Gene Details:

• MSU gene ID: LOC_Os03g61829
• RAPdb gene ID: Os03g0834050
• Gene Symbol: OsHAD1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Exogenous application of recombinant OsHAD1 protein in growth media supplemented with phytate, led to marked increase in growth and total P content of Pi deficient WT rice seedlings.
• Further, overexpression of OsHAD1 in rice resulted in enhanced phosphatase activity, biomass, total and soluble P content in Pi deficient transgenic seedlings treated with phytate as restricted Pi source.
• We conclude that besides dephosphorylation of cellular organic-P, OsHAD1 in coordination with kinases may regulate phosphorylation status of downstream targets to accomplish Pi homeostasis under limited Pi supply.
• Here, we identified and characterized a PHR2 regulated; novel low Pi responsive haloacid dehalogenase (HAD)-like hydrolase, OsHAD1.
• While, OsHAD1 is a functional HAD protein having both acid phosphatase and phytase activity; it showed little homology with other known low Pi responsive HAD superfamily members.
• To elucidate the underlying regulatory mechanisms of OsHAD1, we performed in-vitro pull down assays which revealed association of OsHAD1 with protein kinases.

Function-related keywords:

• seedlings ,  growth ,  homeostasis ,  Pi ,  pi ,  Pi-homeostasis ,  protein-kinase

Literature:

• OsHAD1, a Haloacid Dehalogenase-Like APase, Enhances Phosphate Accumulation .  DOI:  10.1104/pp.17.00571 ;  PMID:  28637831

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: