Gene Details:
- MSU gene ID: LOC_Os04g37960
- RAPdb gene ID: Os04g0452500
- Gene Symbol: ZEP1 OsZEP
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- In the absence of OsAM1, many other critical meiotic components, including PAIR2, ZEP1 and OsMER3, could not be correctly installed onto chromosomes.
- The expression levels of the drought-responsive genes RD22, SODA1, bZIP46 and POD, as well as the ABA synthetic gene ZEP1 were up-regulated in the OsDIL-overexpression lines but the ABA degradation gene ABAOX3 was down-regulated.
- In addition, ZEP1 is reloaded onto chromosomes in early microspores as the chromosome decondense, suggesting that ZEP1 might have other biological functions during this process.
- The central element protein ZEP1 of the synaptonemal complex regulates the number of crossovers during meiosis in rice.
- Finally, we found that the centromeric localization of OsSGO1 depends on OsAM1, not other meiotic proteins such as OsREC8, PAIR2, OsMER3, or ZEP1.
- Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal.
- Moreover, OsCOM1 was loaded normally onto meiotic chromosomes in Osrec8, ZEP1 and Osmer3 mutants, but could not be properly loaded in Osam1, pair2 and OsSPO11-1(RNAi) plants.
- In contrast, in pair2, Osmer3 and ZEP1 mutants, OsAM1 could be loaded normally, suggesting that OsAM1 plays a fundamental role in building the proper chromosome structure at the beginning of meiosis.
- Carotenoids enter the xanthophyll cycle, and the metabolites that differentially accumulate in the striped leaves include zeaxanthin and its derivatives for photooxidative stress protection, driven by the upregulated expression of OsZEP.
Function-related keywords:
- meiotic , drought , microspore , meiosis , ABA , stress , oxidative-stress
Literature:
- OsAM1 is required for leptotene-zygotene transition in rice . DOI: 10.1038/cr.2011.7 ; PMID: 21221128
- ZIP4 in homologous chromosome synapsis and crossover formation in rice meiosis . DOI: 10.1242/jcs.090993 ; PMID: 22393242
- OsSGO1 maintains synaptonemal complex stabilization in addition to protecting centromeric cohesion during rice meiosis . DOI: 10.1111/j.1365-313X.2011.04615.x ; PMID: 21615569
- The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis . DOI: 10.1111/j.1365-313X.2012.05025.x ; PMID: 22507309
- The central element protein ZEP1 of the synaptonemal complex regulates the number of crossovers during meiosis in rice . DOI: 10.1105/tpc.109.070789 ; PMID: 20154151
