Gene Details:
- MSU gene ID: LOC_Os03g40550
- RAPdb gene ID: Os03g0602600
- Gene Symbol: OsFLN2 HSA1 GRA117
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Map-based cloning revealed that HSA1 encodes a putative OsFLN2.
- The HSA1 mutant harbors a recessive mutation in a gene encoding fructokinase-like protein2 (FLN2); the mutation causes a premature stop codon and results in a severe albino phenotype, with defects in early chloroplast development.
- The color of HSA1 mutant plants gradually changed from albino to green at later stages of development at various temperatures and chloroplast biogenesis was strongly delayed at high temperature (32<U+202F>
C). - HSA1 localizes to the chloroplast and regulates chloroplast development.
- These results demonstrated that HSA1 plays important roles in chloroplast development at early stages, and functions in protecting chloroplasts under heat stress at later stages in rice.
- GRA117 encodes PfkB-type fructokinase-like 2, which is subcellularly localized in chloroplasts and is widely expressed in various rice tissues, particularly at high levels in leaf tissues.
- RNA-Seq analysis revealed that GRA117 plays a significant role in photosynthetic carbon fixation, carbon metabolism, and chloroplast ribosome-related pathways.
- Our study supports that GRA117 promotes the Calvin-Benson cycle by regulating chloroplast development, ultimately leading to enhanced carbon assimilation in rice.
- GRA117 is crucial in the process of carbon assimilation in rice as it regulates the development of chloroplasts, which in turn facilitates the Calvin-Benson cycle.
Function-related keywords:
- map-based-cloning , chloroplast , temperature , development , stress , chloroplast-development , leaf
Literature:
- FRUCTOKINASE-LIKE PROTEIN 1 interacts with TRXz to regulate chloroplast development in rice . DOI: 10.1111/jipb.12631 ; PMID: 29319227
- The newly identified heat-stress sensitive albino 1 gene affects chloroplast development in rice . DOI: 10.1016/j.plantsci.2017.11.015 ; PMID: 29362095
- Characterization of dwarf and narrow leaf (dnl-4) mutant in rice . DOI: 10.1080/15592324.2020.1849490 ; PMID: 33300429
- A natural variation in the promoter of GRA117 affects carbon assimilation in rice . DOI: 10.1007/s00425-023-04109-z ; PMID: 36894728
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os03g40550.1
