Gene Details:

• MSU gene ID: LOC_Os04g39020
• RAPdb gene ID: Os04g0464200
• Gene Symbol: BAD1 OsBADH1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Northern blot analysis revealed that salt-tolerant in each rice cultivar is correlated to the expression level of OsBADH1 mRNA.
• Moreover, these results suggest that the expression of OsBADH1 gene in response to salt stress could be magnified under high light conditions.
• Interestingly, the effect of salt stress on the expression of OsBADH1 gene was alleviated by CO2 enrichment.
• Expression of OsBADH1 gene in Indica rice (Oryza sativaL.) in correlation with salt, plasmolysis, temperature and light stresses.
• We previously found that the expression of betaine aldehyde dehydrogenase 1 gene (OsBADH1), encoding a key enzyme for glycine betaine biosynthesis pathway, showed close correlation with salt tolerance of rice.
• In this study, the expression of the OsBADH1 gene in transgenic tobacco was investigated in response to salt stress using a transgenic approach.
• The expression studies showed that OsBADH1 can be induced by a variety of environmental factors such as salinity, drought, cold, heat, light intensity and CO2 concentration.
• The results demonstrated that the OsBADH1 mRNA expression was up-regulated by salinity, drought, cold and high light intensity but down-regulated by CO2 enrichment and heat stress.
• The primary response of OsBADH1 gene expression was induced within 24 h after salinity, cold or drought stress treatment.
• Expression of Indica rice OsBADH1 gene under salinity stress in transgenic tobacco.
• Japonica rice (salt-sensitive) was genetically engineered to enhance salt tolerance by introducing the OsBADH1 gene from Indica rice (salt-tolerant), which is a GB accumulator.
• Genetic manipulation of Japonica rice using the OsBADH1 gene from Indica rice to improve salinity tolerance.
• The accumulation of OsBADH1 mRNA decreases following submergence treatment, but quickly recovers after re-aeration.
• Transgenic rice lines downregulating OsBADH1 exhibited remarkably reduced tolerance to NaCl, drought and cold stresses.
• In this study, we demonstrated a pivotal role of OsBADH1 in stress tolerance without altering GB biosynthesis capacity, using the RNA interference (RNAi) technique.

Function-related keywords:

• salt ,  drought ,  salinity ,  temperature ,  salt-stress ,  salt-tolerance ,  salinity-stress ,  submergence ,  tolerance ,  stress

Literature:

• OsBADH1 is possibly involved in acetaldehyde oxidation in rice plant peroxisomes .  DOI:  10.1016/j.febslet.2009.10.039 ;  PMID:  19850038
• Dissecting substrate specificity of two rice BADH isoforms: Enzyme kinetics, docking and molecular dynamics simulation studies .  DOI:  10.1016/j.biochi.2012.04.009 ;  PMID:  22534193
• Genomic insight into genetic changes and shaping of major inbred rice cultivars in China .  DOI:  10.1111/nph.18500 ;  PMID:  36114658
• Expression of OsBADH1 gene in Indica rice (Oryza sativa L.) in correlation with salt, plasmolysis, temperature and light stresses .  DOI:  10.1007/s11816-009-0123-6
• Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice .  DOI:  10.1007/s11103-008-9381-x ;  PMID:  18704694
• Expression of Indica rice OsBADH1 gene under salinity stress in transgenic tobacco .  DOI:  10.1007/s11816-009-0123-6
• RNAi-directed downregulation of betaine aldehyde dehydrogenase 1 (OsBADH1) results in decreased stress tolerance and increased oxidative markers without affecting glycine betaine biosynthesis in rice (Oryza sativa) .  DOI:  10.1007/s11103-014-0239-0 ;  PMID:  25150410
• Resequencing Reveals Different Domestication Rate for BADH1 and BADH2 in Rice (Oryza sativa) .  DOI:  10.1371/journal.pone.0134801 ;  PMID:  26258482

Related News:

Gene Resources:

• NCBI ID: BAA21098
• UniProt accessions:

Sequences: