Gene Details:

Functional Descriptions:

  • The nearly-isogenic line (NIL-An-1) carrying a wild allele An-1 in the genetic background of the awnless indica Guangluai4 produces long awns and longer grains, but significantly fewer grains per panicle compared with Guangluai4.
  • Thus, we propose that awn loss was favored and strongly selected by humans, as genetic variations at the An-1 locus that cause awn loss would increase grain numbers and subsequently improve grain yield in cultivated rice.
  • Transgenic studies confirmed that An-1 positively regulates awn elongation, but negatively regulates grain number per panicle.
  • An-1 encodes a basic helix-loop-helix protein that regulates awn development, grain size, and grain number in rice.
  • We report here the molecular cloning of a major quantitative trait locus, An-1, which regulates long awn formation in O.
  • Genetic variations in the An-1 locus were found to be associated with awn loss in cultivated rice.
  • An-1 encodes a basic helix-loop-helix protein, which regulates cell division.
  • Analyses of minimum spanning trees and introgression regions demonstrated that An-1, an important gene for awn formation, was preferentially domesticated, and its mutation to An-1 was followed by GLA and An-2.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >LOC_Os04g28280.1
    ATGAACCCCACCACCGCCGCCGCCGCCGACCAACCATCCAAGCCCTCCGCCGCCGCCGCCGCCCGGAAGCGCAAGTCGTCGGCGAAGCCCAAGGCCTCGTCCTCATCCTTACCCACGGCCACGGCGACGACGAACGCGAGCCCGAAGCGGTCCAAGGTCGCCGCCGGCGCCGGAGACGACGGCGACGCCGACGCCGACGCGGCGGAGGAGAAGCCGGAGCCAGCCAAAGACTACATCCATGTGAGGGCGAGGCGGGGGCAAGCCACCGATAGCCATAGCCTCGCCGAGAGGGTGAGGAGGGAGAGGATAAGCGAGAGGATGAAGCTTCTGCAGTCGCTCGTGCCAGGCTGCAACAAGATCACCGGCAAGGCTCTCATGCTGGACGAGATCATCAACTATGTGCAGTCGCTGCAGCGTCAGGTCGAGTTTTTGTCCATGAAGTTGGCGACCATGAATCCTCAGCTGGACTTTGACAGCCATTACATGCCTTCCAAAGATATGAGCCATATGCCAGTACCCGCATACCCGTCAAGCGATCCGACCACCACCACCGCGTTCTCCTACACCGGCTCACCCGCCACTGCTGATCCATTCACCGTCTACAACTGCTGGGAGCTCGACCTCCACACCGCTATGCAAATGGGAGCCACCACCGGACTCAGCCAAGACGGTCCAATCGCAACGATGGCACCCTCTCCCTCGCCATTGCCGCACCATCCTCCTCTTCACGGCTTCTACGGGGGGCAGCAGCAGCAGGGGACGACAGTAAACCACATGAAGGCCGAGCCATAA
CDS Sequence
  • >LOC_Os04g28280.1
    ATGAACCCCACCACCGCCGCCGCCGCCGACCAACCATCCAAGCCCTCCGCCGCCGCCGCCGCCCGGAAGCGCAAGTCGTCGGCGAAGCCCAAGGCCTCGTCCTCATCCTTACCCACGGCCACGGCGACGACGAACGCGAGCCCGAAGCGGTCCAAGGTCGCCGCCGGCGCCGGAGACGACGGCGACGCCGACGCCGACGCGGCGGAGGAGAAGCCGGAGCCAGCCAAAGACTACATCCATGTGAGGGCGAGGCGGGGGCAAGCCACCGATAGCCATAGCCTCGCCGAGAGGGTGAGGAGGGAGAGGATAAGCGAGAGGATGAAGCTTCTGCAGTCGCTCGTGCCAGGCTGCAACAAGATCACCGGCAAGGCTCTCATGCTGGACGAGATCATCAACTATGTGCAGTCGCTGCAGCGTCAGGTCGAGTTTTTGTCCATGAAGTTGGCGACCATGAATCCTCAGCTGGACTTTGACAGCCATTACATGCCTTCCAAAGATATGAGCCATATGCCAGTACCCGCATACCCGTCAAGCGATCCGACCACCACCACCGCGTTCTCCTACACCGGCTCACCCGCCACTGCTGATCCATTCACCGTCTACAACTGCTGGGAGCTCGACCTCCACACCGCTATGCAAATGGGAGCCACCACCGGACTCAGCCAAGACGGTCCAATCGCAACGATGGCACCCTCTCCCTCGCCATTGCCGCACCATCCTCCTCTTCACGGCTTCTACGGGGGGCAGCAGCAGCAGGGGACGACAGTAAACCACATGAAGGCCGAGCCATAA
Protein Sequence
  • >LOC_Os04g28280.1
    MNPTTAAAADQPSKPSAAAAARKRKSSAKPKASSSSLPTATATTNASPKRSKVAAGAGDDGDADADAAEEKPEPAKDYIHVRARRGQATDSHSLAERVRRERISERMKLLQSLVPGCNKITGKALMLDEIINYVQSLQRQVEFLSMKLATMNPQLDFDSHYMPSKDMSHMPVPAYPSSDPTTTTAFSYTGSPATADPFTVYNCWELDLHTAMQMGATTGLSQDGPIATMAPSPSPLPHHPPLHGFYGGQQQQGTTVNHMKAEP*