Gene Details:
- MSU gene ID: LOC_Os04g51350
- RAPdb gene ID: Os04g0602600
- Gene Symbol: MPR25
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- In this study, we investigated the molecular function in rice of the mitochondrial PPR-encoding gene MITOCHONDRIAL PPR25 (MPR25), which belongs to the E subgroup of the PPR family.
- FLAG-tagged MPR25 accumulated in mitochondria but not in chloroplasts.
- Direct sequencing revealed that the MPR25 mutant fails to edit a C-U RNA editing site at nucleotide 1580 of nad5, which encodes a subunit of complex I (NADH dehydrogenase) of the respiratory chain in mitochondria.
- The MPR25 mutant may therefore provide new information on the coordinated interaction between mitochondria and chloroplasts.
- Rice MPR25 encodes a pentatricopeptide repeat protein and is essential for RNA editing of nad5 transcripts in mitochondria.
- A Tos17 knockout mutant of MPR25 exhibited growth retardation and pale-green leaves with reduced chlorophyll content during the early stages of plant development.
- We also show that splicing of chloroplast atpF transcripts is affected in the rice MPR25 mutant.
Function-related keywords:
Literature:
- Rice MPR25 encodes a pentatricopeptide repeat protein and is essential for RNA editing of nad5 transcripts in mitochondria . DOI: 10.1111/j.1365-313X.2012.05091.x ; PMID: 22747551
- AEF1/MPR25 is implicated in RNA editing of plastid atpF and mitochondrial nad5, and also promotes atpF splicing in Arabidopsis and rice . DOI: 10.1111/tpj.12756 ; PMID: 25585673
Related News:
Gene Resources:
- NCBI ID: AK120600
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os04g51350.1
ATCGAATCGTCTGTGGCGCCCGCGAAGCAACGGAAGAGATGAGGAGATGACTCGGATGAGCGGAAGCTGCAGGGAGCGAGTCGTCGTCGTCGTCGTCACCGCGAGGCGCCGCGCCAACCTCTCATGTCCTCTCCTCGCTGCGCCGTCTCGCTCCCACCCACCGCCGCGGCGACCACCGCCACCAATGGCGGAGGCGGCGGGAGGAGGAACGCGCAGCCGGCAGCGGCGACGGCGGCGTCGCAGGTGAAGAAGCTGTGCAAGCAGGGGCGGCTGGACCACGCGCGGCGGCTGCTCCTCGAGGCGCTTCCCCGGCCGCCACCGACGCTGCTCTGCAACGCGCTCCTCATCGCCTACGCCGCCCGCGCGCTCCCGGAGGAGGCGCTCCGCCTCTACGCTCTCCTCAACCACGCCGCGCGCCCGCCGGTCCGCTCCGACCACTACACCTACTCCGCCGCGCTCACCGCCTGCGCACGCTCCCGCCGCCTCCGCCTCGGGAGGTCCGTCCACGCGCACATGCTCCGGCGCGCCCGCTCCCTCCCGGACACCGCCGTCCTCCGCAACTCCCTCCTCAACCTCTACGCCTCCAGCGTGCGGTACCGGGAGGCACGCGTCGACGTCGTCCGGAGGCTGTTCGACGCAATGCCTAAGAGGAACGTGGTTTCTTGGAACACTCTGTTCGGCTGGTACGTCAAGACCGGGCGTCCCCAGGAAGCCCTGGAGCTGTTTGTGCGCATGCTAGAAGATGGTTTCAGGCCCACGCCGGTCAGCTTCGTGAATATATTTCCGGCTGCTGTGGCTGACGATCCAAGCTGGCCATTCCAGCTCTACGGATTACTTGTGAAGTATGGGGTAGAGTATATCAACGATCTGTTTGTTGTGAGCTCAGCAATCGACATGTTCTCCGAATTTGGGGATGTGCAATCAGCTCGGAGGGTGTTTGATCGTGCTGCCAAGAAGAACACCGAGGTTTGGAACACCATGATCACTGGGTATGTACAGAATGGCCAGTTTTCTGAAGCCATTGATCTCTTCAGCAAAATCTTGGGATCCCGAGAGGTTCCATTGGATGTTGTGACCTTCTTATCGGCCCTCACAGCTGCCTCACAGTCACAGGATGTTAGCTTGGGTCAGCAGCTGCATGGCTATTTGATTAAAGGAATGCATAGGACATTGCCTGTAATACTCGGTAATGCACTTGTTGTGATGTACTCAAGATGTGGCAATGTCCAAACTGCCTTTGATCTCTTCGACCGGTTGCCAGAGAAGGACATTGTTACTTGGAATACCATGGTGACTGCTTTTATACAGAACGATTTTGACTTGGAAGGCTTGCTGCTCGTCTATGAGATGCAGAAATCAGGTTTTGCTGCTGATTCTGTGACATTGACTGCAGTTCTGTCAGCATCATCAAATACTGGAGACCTTCAGATCGGTAAACAAGCACATGGTTATCTTATCAGGCATGGTATCGAGGGTGAGGGCTTGGAGAGCTACCTAATAGACATGTATGCAAAATCTGGCCGTGTAGAAATGGCTCAGAGAGTGTTTGATAGCTTTAAAAATGCCAAGAGGGATGAAGTCACTTGGAATGCCATGATAGCGGGATACACACAGAGTGGACAGCCTGAAAAGGCAATCTTAGTATTCCGGGCAATGCTTGAGGCAGGTCTTGAACCTACTTCGGTGACACTTGCTTCGGTGCTACCTGCATGTGATCCTGTTGGAGGGGGCGTTTATTCTGGGAAGCAAATCCACTGTTTTGCTGTGCGCCGTTGTTTGGATACCAATGTCTTCGTAGGTACAGCTCTTATTGACATGTACTCTAAGTGTGGTGAGATCACTACAGCAGAAAATGTCTTTGGTGGCATGACGGGGAAGAGCACTGTCACCTATACGACAATGATATCTGGTCTTGGTCAGCATGGTTTCGGCAAAAAAGCGCTTGCTCTTTTCAACTCCATGCAAGAAAAGGGGTTGAAGCCTGATGCAGTGACCTTCTTGTCTGCGATTTCAGCATGTAATTACTCTGGACTCGTCGACGAAGGACTAGCTTTGTACAGGTCGATGGACTCATTTGGAATTTCGGCTACTCCTCAGCACCACTGCTGTGTTGCAGACTTGTTAGCTAAAGCTGGAAGGGTGGAGGAAGCATACGAGTTTATAGAGGGGCTGGGGGAGGAGGGCAACTTTGTTGCCATCTGGGGATCGCTGCTTGCATCCTGCAAAGCTCAGGGCAAGCAAGAGTTGGCAAAGTTGGTGACCAAGAAGCTGCTTGACATCGAGAAGCAGTACGGTCATGCAGGCTACAGCGTTTTGTTGTCACAGGTCCTTGCTGCTGAAAGTAACTGGAATAGTGCTGATAGTCTAAGAAAGGAGATGAGGGCAAGGGGATTGAAGAAAGAAGCAGGTTCTAGTTGGATTAAAGTCCAGAACGCAGCATTGGAACACAAGTTTATCGAAAAAGACCAAAATTATGTCGAAAATGAGCACATGTTCTCGATTCTGGATGGTGATGCCGACAGTACGGATAGACTTTAACATGTTTCAATACCTTTTGGCACGCAAGATTGCAGATATGAGATTCCTAATCCTATTGTGGTGATTACCTCACGCTGACAGACTAGGCTCCTGTTTTACCTGCAGTTTAACATGATTTATCTTCATTCAGAAATCAGAATTGATGCTCCTCATAGTAATACTTGACTGGATGGAAACTTGGAAAGACACCTAGCCCACAAACCTCATGCGGCGGCCACACGGTGAACTTGTGCTGCGAGACATCAATCTATGGATGAGGTTGATACCAATGATGTGCCAGATGAAGAGCAAGCTGCAATCTTGCAGGTGGCCAGGTTGTAACTTGTATTCAGTAGTACGCATATCTTGACAAGCACAGCGCCCTCCTTAGGGATTCTGGGTGAATTGTACAGCTACATTTGCTTATAATCGTCTAGAAATAGGTGAGTACTGTCATAGAACGAGCAACGTGATTAGGCAACGGGATTTTTTTTGGTTGTGAACGTACATACAATATCTTAAATGAAGATTATTCTCACATGATTACGGCCAATGCAAAGGAGGATTTTGCATTGGTTTTCTGT
CDS Sequence
- >LOC_Os04g51350.1
ATGTCCTCTCCTCGCTGCGCCGTCTCGCTCCCACCCACCGCCGCGGCGACCACCGCCACCAATGGCGGAGGCGGCGGGAGGAGGAACGCGCAGCCGGCAGCGGCGACGGCGGCGTCGCAGGTGAAGAAGCTGTGCAAGCAGGGGCGGCTGGACCACGCGCGGCGGCTGCTCCTCGAGGCGCTTCCCCGGCCGCCACCGACGCTGCTCTGCAACGCGCTCCTCATCGCCTACGCCGCCCGCGCGCTCCCGGAGGAGGCGCTCCGCCTCTACGCTCTCCTCAACCACGCCGCGCGCCCGCCGGTCCGCTCCGACCACTACACCTACTCCGCCGCGCTCACCGCCTGCGCACGCTCCCGCCGCCTCCGCCTCGGGAGGTCCGTCCACGCGCACATGCTCCGGCGCGCCCGCTCCCTCCCGGACACCGCCGTCCTCCGCAACTCCCTCCTCAACCTCTACGCCTCCAGCGTGCGGTACCGGGAGGCACGCGTCGACGTCGTCCGGAGGCTGTTCGACGCAATGCCTAAGAGGAACGTGGTTTCTTGGAACACTCTGTTCGGCTGGTACGTCAAGACCGGGCGTCCCCAGGAAGCCCTGGAGCTGTTTGTGCGCATGCTAGAAGATGGTTTCAGGCCCACGCCGGTCAGCTTCGTGAATATATTTCCGGCTGCTGTGGCTGACGATCCAAGCTGGCCATTCCAGCTCTACGGATTACTTGTGAAGTATGGGGTAGAGTATATCAACGATCTGTTTGTTGTGAGCTCAGCAATCGACATGTTCTCCGAATTTGGGGATGTGCAATCAGCTCGGAGGGTGTTTGATCGTGCTGCCAAGAAGAACACCGAGGTTTGGAACACCATGATCACTGGGTATGTACAGAATGGCCAGTTTTCTGAAGCCATTGATCTCTTCAGCAAAATCTTGGGATCCCGAGAGGTTCCATTGGATGTTGTGACCTTCTTATCGGCCCTCACAGCTGCCTCACAGTCACAGGATGTTAGCTTGGGTCAGCAGCTGCATGGCTATTTGATTAAAGGAATGCATAGGACATTGCCTGTAATACTCGGTAATGCACTTGTTGTGATGTACTCAAGATGTGGCAATGTCCAAACTGCCTTTGATCTCTTCGACCGGTTGCCAGAGAAGGACATTGTTACTTGGAATACCATGGTGACTGCTTTTATACAGAACGATTTTGACTTGGAAGGCTTGCTGCTCGTCTATGAGATGCAGAAATCAGGTTTTGCTGCTGATTCTGTGACATTGACTGCAGTTCTGTCAGCATCATCAAATACTGGAGACCTTCAGATCGGTAAACAAGCACATGGTTATCTTATCAGGCATGGTATCGAGGGTGAGGGCTTGGAGAGCTACCTAATAGACATGTATGCAAAATCTGGCCGTGTAGAAATGGCTCAGAGAGTGTTTGATAGCTTTAAAAATGCCAAGAGGGATGAAGTCACTTGGAATGCCATGATAGCGGGATACACACAGAGTGGACAGCCTGAAAAGGCAATCTTAGTATTCCGGGCAATGCTTGAGGCAGGTCTTGAACCTACTTCGGTGACACTTGCTTCGGTGCTACCTGCATGTGATCCTGTTGGAGGGGGCGTTTATTCTGGGAAGCAAATCCACTGTTTTGCTGTGCGCCGTTGTTTGGATACCAATGTCTTCGTAGGTACAGCTCTTATTGACATGTACTCTAAGTGTGGTGAGATCACTACAGCAGAAAATGTCTTTGGTGGCATGACGGGGAAGAGCACTGTCACCTATACGACAATGATATCTGGTCTTGGTCAGCATGGTTTCGGCAAAAAAGCGCTTGCTCTTTTCAACTCCATGCAAGAAAAGGGGTTGAAGCCTGATGCAGTGACCTTCTTGTCTGCGATTTCAGCATGTAATTACTCTGGACTCGTCGACGAAGGACTAGCTTTGTACAGGTCGATGGACTCATTTGGAATTTCGGCTACTCCTCAGCACCACTGCTGTGTTGCAGACTTGTTAGCTAAAGCTGGAAGGGTGGAGGAAGCATACGAGTTTATAGAGGGGCTGGGGGAGGAGGGCAACTTTGTTGCCATCTGGGGATCGCTGCTTGCATCCTGCAAAGCTCAGGGCAAGCAAGAGTTGGCAAAGTTGGTGACCAAGAAGCTGCTTGACATCGAGAAGCAGTACGGTCATGCAGGCTACAGCGTTTTGTTGTCACAGGTCCTTGCTGCTGAAAGTAACTGGAATAGTGCTGATAGTCTAAGAAAGGAGATGAGGGCAAGGGGATTGAAGAAAGAAGCAGGTTCTAGTTGGATTAAAGTCCAGAACGCAGCATTGGAACACAAGTTTATCGAAAAAGACCAAAATTATGTCGAAAATGAGCACATGTTCTCGATTCTGGATGGTGATGCCGACAGTACGGATAGACTTTAA
Protein Sequence
- >LOC_Os04g51350.1
MSSPRCAVSLPPTAAATTATNGGGGGRRNAQPAAATAASQVKKLCKQGRLDHARRLLLEALPRPPPTLLCNALLIAYAARALPEEALRLYALLNHAARPPVRSDHYTYSAALTACARSRRLRLGRSVHAHMLRRARSLPDTAVLRNSLLNLYASSVRYREARVDVVRRLFDAMPKRNVVSWNTLFGWYVKTGRPQEALELFVRMLEDGFRPTPVSFVNIFPAAVADDPSWPFQLYGLLVKYGVEYINDLFVVSSAIDMFSEFGDVQSARRVFDRAAKKNTEVWNTMITGYVQNGQFSEAIDLFSKILGSREVPLDVVTFLSALTAASQSQDVSLGQQLHGYLIKGMHRTLPVILGNALVVMYSRCGNVQTAFDLFDRLPEKDIVTWNTMVTAFIQNDFDLEGLLLVYEMQKSGFAADSVTLTAVLSASSNTGDLQIGKQAHGYLIRHGIEGEGLESYLIDMYAKSGRVEMAQRVFDSFKNAKRDEVTWNAMIAGYTQSGQPEKAILVFRAMLEAGLEPTSVTLASVLPACDPVGGGVYSGKQIHCFAVRRCLDTNVFVGTALIDMYSKCGEITTAENVFGGMTGKSTVTYTTMISGLGQHGFGKKALALFNSMQEKGLKPDAVTFLSAISACNYSGLVDEGLALYRSMDSFGISATPQHHCCVADLLAKAGRVEEAYEFIEGLGEEGNFVAIWGSLLASCKAQGKQELAKLVTKKLLDIEKQYGHAGYSVLLSQVLAAESNWNSADSLRKEMRARGLKKEAGSSWIKVQNAALEHKFIEKDQNYVENEHMFSILDGDADSTDRL*