAACTGTTTGGTGAATCGCTCCCGCGGATCTCCGGCGCGCCATACATGTTCATCGGCGCCGACGTGAATCACCCATCGCCGGGGAACGTCGAGAGCCCGTCGATTGCAGCAGTGGTGGCCTCGGTGGATCAAGGCGCCAGCAAGTACGTGCCAAGAATCCGCGCTCAGCCTCACCGCTGCGAGGTGATCCAGCACCTCGGCGACATGTGCAAGGAGCTCATCGGCGTGTTCGAGAAGCGGAACCGCGTGAAGCCCCAGAGGATCATCTACTTCCGCGACGGCGTCAGCGACGGTCAGTTCGACATGGTGCTGAACGAGGAGCTGGCGGACATGGAGAAGGCGATCAAGACCAAGGACTACTCCCCGACGATCACCGTGATCGTGGCCAAGAAGCGGCACCACACCAGGCTGTTCCCCAAGGACCTGAACCAGCAGCAGACCAAGAACGGCAACGTGCTCCCCGGCACGGTGGTGGACACCGGCGTGGTCGACCCGGCGGCGTACGACTTCTACCTGTGCAGCCACAACGGGCTGATCGGGACGAGCCGGCCGACGCACTACTACAGCCTTCTGGACGAGCACGGCTTCGCCTCCGACGACCTGCAGAAGCTGGTGTACAACCTCTGCTTCGTCTTCGCCCGCTGCACCAAGCCGGTGTCGCTGGCCACGCCCGTCTACTACGCCGACCTCGCCGCCTACCGCGGCAGGCTCTACTACGAGGGCATGATGATGTCGCAGCCGCCACCGTCTTCCGCGGCGTCGGCGTCGTCGGCATCCTCCTCCGGCGCCGGCGCTTCCGACTTCAGGAGCTTCCCGGCGCTGCACGAGGATCTGGTGGACAACATGTTCTTCATCTGA
Protein Sequence
- >LOC_Os04g52540.1
MEHERGGGGRGRGRGRGGGRGGGGGDGRGGGYGGAGGGGVGGRGGRGPPGGGGGRGYEPGGGRGYGGGGGGGGRGYGGGGGGGGYESGGGRGYGGGGRGYESGGGRGPGGGGRGHESGGGGGRGGNVWAQPGRGRGGAPAPAPAPAPAARRIQDEGAARSSGTVERIASTEVVRVQPPAPPVAVSRSGTRVPMRRPDGGGSVSKAKVKLLVNHFIVKYRQASTVFHYDIDIKLDISSPKASDKELSKGDFLTVKDELFKDESFRRLSSAVAYDGKRNLFTCAELPDGLFRVKVRSRTYIVSVEFKKKLPLSQLSELPVPREVLQGLDVIVREASSWRKIIIGQGFYSQGRSVPIGPDVVALKGTQQTLKCTQKGLILCVDYSVMPFRKAGPVLDLVQKSVRYLDYRTTLNKHQLDTLKNELKGQRVTVNHRRTKQKYIVKGLTDKPASQITFVDSESGQTKKLLDYYSQQYGKVIEYQMLPCLDLSKSKDKQNYVPIELCDLLEGQRYPKASLNRNSDKTLKEMALIPASSRKEEILELVNADDGPCRGEIAQQFGISLDVQMMEVTGRTLPPPSLKLGTSSGQPPKFNIDQPNCQWNLTRKRLAEGGVLQCWGVVDFSADSGQYALNGNMFIDKIVRKCCDLGVQMNRNPCIVQLLDMEVLSDPHQLFEELNKAKQAAASKKQKLQLLFCPMSDQHPGYKTLKLICETQLGIQTQCFLSFLANKQQGQDQYMSNLALKINGKIGGSNIQLFGESLPRISGAPYMFIGADVNHPSPGNVESPSIAAVVASVDQGASKYVPRIRAQPHRCEVIQHLGDMCKELIGVFEKRNRVKPQRIIYFRDGVSDGQFDMVLNEELADMEKAIKTKDYSPTITVIVAKKRHHTRLFPKDLNQQQTKNGNVLPGTVVDTGVVDPAAYDFYLCSHNGLIGTSRPTHYYSLLDEHGFASDDLQKLVYNLCFVFARCTKPVSLATPVYYADLAAYRGRLYYEGMMMSQPPPSSAASASSASSSGAGASDFRSFPALHEDLVDNMFFI*