Gene Details:
- MSU gene ID: LOC_Os03g54091
- RAPdb gene ID: Os03g0752200
- Gene Symbol: OsSPO11-1 OsTOP6A1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Rice plants with loss-of-function of OsSPO11-1 have no apparent growth defects during vegetative development, but homologous chromosome pairing and recombination are significantly obstructed.
- Moreover, OsCOM1 was loaded normally onto meiotic chromosomes in Osrec8, zep1 and Osmer3 mutants, but could not be properly loaded in Osam1, pair2 and OsSPO11-1(RNAi) plants.
- The over expression of OsTOP6A1 in transgenic Arabidopsis plants driven by cauliflower mosaic virus-35S promoter resulted in pleiotropic effects on plant growth and development.
- OsTOP6A1 was predominantly expressed in prepollinated flowers.
- Although AtSPO11-1, the homolog of OsTOP6A1 in Arabidopsis, has been implicated in meiotic recombination; the present study demonstrates possible additional role of OsTOP6A1 and provides an effective tool for engineering crop plants for tolerance to different environmental stresses.
- Constitutive expression of a meiotic recombination protein gene homolog, OsTOP6A1, from rice confers abiotic stress tolerance in transgenic Arabidopsis plants.
- Thus, OsSPO11-1 is essential for both homologous chromosomes pairing and crossover formation during meiosis in rice.
Function-related keywords:
- growth , vegetative , meiotic , flower , meiosis , abiotic-stress
Literature:
- The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis . DOI: 10.1111/j.1365-313X.2012.05025.x ; PMID: 22507309
- Overexpression of putative topoisomerase 6 genes from rice confers stress tolerance in transgenic Arabidopsis plants . DOI: 10.1111/j.1742-4658.2006.05518.x ; PMID: 17116242
- Constitutive expression of a meiotic recombination protein gene homolog, OsTOP6A1, from rice confers abiotic stress tolerance in transgenic Arabidopsis plants . DOI: 10.1007/s00299-007-0491-8 ; PMID: 18071708
- OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice . DOI: 10.1007/s00412-010-0284-7 ; PMID: 20625906
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os03g54091.1
AGCCGTTGTTGGCCCGACCGCCGGAGGCTCACTCGCAGCGGTCGATCATGGCGGGGAGGGAGAAGAGGCGGCGGGTGGCGGCGCTCGACGGCGAAGAGCGGCGGCGGCGGCAGGAGGAAGCGGCGACCCTCCTCCACAGGATCAGAGGGTTGGTGCGCTGGGTCGTCGCCGAGGTCGCCGCCGGCCGCTCCCCGACCGTCGCGCTCCACCGCTACCAGAACTACTGCTCCTCCGCCTCCGCCGCCGCCGCGTCCCCATGCGCCTGCAGCTACGACGTCCCCGTGGGCACAGATGTACTCTCGCTCCTCCACCGGGGCTCCCACGCCTCCCGGCTCAATGTGCTCCTCAGGGTTCTTCTCGTCGTGCAGCAACTCCTGCAGCAGAACAAGCACTGCTCCAAGAGGGACATCTACTACATGTACCCCTCCATATTCCAAGAACAAGCGGTTGTTGACCGTGCAATCAATGATATATGCGTACTCTTCAAGTGCAGCCGGCACAATCTCAATGTGGTTCCTGTGGCAAAAGGCTTGGTGATGGGCTGGATTAGATTTTTAGAGGGAGAAAAGGAAGTCTATTGTGTAACGAATGTCAATGCTGCCTTCTCTATCCCAGTTAGCATCGAAGCAATAAAAGATGTTGTTAGTGTTGCGGACTACATACTTATTGTCGAGAAGGAGACAGTGTTTCAACGTTTGGCTAATGACAAGTTCTGTGAAAGGAATCGCTGCATTGTGATTACAGGAAGAGGCTACCCAGATATTCCAACAAGAAGATTCTTGCGCTACCTTGTTGAACAGCTGCATTTGCCAGTTTACTGTTTGGTGGATGCAGACCCTTATGGTTTCGACATTCTGGCTACCTACAAATTTGGTTCACTGCAATTGGCATACGATGCAAATTTCCTGCGTGTGCCTGATATTCGGTGGCTTGGGGTCTTCACATCTGATTTTGAGGATTATCGCCTTCCAGACTGCTGCCTACTTCACTTGTCGTCTGAAGACAGAAGGAAAGCTGAAGGAATTCTCTCAAGGTGTTACTTGCACAGGGAAGCCCCACAATGGAGGTTGGAGTTAGAAGCCATGTTGCAAAAGGGTGTCAAATTTGAGATTGAGGCGTTATCTGCATGTTCCATTTCCTTTTTATCAGAAGAGTACATTCCCAAGAAGATCAAACAAGGAAGACATATATAAGATTGGTTGTACCTGTATCTATCCAGAAATTTTCATGTGGCAAAAGTCTTATTTTGTTTTTGTCATGCTAACTGTAGTCACATGTATGGCACTCTGGTAGTTTAACCCCCAGCAAGTATTTTGTAGCAATTGTTTATATATGACGGTGATTTGGTGCTGTCTCAAGAACTGAAAACCACAAATTTACAGCAACTGAAATTTTACTA
CDS Sequence
- >LOC_Os03g54091.1
ATGGCGGGGAGGGAGAAGAGGCGGCGGGTGGCGGCGCTCGACGGCGAAGAGCGGCGGCGGCGGCAGGAGGAAGCGGCGACCCTCCTCCACAGGATCAGAGGGTTGGTGCGCTGGGTCGTCGCCGAGGTCGCCGCCGGCCGCTCCCCGACCGTCGCGCTCCACCGCTACCAGAACTACTGCTCCTCCGCCTCCGCCGCCGCCGCGTCCCCATGCGCCTGCAGCTACGACGTCCCCGTGGGCACAGATGTACTCTCGCTCCTCCACCGGGGCTCCCACGCCTCCCGGCTCAATGTGCTCCTCAGGGTTCTTCTCGTCGTGCAGCAACTCCTGCAGCAGAACAAGCACTGCTCCAAGAGGGACATCTACTACATGTACCCCTCCATATTCCAAGAACAAGCGGTTGTTGACCGTGCAATCAATGATATATGCGTACTCTTCAAGTGCAGCCGGCACAATCTCAATGTGGTTCCTGTGGCAAAAGGCTTGGTGATGGGCTGGATTAGATTTTTAGAGGGAGAAAAGGAAGTCTATTGTGTAACGAATGTCAATGCTGCCTTCTCTATCCCAGTTAGCATCGAAGCAATAAAAGATGTTGTTAGTGTTGCGGACTACATACTTATTGTCGAGAAGGAGACAGTGTTTCAACGTTTGGCTAATGACAAGTTCTGTGAAAGGAATCGCTGCATTGTGATTACAGGAAGAGGCTACCCAGATATTCCAACAAGAAGATTCTTGCGCTACCTTGTTGAACAGCTGCATTTGCCAGTTTACTGTTTGGTGGATGCAGACCCTTATGGTTTCGACATTCTGGCTACCTACAAATTTGGTTCACTGCAATTGGCATACGATGCAAATTTCCTGCGTGTGCCTGATATTCGGTGGCTTGGGGTCTTCACATCTGATTTTGAGGATTATCGCCTTCCAGACTGCTGCCTACTTCACTTGTCGTCTGAAGACAGAAGGAAAGCTGAAGGAATTCTCTCAAGGTGTTACTTGCACAGGGAAGCCCCACAATGGAGGTTGGAGTTAGAAGCCATGTTGCAAAAGGGTGTCAAATTTGAGATTGAGGCGTTATCTGCATGTTCCATTTCCTTTTTATCAGAAGAGTACATTCCCAAGAAGATCAAACAAGGAAGACATATATAA
Protein Sequence
- >LOC_Os03g54091.1
MAGREKRRRVAALDGEERRRRQEEAATLLHRIRGLVRWVVAEVAAGRSPTVALHRYQNYCSSASAAAASPCACSYDVPVGTDVLSLLHRGSHASRLNVLLRVLLVVQQLLQQNKHCSKRDIYYMYPSIFQEQAVVDRAINDICVLFKCSRHNLNVVPVAKGLVMGWIRFLEGEKEVYCVTNVNAAFSIPVSIEAIKDVVSVADYILIVEKETVFQRLANDKFCERNRCIVITGRGYPDIPTRRFLRYLVEQLHLPVYCLVDADPYGFDILATYKFGSLQLAYDANFLRVPDIRWLGVFTSDFEDYRLPDCCLLHLSSEDRRKAEGILSRCYLHREAPQWRLELEAMLQKGVKFEIEALSACSISFLSEEYIPKKIKQGRHI*