Gene Details:

• MSU gene ID: LOC_Os04g24530
• RAPdb gene ID: Os04g0310800
• Gene Symbol: OsACOS12
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• ACOS5 and OsACOS12 are conserved for pollen wall formation in monocot and dicot species.
• The localization of OsACOS12-GFP demonstrated that OsACOS12 protein is accumulated in tapetal cells and anther locules.
• The OsACOS12 mutation caused by a pre-mature stop codon in LOC_Os04g24530 exhibits defective sexine resulting in a male sterile phenotype in rice.
• OsACOS12 driven by the ACOS5 promoter could partially restore the male fertility of the acos5 mutant in Arabidopsis.
• In situ hybridization shows that OsACOS12 is expressed in tapetal cells and microspores at the transcript level.
• Loss of function mutation of rice OsACOS12 impairs lipid metabolism-mediated anther cuticle and pollen wall formation, and interferes with tapetum programmed cell death, leading to male sterility.
• Rice fatty acyl-CoA synthetase OsACOS12 is required for tapetum programmed cell death and male fertility.
• Those phenotypic changes were evident at stage 10, during which OsACOS12 had its maximum expression in tapetal cells and microspores.
• A complementation test showed that OsACOS12 driven by the ACOS5 promoter could partially restore the male fertility of the acos5 mutant in Arabidopsis, while PpACOS6 did not rescue the acos5 phenotype.

Function-related keywords:

• pollen ,  anther ,  sterile ,  fertility ,  tapetal ,  pollen-wall ,  sterility ,  cell-death ,  cuticle ,  tapetum ,  male-sterility

Literature:

• OsACOS12, an orthologue of Arabidopsis acyl-CoA synthetase5, plays an important role in pollen exine formation and anther development in rice .  DOI:  10.1186/s12870-016-0943-9 ;  PMID:  27871243
• Rice fatty acyl-CoA synthetase OsACOS12 is required for tapetum programmed cell death and male fertility .  DOI:  10.1007/s00425-017-2691-y ;  PMID:  28382520
• Acyl-CoA synthetases from Physcomitrella, rice and Arabidopsis: different substrate preferences but common regulation by MS188 in sporopollenin synthesis .  DOI:  10.1007/s00425-019-03189-0 ;  PMID:  31111205
• OsMS188 Is a Key Regulator of Tapetum Development and Sporopollenin Synthesis in Rice .  DOI:  10.1186/s12284-020-00451-y ;  PMID:  33409767

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: