Gene Details:
- MSU gene ID: LOC_Os03g46330
- RAPdb gene ID: Os03g0666100
- Gene Symbol: CRL4 OsGNOM1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- RT-PCR and analysis of promoter::GUS transgenic plants showed that OsGNOM1 is expressed in AR primordia, vascular tissues, LRs, root tips, leaves, anthers and lemma veins, with a distribution pattern similar to that of auxin.
- ) mutant crown rootless4 (CRL4) that was found to have defective crown root formation.
- Besides reduced crown root number, the CRL4 mutant showed auxin-related abnormal phenotypical character-istics such as reduced lateral root number and impaired root gravitropism.
- These results indicate that maintaining an appropriate auxin accumulation and gradient through CRL4 in the basal portion of shoots is essential for crown root formation in rice.
- CRL4 regulates crown root formation through auxin transport in rice.
- CRL4 encodes a protein highly homologous with Arabidopsis GNOM, which mediates auxin-dependent plant growth by coordinating the polar localization of auxin efflux carrier PIN1.
- In the CRL4 mutant, auxin transport was impaired in shoots and roots.
- Adventitious root formation in rice requires OsGNOM1 and is mediated by the OsPINs family.
Function-related keywords:
- anther , crown-root , lemma , auxin , growth , shoot , root , adventitious-root , lateral-root , crown
Literature:
- CRL4 regulates crown root formation through auxin transport in rice . DOI: 10.3117/plantroot.2.19
- Adventitious root formation in rice requires OsGNOM1 and is mediated by the OsPINs family . DOI: 10.1038/cr.2009.70 ; PMID: 19546891
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os03g46330.1
ATGAACCTCACTTCACTATGCTGTGCTGGCCTGCTCAAATGAATATTGGTATGACACGTTTGGTAGGTTTTAGAAATAGTGGAAGTTTTTTTTTTCCTTTTTCCCTTTCCCCTGCATTTTGTAAAATAGAATGCGCAAACATGCTGAATCCGATAACACTATCTGGCTACCTGCATGTGTGACTGCTTTATTATTTTCTTTTCGAACTCGGAAAACAACCATGTTTTGTTTTCACTGCACCAATATCTTCTGTTCAATCCATCCTCAAAATTCTCCTTTAAAGTAGGCCGTATTCAGTTGGTTTTATAATCATTTATTCAAAAAGTGGGTCTATCGATGTTTCCCTGTTCCTTCCAAACCCAGTTTCCAGTTTGTTCTCCCTCAGGAACCAGTTTTAAAACTGGATTGTTGAGGCTGGTGATGTTTTGAAATCAGGACCATGTACTTGATGGTTACTTTGATAAATGTCAGTGACTTCTTTTCCAATATTCAGTTTCAATACCTCGAAACTGTCGTGCAAGTGTGGTATGTTTTTATGCGATGCACTATGTTGTTGCTGAGGTCTGCAATGTGCATGTTTATCCCAAGATTTTAGTCACTATTCTGCTATGCCTGTTTCTAACCAACTGATATGCTTCTCAACTCTTCATTTGCAAATTTGACAGAGAATTTGTAGTTTGTAAGCTCAAAACAGTAGTTCCTCACTTGGGAACCACTTACTCAGAAACAGTAACAATAAATAATGTTTGAACAGTCCAAGTTCCCAACAAATTACCATATTTTTTATTGCGTTTAGCATGGAACTGATTGGAATCAGGAGATCTTGAAACGAATTGGAGGTCATAGGGATAAACCTAGCTCCACGAAGAGAATTAGAGATATCCACTACCTCACTGGAAGTATAAAATAGTAGTTTTTCTCATCTCACCATAGATTTCCTACCCTTATCTGAAGGGACACACTTGATGTGCACAAACAGAACTTGTGCATGATGAAATGTTAAAGTTTCTGACAAATACCAAATTATGTTGTTTCAACTTTATTTAAGTTTGACACAAGACCTGGTATCCATTATTTTATTCCATAATCTGGTTGGGATAATTGCTTTCTGCTGTTTTCTTTTTACTTTTTTTTAATCCCTAGTCCCAATGGTGTTTTAATTTATGAATGCAGACATGGTGATCTAACACCATAATCATAAGGGCCTTGTTATCACCAGCACTTCTACAACCTCAATGACACAGCCATGCTCAGCCTAAATGGTTTTGCTTGGACACTTCTGGTTACCTTGCATCTTTTAGCTCACCCGCTGTATCTTGCATGCTGTGTTGCCAAGTCTTTTTGTTGAGCAAAACAAAGTCGTAAAGGTGGCCTTTTTTAGTGCCTGTCAACTGTTTTAGTGAAAGGCCGTCTAGAAGGTTGTCAACATTAAAGATATGTAGTGATTAAGAGTACACAGAAAAACCTTCAGCCCAATCATGTGTTTGGATTTATGGTAAGGTGAAAAATTTGGCTACTTTTGTACTACTATTAATGAATCCATCTCAAGTTATGTCCAGGTAAAATAAAATTTTAGTGCTGAAAGGGTCCATAAAAGTCTTACAAAACACATTTGTATTAATTTCCCTATCATGTTTACAACATGGCGCAGGTTTACCTAGTGCTTTTTGTATGCTACTTGTGCAGATGGGTGGCATGGATAAAAACCATCCTTTTGGGATTGGACAAATGGAAAATGGCAATGGGAGCTATGCATCTGAGGCAGTTACATCTGATGAGAATTCTGCAGATGGCAGTGGCATTGTTGTGGAGCCTTACGGGATCCCATGCATGGTGGAGATTTTTCATTTCCTCTGCTCCCTCCTCAATGTTGTCGAGCAAATTGGAGTTGATGAAGATCTGCCATTGTTTGCTCTGAAGTTGATCAATTCAGCAATTGAGCTTGGTGGATCTTCAATTCGTAAGCACCCAAAATTGCTGTCATTAGTTCAAGATGAGCTTTTCCGAAACCTAATGCAGTTTGGGTTGTCCATGAGCCCACTTATCCTTTCAATGGTGTGCAGCATTGTGCTAAATCTTTATCATCATCTCCGGACTGAGCTCAAATTGCAGCTTGAGGCATTCTTTTCTTGTATAATCCTAAGGCTTGCACAACCCCGATTCGGAGCAACATATCATCAGCAGGAGGTTGCAATGGAAGCTCTTGTTGATTTTTGTCGACAAAAGAATTTCATGGTGGAGATGTATGCCAATCTGGACTGTGACATAACCTGCAGGAATATTTTTGAGGAACTTGCAAATCTTCTGTCAAAGAGTGCATTTCCTATTAACTGCCCATTGTCTTCCATGCACATTCTTGCTCTGGAAGGTCTGATCTCTGTGATCCAAGGGATGGCTGATCGGATTGGGAATGCTACTTCACGCCCTGAGCTCCTGCCTGTGGAGCTTGATGAATACACTCCCTTCTGGACTGTTAAGTGTGAGAATTTTTCAGATCCTCAGCATTGGGTGAAGTTTGTCCGTCAAAGAAAGTATGTCAAAAGAAGACTAATGATTGGTGCTGATCACTTCAACAGAGACCCAAAGAAGGGTCTGGAATTTCTTCAAGGCACTCATTTGTTGCCTGAGAAGCTTGATCCCCAAAGTGTGGCTTGTTTTTTCCGCTATACAGCTGGTTTGGACAAGAATCTTGTAGGAGACTTTCTAGGCAATCATGATGAGTTTTGTGTTCAGGTGCTTCATGAGTTTGCTCAAACCTTTGACTTCCAGGAGATGAACCTTGATACAGCTCTGAGACTATTTTTGGAGACATTTCGTCTGCCTGGAGAATCTCAGAAGATACAGAGGGTTCTTGAGGCTTTCTCAGACAGATACTATGAGCAGTCCCCACAGGCTTTCGCAAACAAGGACACTGCTTTAGTGCTTGCTTACTCAATTATAATGCTGAACACTGATCAGCATAACATGCAAGTAAAGAAGAAAATGACTGAGGAGGACTTCATCAAGAACAACAGGAACATAAATGGGGGTAGTGACCTTCCGCGTGAGATGCTGTCTGAACTATACCACTCCATATGCCGAAATGAGATTAAGACCACACCAGAGCAGGGTATGGGATATTTTGAAATGTCTCCCAGCCGCTGGATAGATTTAATGCGGAAGTCGAAGTCAACATCTCTGTATATAGTTGGTGATTCTCAGCCCTTTCTGGATCATGATATGTTTGCTATCATGTCTGGTCCTACTATTGCTGCCATTGCAGTGGTGTTTGATCATTCGGAACATGAAGAAGTTCTGTTGGCCTGTGTGGATGGCTTCTTGGGTGTCGCAAAAATCTCAGCATTTCATCATCTTGAAGATGTTTTGGATGATCTTGTCGTTTCTCTCTGCAAATTCACCACTCTTTTAAACACCTCTTTGGTTGAGGAACCAGTTACTGCCTTTGGGGATGACCTGAAGGCTAGATTGGCAACTGAGACATTGTTTACCATAGCTAATAGATATGGGGACTACATACGTACTGGCTGGAGGAATGTTTTGGATTGCATATTGAGGCTGCATAAGTTAGGCCTTCTTCCTGCCCGTGTTGCTAGTGATGCAGCTGATGATTCAGAAGTTTCTGCTGAAACTGTCCAAGGAAAGCCTACTCATAGCTCAATTTCCACATCTCATATTCCAGTTATGGGTACGCCTCGGAAATCCTCTGGACTTATGGGGAGATTTAGTCAGCTGCTGTCACTTGACAGCGAAGAACCAAGGTCACAGCCCACTGAGCAGCAACTTGCTGCCCATCAGAGAACTCTACAGACGATTCAGAAATGCCGAATAGATAGTATATTTACAGAGAGCAAATTCTTGCAACCTGATTCACTATTACAACTTGCTAGGGCACTGATTTGGGCTGCAGGACGACCTCAAAAGGTTGCCAGCTCACCAGATGATGAGGACACAGCTGTATTCTGTCTGGAACTGCTAATCGCAATTACGCTTAACAACCGAGACCGAATTGTGCTTCTCTGGCAAGGAGTTTATGAGCATATTGCCAACATAGTTCAGTCAACAGTTATGCCATGTGCTCTTGTGGAGAAAGCTATTTTTGGACTTCTGCGCATATGCCAGAGGTTATTACCATATAAAGAGAACCTTGCGGATGAGCTGCTGAGGTCATTGCAATTAGTTCTCAAGCTGGATGCGCGTGTAGCAGATGCATACTGTGAAAACATCACTCAGGAGGTTGCACGCCTTGTCAAAGCAAATGCTGGACACGTAAAATCACAAATGGGCTGGAGAACTGTAGTGTTACTGCTCTCCATTACAGCTCGACACCCTGATGCTTCAGAAGTAGGCTTTGAGGCTATCATGTATATCATGTCCGAGGGTGCTCACCTTTCACTATCAAATTATGCTTTCTGTATCGAAGCGTCACGGCAGTTTGCTGAATCCAGGGTTGGTCTAATTGACAGATCCATTCGTGCCCTGGATCTGATGGCTGATTCAGCCAATAGTCTTGCCCGATGGTCACAAGAGACAAAAGGGACAGGCGAGGAAACTGACAAAGTGTTGGAAGCAATCAGGGAGATGTGGCTCAAATTGCTGCAAGCACTGAAAAAGTTGAGTTTGGATCAGAGAGAGGAGGTGAGAAATCACGCGCTAACTTCGCTTCAGCGATGCCTAACAGCAACAGAAGGGGTGTGCCTTCAGAGCTCCACATGGTCACATGCTTTCGATCTCGTCATATTCGCGCTGCTGGATGACTTACTAGAGATCAGCCAGAATCACTCGCAGAAGGACTACAGGAACATGGAAGGATCCCTTGTGCTCGCCATGAAACTAGTCGCGAAGGTCTATCTGCAACTACTGCCAGATCTTTTTGGGCTAAGCAGCTTCTGCAAGTTGTGGCTAGGAGTCCTCAGCCGGATGGAGAAGTACATCAAGATCAAGGTCCGTGGCAAGCGCAGCGACAAGCTGCAAGAGCTGATCCCTGAGCTGCTCAAGAACATTCTAATTGCGATGAAGAACAGGGGGATCCTCGCAAAGAGGAGCACCATTGGGGGCGACAGCTTGTGGGAGTTGACATGGCTTCATGCGAATAACATCTCGACGAGTTTGCAGTCTGATGTTTTCCCAAGCCAGGAGTATGAGCAGCACAGCAGTGCCGGTAGCCCGAGAGGACCCAACGGCGTTGAGTCCCGGGACTAGAAAGTTCAGAAGTTCAGGTGGTGATGGCTGGTTGATGGTTCGGCGTGCCGTGGAGTGTGCAAGTTTAGTTATTATGTTACTAGGTTTACCAATTGCTTGCTTTCTTATCCACTGAAACGTAAGGTTTTGATATTGTAATTGCAATGCGTGCCCCCATTGTAAGTTGATCTTGTAAGTTTTGTAGTAGTATTCTGGCGAGCTCGCGGACCAGTTTTTACAGTCCTTGTTTGGAGTTGCTGATGTTCCGTGTAAAGGGAAACCGTGACAGCAATGTGACCAAGTTGACAAGATCTCACATTCACACTGCTAATCTGCCGTTTTAACAGTTACTACTACTTTAATGCATTGAAGTCAGAATGTAACAAAAGAGAGCTTGAACCGAACAATTTACACACACAAGCCACCGCTATCTTTTATTTGAGTCGTATAGTTTTAATACAATGAACATACAACCAGGCACCGGTGCGAACTCCTGCCACAGCAATTCTCGAAAGGATTCAAATCCCAGTCGGTTATCCTCAATAATCACAACAATCCCAGAATGTATTTGGCTCCAGGCCTTCAGGGGTGGGTTGCGCCTCCCTGGATATGATCGCTCACTGGTGGGGGGTTGACCACAGGGATATCCAAGCTGCCGCCTTCTGATTCTGGGGAGACCTCCCGCACATCGGCGATCAATGCTTCCGACTGCTGGAAACTACCCCACTCCGCATCACCGATAGGACGGATGTCGACCCCATCCACGGCCAGTTGGACTTCAGTGTTATCATTGGAAACTAGGACAGATCTTGAGTCACTCACACAAGCTTTGTCGACATCGTCATCTGATGCATCGACGTGCTTTGTCAAGGGAGGGGAGTTATCGGTGCCGGAGCATGATTCAGATCTCTCTTCGCATACCTGCTTCGTGCTGCTTTGCTCTCT
CDS Sequence
- >LOC_Os03g46330.1
ATGCTACTTGTGCAGATGGGTGGCATGGATAAAAACCATCCTTTTGGGATTGGACAAATGGAAAATGGCAATGGGAGCTATGCATCTGAGGCAGTTACATCTGATGAGAATTCTGCAGATGGCAGTGGCATTGTTGTGGAGCCTTACGGGATCCCATGCATGGTGGAGATTTTTCATTTCCTCTGCTCCCTCCTCAATGTTGTCGAGCAAATTGGAGTTGATGAAGATCTGCCATTGTTTGCTCTGAAGTTGATCAATTCAGCAATTGAGCTTGGTGGATCTTCAATTCGTAAGCACCCAAAATTGCTGTCATTAGTTCAAGATGAGCTTTTCCGAAACCTAATGCAGTTTGGGTTGTCCATGAGCCCACTTATCCTTTCAATGGTGTGCAGCATTGTGCTAAATCTTTATCATCATCTCCGGACTGAGCTCAAATTGCAGCTTGAGGCATTCTTTTCTTGTATAATCCTAAGGCTTGCACAACCCCGATTCGGAGCAACATATCATCAGCAGGAGGTTGCAATGGAAGCTCTTGTTGATTTTTGTCGACAAAAGAATTTCATGGTGGAGATGTATGCCAATCTGGACTGTGACATAACCTGCAGGAATATTTTTGAGGAACTTGCAAATCTTCTGTCAAAGAGTGCATTTCCTATTAACTGCCCATTGTCTTCCATGCACATTCTTGCTCTGGAAGGTCTGATCTCTGTGATCCAAGGGATGGCTGATCGGATTGGGAATGCTACTTCACGCCCTGAGCTCCTGCCTGTGGAGCTTGATGAATACACTCCCTTCTGGACTGTTAAGTGTGAGAATTTTTCAGATCCTCAGCATTGGGTGAAGTTTGTCCGTCAAAGAAAGTATGTCAAAAGAAGACTAATGATTGGTGCTGATCACTTCAACAGAGACCCAAAGAAGGGTCTGGAATTTCTTCAAGGCACTCATTTGTTGCCTGAGAAGCTTGATCCCCAAAGTGTGGCTTGTTTTTTCCGCTATACAGCTGGTTTGGACAAGAATCTTGTAGGAGACTTTCTAGGCAATCATGATGAGTTTTGTGTTCAGGTGCTTCATGAGTTTGCTCAAACCTTTGACTTCCAGGAGATGAACCTTGATACAGCTCTGAGACTATTTTTGGAGACATTTCGTCTGCCTGGAGAATCTCAGAAGATACAGAGGGTTCTTGAGGCTTTCTCAGACAGATACTATGAGCAGTCCCCACAGGCTTTCGCAAACAAGGACACTGCTTTAGTGCTTGCTTACTCAATTATAATGCTGAACACTGATCAGCATAACATGCAAGTAAAGAAGAAAATGACTGAGGAGGACTTCATCAAGAACAACAGGAACATAAATGGGGGTAGTGACCTTCCGCGTGAGATGCTGTCTGAACTATACCACTCCATATGCCGAAATGAGATTAAGACCACACCAGAGCAGGGTATGGGATATTTTGAAATGTCTCCCAGCCGCTGGATAGATTTAATGCGGAAGTCGAAGTCAACATCTCTGTATATAGTTGGTGATTCTCAGCCCTTTCTGGATCATGATATGTTTGCTATCATGTCTGGTCCTACTATTGCTGCCATTGCAGTGGTGTTTGATCATTCGGAACATGAAGAAGTTCTGTTGGCCTGTGTGGATGGCTTCTTGGGTGTCGCAAAAATCTCAGCATTTCATCATCTTGAAGATGTTTTGGATGATCTTGTCGTTTCTCTCTGCAAATTCACCACTCTTTTAAACACCTCTTTGGTTGAGGAACCAGTTACTGCCTTTGGGGATGACCTGAAGGCTAGATTGGCAACTGAGACATTGTTTACCATAGCTAATAGATATGGGGACTACATACGTACTGGCTGGAGGAATGTTTTGGATTGCATATTGAGGCTGCATAAGTTAGGCCTTCTTCCTGCCCGTGTTGCTAGTGATGCAGCTGATGATTCAGAAGTTTCTGCTGAAACTGTCCAAGGAAAGCCTACTCATAGCTCAATTTCCACATCTCATATTCCAGTTATGGGTACGCCTCGGAAATCCTCTGGACTTATGGGGAGATTTAGTCAGCTGCTGTCACTTGACAGCGAAGAACCAAGGTCACAGCCCACTGAGCAGCAACTTGCTGCCCATCAGAGAACTCTACAGACGATTCAGAAATGCCGAATAGATAGTATATTTACAGAGAGCAAATTCTTGCAACCTGATTCACTATTACAACTTGCTAGGGCACTGATTTGGGCTGCAGGACGACCTCAAAAGGTTGCCAGCTCACCAGATGATGAGGACACAGCTGTATTCTGTCTGGAACTGCTAATCGCAATTACGCTTAACAACCGAGACCGAATTGTGCTTCTCTGGCAAGGAGTTTATGAGCATATTGCCAACATAGTTCAGTCAACAGTTATGCCATGTGCTCTTGTGGAGAAAGCTATTTTTGGACTTCTGCGCATATGCCAGAGGTTATTACCATATAAAGAGAACCTTGCGGATGAGCTGCTGAGGTCATTGCAATTAGTTCTCAAGCTGGATGCGCGTGTAGCAGATGCATACTGTGAAAACATCACTCAGGAGGTTGCACGCCTTGTCAAAGCAAATGCTGGACACGTAAAATCACAAATGGGCTGGAGAACTGTAGTGTTACTGCTCTCCATTACAGCTCGACACCCTGATGCTTCAGAAGTAGGCTTTGAGGCTATCATGTATATCATGTCCGAGGGTGCTCACCTTTCACTATCAAATTATGCTTTCTGTATCGAAGCGTCACGGCAGTTTGCTGAATCCAGGGTTGGTCTAATTGACAGATCCATTCGTGCCCTGGATCTGATGGCTGATTCAGCCAATAGTCTTGCCCGATGGTCACAAGAGACAAAAGGGACAGGCGAGGAAACTGACAAAGTGTTGGAAGCAATCAGGGAGATGTGGCTCAAATTGCTGCAAGCACTGAAAAAGTTGAGTTTGGATCAGAGAGAGGAGGTGAGAAATCACGCGCTAACTTCGCTTCAGCGATGCCTAACAGCAACAGAAGGGGTGTGCCTTCAGAGCTCCACATGGTCACATGCTTTCGATCTCGTCATATTCGCGCTGCTGGATGACTTACTAGAGATCAGCCAGAATCACTCGCAGAAGGACTACAGGAACATGGAAGGATCCCTTGTGCTCGCCATGAAACTAGTCGCGAAGGTCTATCTGCAACTACTGCCAGATCTTTTTGGGCTAAGCAGCTTCTGCAAGTTGTGGCTAGGAGTCCTCAGCCGGATGGAGAAGTACATCAAGATCAAGGTCCGTGGCAAGCGCAGCGACAAGCTGCAAGAGCTGATCCCTGAGCTGCTCAAGAACATTCTAATTGCGATGAAGAACAGGGGGATCCTCGCAAAGAGGAGCACCATTGGGGGCGACAGCTTGTGGGAGTTGACATGGCTTCATGCGAATAACATCTCGACGAGTTTGCAGTCTGATGTTTTCCCAAGCCAGGAGTATGAGCAGCACAGCAGTGCCGGTAGCCCGAGAGGACCCAACGGCGTTGAGTCCCGGGACTAG
Protein Sequence
- >LOC_Os03g46330.1
MLLVQMGGMDKNHPFGIGQMENGNGSYASEAVTSDENSADGSGIVVEPYGIPCMVEIFHFLCSLLNVVEQIGVDEDLPLFALKLINSAIELGGSSIRKHPKLLSLVQDELFRNLMQFGLSMSPLILSMVCSIVLNLYHHLRTELKLQLEAFFSCIILRLAQPRFGATYHQQEVAMEALVDFCRQKNFMVEMYANLDCDITCRNIFEELANLLSKSAFPINCPLSSMHILALEGLISVIQGMADRIGNATSRPELLPVELDEYTPFWTVKCENFSDPQHWVKFVRQRKYVKRRLMIGADHFNRDPKKGLEFLQGTHLLPEKLDPQSVACFFRYTAGLDKNLVGDFLGNHDEFCVQVLHEFAQTFDFQEMNLDTALRLFLETFRLPGESQKIQRVLEAFSDRYYEQSPQAFANKDTALVLAYSIIMLNTDQHNMQVKKKMTEEDFIKNNRNINGGSDLPREMLSELYHSICRNEIKTTPEQGMGYFEMSPSRWIDLMRKSKSTSLYIVGDSQPFLDHDMFAIMSGPTIAAIAVVFDHSEHEEVLLACVDGFLGVAKISAFHHLEDVLDDLVVSLCKFTTLLNTSLVEEPVTAFGDDLKARLATETLFTIANRYGDYIRTGWRNVLDCILRLHKLGLLPARVASDAADDSEVSAETVQGKPTHSSISTSHIPVMGTPRKSSGLMGRFSQLLSLDSEEPRSQPTEQQLAAHQRTLQTIQKCRIDSIFTESKFLQPDSLLQLARALIWAAGRPQKVASSPDDEDTAVFCLELLIAITLNNRDRIVLLWQGVYEHIANIVQSTVMPCALVEKAIFGLLRICQRLLPYKENLADELLRSLQLVLKLDARVADAYCENITQEVARLVKANAGHVKSQMGWRTVVLLLSITARHPDASEVGFEAIMYIMSEGAHLSLSNYAFCIEASRQFAESRVGLIDRSIRALDLMADSANSLARWSQETKGTGEETDKVLEAIREMWLKLLQALKKLSLDQREEVRNHALTSLQRCLTATEGVCLQSSTWSHAFDLVIFALLDDLLEISQNHSQKDYRNMEGSLVLAMKLVAKVYLQLLPDLFGLSSFCKLWLGVLSRMEKYIKIKVRGKRSDKLQELIPELLKNILIAMKNRGILAKRSTIGGDSLWELTWLHANNISTSLQSDVFPSQEYEQHSSAGSPRGPNGVESRD*