Gene Details:

• MSU gene ID: LOC_Os04g37500
• RAPdb gene ID: Os04g0447800
• Gene Symbol: OsGAD2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• RNA analysis showed that transcripts of OsGAD1 and OsGAD2 were present in all tissues examined, but their expression was differentially regulated, at least in roots and maturing seeds.
• We have isolated full-length cDNAs for two distinct isoforms of glutamate decarboxylase (GAD), designated OsGAD1 and OsGAD2 from a rice shoot cDNA library.
• Regenerated OsGAD2DeltaC rice plants had aberrant phenotypes such as dwarfism, etiolated leaves, and sterility.
• Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats.

Function-related keywords:

• root ,  shoot ,  dwarf ,  grain ,  seed ,  sterility

Literature:

• Rice (Oryza sativa) contains a novel isoform of glutamate decarboxylase that lacks an authentic calmodulin-binding domain at the C-terminus .  DOI:  10.1016/s0167-4781(01)00324-4 ;  PMID:  11779628
• Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats .  DOI:  10.1007/s11248-009-9272-1 ;  PMID:  19434509
• C-terminal extension of rice glutamate decarboxylase (OsGAD2) functions as an autoinhibitory domain and overexpression of a truncated mutant results in the accumulation of extremely high levels of GABA in plant cells .  DOI:  10.1093/jxb/erm120 ;  PMID:  17562689

Related News:

Gene Resources:

• NCBI ID: AB056061
• UniProt accessions:

Sequences: