Gene Details:

• MSU gene ID: LOC_Os04g17660
• RAPdb gene ID: Os04g0249600
• Gene Symbol: OsHAC1 2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• OsHAC1:1 and OsHAC1;2 are predominantly expressed in roots, with OsHAC1;1 being abundant in the epidermis, root hairs and pericycle cells while OsHAC1;2 is abundant in the epidermis, outer layers of cortex and endodermis cells.
• When grown under aerobic soil conditions overexpression of either OsHAC1;1 or OsHAC1;2 also decreased As accumulation in rice grain, whereas grain As increased in the knockout mutants.
• We conclude that OsHAC1;1 and OsHAC1;2 are arsenate reductases that play an important role in restricting As accumulation in rice shoots and grain.
• In contrast, overexpression of either OsHAC1;1 or OsHAC1;2 increased arsenite efflux, reduced As accumulation and enhanced arsenate tolerance.
• OsHAC1;1 and OsHAC1;2 are able to complement an Escherichia coli mutant lacking the endogenous arsenate reductase and to reduce arsenate to arsenite.
• Knocking out OsHAC1;1 or OsHAC1;2 decreased the reduction of arsenate to arsenite in roots, reducing arsenite efflux to the external medium.
• OsHAC1;1 and OsHAC1;2 Function as Arsenate Reductases and Regulate Arsenic Accumulation.

Function-related keywords:

• root ,  grain ,  tolerance ,  arsenite ,  root-hair ,  arsenic-accumulation

Literature:

• OsHAC1;1 and OsHAC1;2 Function as Arsenate Reductases and Regulate Arsenic Accumulation .  DOI:  10.1104/pp.16.01332 ;  PMID:  27702843

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: