Information report for TIP3
Gene Details
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Functional Descriptions
- Map-based cloning demonstrated that TIP3 encodes a conserved PHD-finger protein and further study confirmed TIP3 functioned as a transcription factor with transcriptional activation activity.
- The TIP3 mutant displayed smaller and pale yellow anthers without mature pollen grains, abnormal Ubisch body morphology, no pollen wall formation as well as delayed tapetum degeneration.
- Moreover, TIP3 can physically interact with TDR which is a key component of the transcriptional cascade in regulating tapetum development and pollen wall formation.
- Taken together, our results reveal an unprecedented role of TIP3 in regulating Ubisch bodies and pollen exine formation, which presents a potential tool to manipulate male fertility for hybrid rice breeding.
- TIP3 is preferentially expressed in the tapetum and microspores during anther development.
- Furthermore, disruption of TIP3 changed the expression of several genes involved in tapetum development and degradation, biosynthesis and transport of lipid monomers of sporopollenin in TIP3 mutant.
Functional Keywords
Literature and News
Gene Resources
- UniProt: Q8W342
- EMBL: AP014959, DP000009
- AlphaFoldDB: Q8W342
- EnsemblPlants: Os03t0716200-01
- Gramene: Os03t0716200-01
- KEGG: osa:4333910
- Orthologous matrix: RCSGWSH
- InterPro: IPR001965, IPR011011, IPR013083
- PANTHER: PTHR46201, PTHR46201:SF9
- SUPFAM: SSF57903
- PROSITE: PS01359
- Gene3D: 3.30.40.10
- OrthoDB: Q8W342
- SWISS-MODEL: Q8W342
- Conserved Domain Database: cd15556
- eggNOG: KOG1844
Homologs
- Glycine max: MS3
Sequences
cDNA Sequence
- >LOC_Os03g50780.1
AAGGAGAGCCCAGGGCAATGCCGTCCATGCGCGCGCTCGAGCGGCTCGCCTCGTGGCCGACGCCCCCGCCGCCACCTCCGCCGCCGCCGCCGCCGGCGAAGGCGGCGGCGGCGGAGGCGGAGAGGCCGTGTCCGCCGTCGTCCGCCGCCACCACCTCGTCGTCGTCTTCTTCCTCGGCCTCGGCCGCGCCCGCGGCGGCGGGGGCGCCGCGCGTCTACCCGCTGCGGGACTTCCCGGGGAGGGAGGCGGCGGGGCTGGGCGGCGCGTTCCGGGACAACGTGCGGTGGCTGCTGAGGCAGTGGGGCGGCGCCTCCCCCGCCTCCCCCGCCGCCGGGGGTCCTGGGTCGGCGTCGGCGGCGGTGGCGGTGGCGTGGCGGGTGCTCCTCTCCGACGACCGCACCGGCGTCGTCGTCCCCATCTTCGCCGTCGAGGAGCCCGTCGCGTCCTCGCCCAAGCCGCTCTGCGATTACTGCCGCTGGGCGGGTTGGAGCCACCATTGGGTGTCAAAGCGGAAGTACCATTTCATTATTCCGGCGCCCGCTGACTGGGACCGCCAGCTTGCTGCTGATGTGATCCTTGGACGCACCGACCACCTCCTCCATGGCCTGATCCACAGCAATGGTTTTGGTCACCTTGTCATGCTCCGTGGTCGCGATGGCGGCTCCACTGCACTATCTGGCCGTGACATCATGGACATCTGGGATTGCCTCTGCTCCGCTCTTCGTGCCAGGGCTGTGTCTGTGGTGGACTTTTCCCAGAAACGCTCTCTGGATCTTCGTCTCCTGCTCAGCGTGGCACATGGTGACACATGGTTCACCCGATGGGGATACTGCCTTGCAAGGGGTTGCTTCTGTGTGTCTACCTCGACCTATGCAGCTTCCGTGGAAGCGTTGGCTGCCCTGCCTGTGGACTATCTTCGCAGCCGTCACGTCCGCCGTGTGGTAACCATTTACCGCCGCCTATCCAACAAACCTCTGGTTACAGTCCGTGAGTTCCTCCGCTGCCTCCTTGATTGGAAGCACCTTGAGCCACCCCTTCAATTACCTCCTGTGAAGACATGCACACGGCTGCAATTCATGCTGCCAAAGCCATCTGTGATGAAGAGACACAGGCAGCAGCCATGCCAGCGCTTTGAGGATGTGATTGACCTGCTCCAGTGTCGCTGGTCCAAGAAGCGGCTTCTTGATGCTGCAGAGGTTGTTGTTGACAGGCTGCTAGAGCATGGCAGCGGGGCAGAGATGACACGGCAGGCGGTGCGAGATGCTGCAAGGGGCGCCATTGGTGATACTGGTCTCCTTGACTTTGTCATCAAGTCCCTTGGTGATACCATTGTTGGCAACTATATTGTGCGACGTGTGCCTGATGCTGAAACACGTGTGCTTCACTTTAGCCTTGAGGAATATGAAGAGCCAACACCAGCACTGTTGGATGTTGAGGTAGAGTGCACACCATTGCCACCTGTGGTACGGTGGCCTAGCACAGTGGAAGTAGAGCGAGATCTGCGTGCTGTCTACCGAGCAATGGTCGAGGTGCGCAGTGAGGCAGCACAGGCTGTGCTGGACTGCAAGCACTGGGTGAAGTGGTGGGGCCTTGGGGATGAGTCCGATGACCAGCTGAGGTTTTTCGTTGAGTGGCAACCCCAGCCATGGGAAGCTGCTGAGCTTATACGGCCAATGCCACTGGGGGAGATTGTGGTGGTACCACTCCATGCATCCATGGGTGAGCTTCTTGTCGAGTCAGAGCATGCGCTGCGGGACACTTACTACTTCTTTGAGGAATTCCAGGCTGAAGGGCTGCATGGCATTGCTGGGGAGAAATGGGATCCAGTGATGCTTGGTGGGGCAGAGAATGGTGACACAATCAGCGTGTATGGCAATGGGGCAGACATGGAAACTGAGCTGCGGTGCCATGGTGGACTTGACTTGTGGGAGGTGCGGTGCGTGTGTGGTGCGCAGGATGATGATGGTGAGCGCATGATAGCATGCGATGCTTGCGATGTATGGCACCACACACGTTGCGTGGGCATTGCAGACAGCGAGCCTGTGCCACCATTATTTCTTTGTGTGCTCTGCGGTGGTGCGCTCATGGCGGCTGGACCGATCAATTCTTGAAGAGGCACTAACGCTACCTGAAAGCCAAGTGACTATTCTATTCTTTTCCCCTTTCTTACTTCCCTTCGGTTCATATTTCCAGTGACGATAGTCTGACGAGGTAAACTTAGTTCTGAAACTGCAACTTATGGTGTAAAGTGCGTTGTTTTGGCAGTATGTAGTAACTTCTAATGCTGTGTAGTAAGTAGTAGATGGGAAGCGGGTTTAGACAGTAGACTTGGGGAAGCCCTATCCATGTCGTTAGCAATTCGACTGGAAATTTTGTACCTGATACACTACAGAAGATGATATAGCTAGATGTAAATACATGTTCTGTGATTGTATCTTTTACGGCCTCCCAGTCCCAATTGGTGAAGCTATACAGTGTAATTTTTTGTGCTAGGTATACAATGTAATTTAGCATCAGCAATGACAAAACTGTATCTTTCTTCTGTGCTGGTGTTTGCTTTCTTGTTAGCCA
CDS Sequence
- >LOC_Os03g50780.1
ATGCCGTCCATGCGCGCGCTCGAGCGGCTCGCCTCGTGGCCGACGCCCCCGCCGCCACCTCCGCCGCCGCCGCCGCCGGCGAAGGCGGCGGCGGCGGAGGCGGAGAGGCCGTGTCCGCCGTCGTCCGCCGCCACCACCTCGTCGTCGTCTTCTTCCTCGGCCTCGGCCGCGCCCGCGGCGGCGGGGGCGCCGCGCGTCTACCCGCTGCGGGACTTCCCGGGGAGGGAGGCGGCGGGGCTGGGCGGCGCGTTCCGGGACAACGTGCGGTGGCTGCTGAGGCAGTGGGGCGGCGCCTCCCCCGCCTCCCCCGCCGCCGGGGGTCCTGGGTCGGCGTCGGCGGCGGTGGCGGTGGCGTGGCGGGTGCTCCTCTCCGACGACCGCACCGGCGTCGTCGTCCCCATCTTCGCCGTCGAGGAGCCCGTCGCGTCCTCGCCCAAGCCGCTCTGCGATTACTGCCGCTGGGCGGGTTGGAGCCACCATTGGGTGTCAAAGCGGAAGTACCATTTCATTATTCCGGCGCCCGCTGACTGGGACCGCCAGCTTGCTGCTGATGTGATCCTTGGACGCACCGACCACCTCCTCCATGGCCTGATCCACAGCAATGGTTTTGGTCACCTTGTCATGCTCCGTGGTCGCGATGGCGGCTCCACTGCACTATCTGGCCGTGACATCATGGACATCTGGGATTGCCTCTGCTCCGCTCTTCGTGCCAGGGCTGTGTCTGTGGTGGACTTTTCCCAGAAACGCTCTCTGGATCTTCGTCTCCTGCTCAGCGTGGCACATGGTGACACATGGTTCACCCGATGGGGATACTGCCTTGCAAGGGGTTGCTTCTGTGTGTCTACCTCGACCTATGCAGCTTCCGTGGAAGCGTTGGCTGCCCTGCCTGTGGACTATCTTCGCAGCCGTCACGTCCGCCGTGTGGTAACCATTTACCGCCGCCTATCCAACAAACCTCTGGTTACAGTCCGTGAGTTCCTCCGCTGCCTCCTTGATTGGAAGCACCTTGAGCCACCCCTTCAATTACCTCCTGTGAAGACATGCACACGGCTGCAATTCATGCTGCCAAAGCCATCTGTGATGAAGAGACACAGGCAGCAGCCATGCCAGCGCTTTGAGGATGTGATTGACCTGCTCCAGTGTCGCTGGTCCAAGAAGCGGCTTCTTGATGCTGCAGAGGTTGTTGTTGACAGGCTGCTAGAGCATGGCAGCGGGGCAGAGATGACACGGCAGGCGGTGCGAGATGCTGCAAGGGGCGCCATTGGTGATACTGGTCTCCTTGACTTTGTCATCAAGTCCCTTGGTGATACCATTGTTGGCAACTATATTGTGCGACGTGTGCCTGATGCTGAAACACGTGTGCTTCACTTTAGCCTTGAGGAATATGAAGAGCCAACACCAGCACTGTTGGATGTTGAGGTAGAGTGCACACCATTGCCACCTGTGGTACGGTGGCCTAGCACAGTGGAAGTAGAGCGAGATCTGCGTGCTGTCTACCGAGCAATGGTCGAGGTGCGCAGTGAGGCAGCACAGGCTGTGCTGGACTGCAAGCACTGGGTGAAGTGGTGGGGCCTTGGGGATGAGTCCGATGACCAGCTGAGGTTTTTCGTTGAGTGGCAACCCCAGCCATGGGAAGCTGCTGAGCTTATACGGCCAATGCCACTGGGGGAGATTGTGGTGGTACCACTCCATGCATCCATGGGTGAGCTTCTTGTCGAGTCAGAGCATGCGCTGCGGGACACTTACTACTTCTTTGAGGAATTCCAGGCTGAAGGGCTGCATGGCATTGCTGGGGAGAAATGGGATCCAGTGATGCTTGGTGGGGCAGAGAATGGTGACACAATCAGCGTGTATGGCAATGGGGCAGACATGGAAACTGAGCTGCGGTGCCATGGTGGACTTGACTTGTGGGAGGTGCGGTGCGTGTGTGGTGCGCAGGATGATGATGGTGAGCGCATGATAGCATGCGATGCTTGCGATGTATGGCACCACACACGTTGCGTGGGCATTGCAGACAGCGAGCCTGTGCCACCATTATTTCTTTGTGTGCTCTGCGGTGGTGCGCTCATGGCGGCTGGACCGATCAATTCTTGA
Protein Sequence
- >LOC_Os03g50780.1
MPSMRALERLASWPTPPPPPPPPPPPAKAAAAEAERPCPPSSAATTSSSSSSSASAAPAAAGAPRVYPLRDFPGREAAGLGGAFRDNVRWLLRQWGGASPASPAAGGPGSASAAVAVAWRVLLSDDRTGVVVPIFAVEEPVASSPKPLCDYCRWAGWSHHWVSKRKYHFIIPAPADWDRQLAADVILGRTDHLLHGLIHSNGFGHLVMLRGRDGGSTALSGRDIMDIWDCLCSALRARAVSVVDFSQKRSLDLRLLLSVAHGDTWFTRWGYCLARGCFCVSTSTYAASVEALAALPVDYLRSRHVRRVVTIYRRLSNKPLVTVREFLRCLLDWKHLEPPLQLPPVKTCTRLQFMLPKPSVMKRHRQQPCQRFEDVIDLLQCRWSKKRLLDAAEVVVDRLLEHGSGAEMTRQAVRDAARGAIGDTGLLDFVIKSLGDTIVGNYIVRRVPDAETRVLHFSLEEYEEPTPALLDVEVECTPLPPVVRWPSTVEVERDLRAVYRAMVEVRSEAAQAVLDCKHWVKWWGLGDESDDQLRFFVEWQPQPWEAAELIRPMPLGEIVVVPLHASMGELLVESEHALRDTYYFFEEFQAEGLHGIAGEKWDPVMLGGAENGDTISVYGNGADMETELRCHGGLDLWEVRCVCGAQDDDGERMIACDACDVWHHTRCVGIADSEPVPPLFLCVLCGGALMAAGPINS*