- Central region component1, a novel synaptonemal complex component, is essential for meiotic recombination initiation in rice . DOI: 10.1105/tpc.113.113175 ; PMID: 23943860
- OsREC8 is essential for chromatid cohesion and metaphase I monopolar orientation in rice meiosis . DOI: 10.1104/pp.111.177428 ; PMID: 21606318
- OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice . DOI: 10.1007/s00412-010-0284-7 ; PMID: 20625906
- The rice OsDIL gene plays a role in drought tolerance at vegetative and reproductive stages . DOI: 10.1007/s11103-013-0057-9 ; PMID: 23686450
- Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells . DOI: 10.3389/fpls.2020.600820 ; PMID: 33304374
- Cia Zeaxanthin Biosynthesis, OsZEP and OsVDE Regulate Striped Leaves Occurring in Response to Deep Transplanting of Rice . DOI: 10.3390/ijms23158340 ; PMID: 35955477
Related News:
Gene Resources:
- NCBI ID: GU479042
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os04g37960.1
ATGCAGAAGCTGGGTTTATCGGGGCTTAGGGGTCTCGAGGGGTTCCGATCTCTCGCTGGATCCACCTCGACGGCCGCGAAGGCCCCGAACCCCAAGCCGTCGTCCGATATTGGAGGGAGCACGTACGGGAGCTTCGCCAATCTTAAGATCACAGCAGAAAAGCTGGTTAAGGAGCAGGCTTCAGTGAAGACTGATCTAGAAATGACGGTATATTTTTCAGCGTTTACCATTATTTATGGAAATTTTACTGGATGGGTATATGGCAATATTATCTTTACTGTAGTCATCTTTCATGGTGCAAATGTTCTAGTTATATCATGGATAAAAGAAGCAAAGCTCCAACAAGCTGTCAATGAAAATGCAAAGCTTAAGGTGAAACAGACTGAAGATTCAAAGCTCTGGCAGGGATTAGATTCAAAAGTTTCCTCAACAAAGACTTTGTGCAATCAACTGACAGAAACTCTGCAGCAGTTAGCTAGTCAGACAGAAAGAGCTGAGGAAGATAAGAAGTTTTTTGAGGAGATTCTTGGCAAGAATTCAAAAGCTTTTGAAGAATTCAACTGCCTGTTGCACGATTCATCAATAAAACTGGAATGTGCAGAACAAATGATCATTTCAGGGAAACAGGAGATGTTGCGGATCAAACAAGAGAAAGAAGAGATGGATCAGAGTTACAAGGAACAGCTATATGCAAGTGATACTACCATAAGAGAAAAAAATTCTCTCATCAAACAGTTGGAAGATTCCATTGAACAAAATAAAGCCCGACTGTTGTATGTTGACTCCCGTTTGGAATGCATGGAGCAAGAGTTGAAGCTAAAAGAAGATGTTTGCATTTGTCTGAAAGAAAACCTGGCAAGCACTGAAAGTGAAAAGAATGACTTGAAGCTTAGGAACGAGGGCTACACTTTGGAAGTTCAGAAACTATCCAAGGACAACAAGGAGCTTAATGAATTGCTTAGTGGTTTTACGGTTAAGGTAACTGAGCTAGATAAAGAGCACACATCAATTTCAAGTCATGTCACTCAGTTGATTTCTTCATTTGAGAGATATGATGGAAAGGTTCACGAGGAAAAAATGTTGATGATAAAATCTGCCAAGGACAAATTTGAACATCTCCAAAATCAGTATGTAAATTTGATATCAGAAAACAATGCTCTCCAAACTGAAATCGAGGAGCTGAAGTCCAGAATCATAGAGCTGCAGAAAACTCAAGAGATTGTCATGGTTCAACATGTAGAAGAATGCCAAGTTGCTGAAGATAAGATCAGAAGATTGGAGTCTGAAGCAGAAATTTCTGCCTCCAACATTAGTCAGCTAGAAAAGGTAGCTTCTGACCTAGAAGGGAGGGTTCAAAAACTTCTGGAGGATTCTAGATCTGCTGAAAATCACAAGCAAGAGTTGCTTCAGAAGATTCTGAAGCTAGAATCAGATAATCAGGAGCTTCTAGGTCGAGTGCAATCTGTTTTGAATGAGAAGTCTAATGATACGGAATCTCTGCAAGGAGAGATAGCTAAGCGTGACCAACAGGTTGAGACACTTGAGAACCAGGTCAATCAGCTTTGCAGTATTATTGATGAGAAAGAACAACTACACACTTGTGCTGTAGAAAGAGAGAAGAATTTAGAGGAACAGAAGTTACAGGTCCAAGCATCACTTGCTGCAACAGAAAGCCAACTTACTGAGGCAAAAAAACAGTATGATATCATGCTTGAAGGTAAAAAGATAGAGCTGTCCAAGCATCTGAAAGAATTATCACTGAAAAATGACCAGGCAATCAATGAAATCCGTAGGAAATATGAACTAGAAAAGGTAGAAATCATTAATATTGAAAAAGAAAAGGCCGAGAAGCTCATAAAGGAAATGGAAAACAAATGCAATGAAAAGATTTCAGAAAACAGGCAAGATTCTGAGAGCAGTTTTGAGATGGTTGCAAGAATTCAGCAGGATAATGAGCATAAGGAATCAACTCTTCGAGCTTATCATAAAGAAGAACTCCAGCGCATCCAATCTCAGGCTGAGAATGAATTGAGGGAGAGATTGTCATCGCTCAGAAAGGATCATGAAATTCAAATGAAATCATTGACTAAAAAGCATGAGGAAAATTGTCAGAAGCTTCAGGATGAACTGGAGCTTCAGAAGTCAAAGGAGGAGAAGCAAAGAGCATTGTTACAGTTACAATGGAAAGTAATGGGCGAAACCCAACAGGTTGATCAAGAAGTAAACTCTAAGAAGGAATACTCTGTTTCATCAATAAAGAGGAGAGATCCATATATCAGAAAAGAACATCAGCTTCAGTTGGTTAGTCCTGAGACCAAACGGAAGGATGTTAATCTATCTGGCATTATACAATCACCAATTACAAACATGCTGAGAAAGGTAGAGAAAGGAACCCAGGATATTCCTAAGCATAGAAAGGTAACACATCATGAATATGAAGTTGAGACAGCAAATGGAAGAATCACAAAGCGCAGGAAAACTAAGAGCACCGTCATGTTTGGGGAACCCAACACTCAGAAGTCATTGCATGATACTGCTGACAAGGATCCTACAAAAATGAAGAAGGTTGTTGCTGGATCCCATCCCCACCCTGCAAACATTGGTGAATTGTTTTCTGAGGGCTCGTTGAATCCATATGCCGAAGATCCTTATGCATTTGGCTAGAAGCTCACATTTGAGGTGCTGACCTTCAGAAGCATGATGATGACTCCCGAGTGCAATCCCCAAGTCGGATTGAATCAATGATCTTGCGGCCTTAGGCATCTGACCATCCTGTTGTACGAAACGACAATCGTTAACTGCGTTGTATCTGCAATACTGTTACGACACGGGTTATGGCATCTGACCATCCTGGTGTTCATAACATACTATCACTACCTGTGATGTATCTGGAATATCGATACGACAGACAACGATTCTCCTGCGCGTACAGCATCAACTGAAAA
CDS Sequence
- >LOC_Os04g37960.1
ATGCAGAAGCTGGGTTTATCGGGGCTTAGGGGTCTCGAGGGGTTCCGATCTCTCGCTGGATCCACCTCGACGGCCGCGAAGGCCCCGAACCCCAAGCCGTCGTCCGATATTGGAGGGAGCACGTACGGGAGCTTCGCCAATCTTAAGATCACAGCAGAAAAGCTGGTTAAGGAGCAGGCTTCAGTGAAGACTGATCTAGAAATGACGGTATATTTTTCAGCGTTTACCATTATTTATGGAAATTTTACTGGATGGGTATATGGCAATATTATCTTTACTGTAGTCATCTTTCATGGTGCAAATGTTCTAGTTATATCATGGATAAAAGAAGCAAAGCTCCAACAAGCTGTCAATGAAAATGCAAAGCTTAAGGTGAAACAGACTGAAGATTCAAAGCTCTGGCAGGGATTAGATTCAAAAGTTTCCTCAACAAAGACTTTGTGCAATCAACTGACAGAAACTCTGCAGCAGTTAGCTAGTCAGACAGAAAGAGCTGAGGAAGATAAGAAGTTTTTTGAGGAGATTCTTGGCAAGAATTCAAAAGCTTTTGAAGAATTCAACTGCCTGTTGCACGATTCATCAATAAAACTGGAATGTGCAGAACAAATGATCATTTCAGGGAAACAGGAGATGTTGCGGATCAAACAAGAGAAAGAAGAGATGGATCAGAGTTACAAGGAACAGCTATATGCAAGTGATACTACCATAAGAGAAAAAAATTCTCTCATCAAACAGTTGGAAGATTCCATTGAACAAAATAAAGCCCGACTGTTGTATGTTGACTCCCGTTTGGAATGCATGGAGCAAGAGTTGAAGCTAAAAGAAGATGTTTGCATTTGTCTGAAAGAAAACCTGGCAAGCACTGAAAGTGAAAAGAATGACTTGAAGCTTAGGAACGAGGGCTACACTTTGGAAGTTCAGAAACTATCCAAGGACAACAAGGAGCTTAATGAATTGCTTAGTGGTTTTACGGTTAAGGTAACTGAGCTAGATAAAGAGCACACATCAATTTCAAGTCATGTCACTCAGTTGATTTCTTCATTTGAGAGATATGATGGAAAGGTTCACGAGGAAAAAATGTTGATGATAAAATCTGCCAAGGACAAATTTGAACATCTCCAAAATCAGTATGTAAATTTGATATCAGAAAACAATGCTCTCCAAACTGAAATCGAGGAGCTGAAGTCCAGAATCATAGAGCTGCAGAAAACTCAAGAGATTGTCATGGTTCAACATGTAGAAGAATGCCAAGTTGCTGAAGATAAGATCAGAAGATTGGAGTCTGAAGCAGAAATTTCTGCCTCCAACATTAGTCAGCTAGAAAAGGTAGCTTCTGACCTAGAAGGGAGGGTTCAAAAACTTCTGGAGGATTCTAGATCTGCTGAAAATCACAAGCAAGAGTTGCTTCAGAAGATTCTGAAGCTAGAATCAGATAATCAGGAGCTTCTAGGTCGAGTGCAATCTGTTTTGAATGAGAAGTCTAATGATACGGAATCTCTGCAAGGAGAGATAGCTAAGCGTGACCAACAGGTTGAGACACTTGAGAACCAGGTCAATCAGCTTTGCAGTATTATTGATGAGAAAGAACAACTACACACTTGTGCTGTAGAAAGAGAGAAGAATTTAGAGGAACAGAAGTTACAGGTCCAAGCATCACTTGCTGCAACAGAAAGCCAACTTACTGAGGCAAAAAAACAGTATGATATCATGCTTGAAGGTAAAAAGATAGAGCTGTCCAAGCATCTGAAAGAATTATCACTGAAAAATGACCAGGCAATCAATGAAATCCGTAGGAAATATGAACTAGAAAAGGTAGAAATCATTAATATTGAAAAAGAAAAGGCCGAGAAGCTCATAAAGGAAATGGAAAACAAATGCAATGAAAAGATTTCAGAAAACAGGCAAGATTCTGAGAGCAGTTTTGAGATGGTTGCAAGAATTCAGCAGGATAATGAGCATAAGGAATCAACTCTTCGAGCTTATCATAAAGAAGAACTCCAGCGCATCCAATCTCAGGCTGAGAATGAATTGAGGGAGAGATTGTCATCGCTCAGAAAGGATCATGAAATTCAAATGAAATCATTGACTAAAAAGCATGAGGAAAATTGTCAGAAGCTTCAGGATGAACTGGAGCTTCAGAAGTCAAAGGAGGAGAAGCAAAGAGCATTGTTACAGTTACAATGGAAAGTAATGGGCGAAACCCAACAGGTTGATCAAGAAGTAAACTCTAAGAAGGAATACTCTGTTTCATCAATAAAGAGGAGAGATCCATATATCAGAAAAGAACATCAGCTTCAGTTGGTTAGTCCTGAGACCAAACGGAAGGATGTTAATCTATCTGGCATTATACAATCACCAATTACAAACATGCTGAGAAAGGTAGAGAAAGGAACCCAGGATATTCCTAAGCATAGAAAGGTAACACATCATGAATATGAAGTTGAGACAGCAAATGGAAGAATCACAAAGCGCAGGAAAACTAAGAGCACCGTCATGTTTGGGGAACCCAACACTCAGAAGTCATTGCATGATACTGCTGACAAGGATCCTACAAAAATGAAGAAGGTTGTTGCTGGATCCCATCCCCACCCTGCAAACATTGGTGAATTGTTTTCTGAGGGCTCGTTGAATCCATATGCCGAAGATCCTTATGCATTTGGCTAG
Protein Sequence
- >LOC_Os04g37960.1
MQKLGLSGLRGLEGFRSLAGSTSTAAKAPNPKPSSDIGGSTYGSFANLKITAEKLVKEQASVKTDLEMTVYFSAFTIIYGNFTGWVYGNIIFTVVIFHGANVLVISWIKEAKLQQAVNENAKLKVKQTEDSKLWQGLDSKVSSTKTLCNQLTETLQQLASQTERAEEDKKFFEEILGKNSKAFEEFNCLLHDSSIKLECAEQMIISGKQEMLRIKQEKEEMDQSYKEQLYASDTTIREKNSLIKQLEDSIEQNKARLLYVDSRLECMEQELKLKEDVCICLKENLASTESEKNDLKLRNEGYTLEVQKLSKDNKELNELLSGFTVKVTELDKEHTSISSHVTQLISSFERYDGKVHEEKMLMIKSAKDKFEHLQNQYVNLISENNALQTEIEELKSRIIELQKTQEIVMVQHVEECQVAEDKIRRLESEAEISASNISQLEKVASDLEGRVQKLLEDSRSAENHKQELLQKILKLESDNQELLGRVQSVLNEKSNDTESLQGEIAKRDQQVETLENQVNQLCSIIDEKEQLHTCAVEREKNLEEQKLQVQASLAATESQLTEAKKQYDIMLEGKKIELSKHLKELSLKNDQAINEIRRKYELEKVEIINIEKEKAEKLIKEMENKCNEKISENRQDSESSFEMVARIQQDNEHKESTLRAYHKEELQRIQSQAENELRERLSSLRKDHEIQMKSLTKKHEENCQKLQDELELQKSKEEKQRALLQLQWKVMGETQQVDQEVNSKKEYSVSSIKRRDPYIRKEHQLQLVSPETKRKDVNLSGIIQSPITNMLRKVEKGTQDIPKHRKVTHHEYEVETANGRITKRRKTKSTVMFGEPNTQKSLHDTADKDPTKMKKVVAGSHPHPANIGELFSEGSLNPYAEDPYAFG*