CTGCTCAGCTCTGAGCTTCTTCGTTTGAGGGATTTTCTTCTCCCGGGAGGCGGAAGAGGCGTAGGCGAGGATTCTTGTAGGAATCCTCTCCTCTCCATTGATGCACCGAATGGCTTCTCTTCTTCTCCCCCCGCAGTTTCTTTGCTCCCTGCCTTGTAGTACCAACTCAATCAGGAGCCATTTACATTATAAGCCCCACTTCTTGGGAAACATTATGACTAAGCCTAAAGCTAAAATGAGGCTGCTCAACCGAAACGTAAGTTCCATGGCAAAGAAGAGCTCTCAAGATGTAGCAGAAGGTTCAAGTGATGATGAGAGTGACGGCGAGACATCAAAAACCAAGAAAAGAGCTCCGAGACGTGGAAGAAAGAAAGCCACCATACAAGCATCAGAAGGGGAAACACAAGAAGGTCAAGTGAGCACTGAAGAAGATGAATCCCCTGAAGGGACTAAGAAAATAAAAAGGAGGGGCCGCAAGAAAGCTGCAACTACTGCAAGCTCATCGGAAGAGAAGGACAAAGCAAAAGAACCAAAGAAGAGGGGCAGAAGAAAAGTTAAGACTGTAGAGGAATTGAGTGACAATGAAGGGGAAGATCTGGGTGAAGATCTAGTGCCCTCCAATGACAGGCAGGAGAAAATTTCAGCAAATGACCTAGAAAGTAAAATAGCAGCATTGCTATTAGAAGATACTGATGATAATGATATTAACAATTTAATCCCTCTTGTGTGCTGCTTTGGGCCTGCTAAGTACTCATTTATTCCTTCTGGAAGACCTGCTAATAGGCTGATAGATCATGAAATTCATGAGGGAATGAAAGACATGTTCTGGTCTCCAGATCAATTTGTAAGGGCACCAGGAGGATCATCATCCAATGTTGCTCTTGCTTTAGCAGCTTCTGGTGGCCGGGTTGAATTCATGGGAAAACTAGGCGATGATGATTATGGTCAAAGTACATTATATCACTTGAACGTCAATGGAGTTCAAACTCGGGCAATTAAAATGGACCCTTCAGCGTTTACTGCCATGTCCTTGATGAAGGTCACAGGTAGGGGTAGCTTGAAAATGAGCTGTGCTAAACCTTGTGCAGAGGATTGTTTTGTCCAAACTGATATCAACCCAGCTGTTTTAAAAGAGGCTAAGATGTTTTACTACAATTCTTCAGCTTTGCTTGAGCCCACGACACGATCATCATTGTCGAAAGCAATTGAGGTTTCCAAGAAATTTGGTGGTGTAACATTCTTTGATCTCAATCTTCCACTGCCATTATGGTCGTCCAGTAAGGAGACCAAGTCACTTGTCAAGGAAGCATGGGAAGCTGCTGATATTATTGAAATCACTAAGCAGGAACTTGAGTTCTTGTGTGGCATTAAACCATCTGAGAAATTTGGTACGAAGGATAATGATAAATCCAAATTCACTCACTACAGCCCAGAAGTTGTTACGAAATTGTGGCATGAAAATCTCAAGGTCCTTTTTGTGACAAACGGCACTTCTAAGATTCATTATTACACAAAAGAGCATGATGGCTGGGTTCGTGGCACAGAAGATGCACCAATTACTCCTTTCACCGGTGACATGTCACAATCAGGTGACGCCATTGTTGCAGCTCTGATGAAGATGCTGGCAATTAACCCTCACCTGGTCACTGACAAGGATTACTTGCATACTGCAATGAAACATGCTATTACATGTGGTGTCATTGACCAGTGGTTACTTGCACGAGAACGAGGGTTCCTTCCCAGAGAAAGAGCAGATCCAACCAGTGAACAGTTTGGAGTGAGATTCGTCACAGAGAAGGAATACCGTACACTTCCTGATTCCATACATACAGAGGATTCATCAGAGAGTGAGCTTTTATATGTGGAGTGAACAAAGAAAATGCAGAGGCATGTAATTTTCAATAGAGGGAAAAACCTACAGACATCTGGTGATTTTTCTTGAAGCACCATTTATGGGAACTGCTGCTCTTAACTGGAGTTGGTATTTAGAAGAACTAGTTGTAACCTGCAGGCTCTAGGTTTATTTTTTAACACAGGGTAATAGCCTCAAGATAAACTAACACATCTGTATTGTCAAATTTTGGGTTAAGATTTTGTTGTAAATGTGCATGATTATGGGTGTCAGAAATTTTTCCTAGAACAGATGGATGCTAATTATATATTTCACTGCAACTCCACTATTCTACC
CDS Sequence
- >LOC_Os03g40550.1
ATGCACCGAATGGCTTCTCTTCTTCTCCCCCCGCAGTTTCTTTGCTCCCTGCCTTGTAGTACCAACTCAATCAGGAGCCATTTACATTATAAGCCCCACTTCTTGGGAAACATTATGACTAAGCCTAAAGCTAAAATGAGGCTGCTCAACCGAAACGTAAGTTCCATGGCAAAGAAGAGCTCTCAAGATGTAGCAGAAGGTTCAAGTGATGATGAGAGTGACGGCGAGACATCAAAAACCAAGAAAAGAGCTCCGAGACGTGGAAGAAAGAAAGCCACCATACAAGCATCAGAAGGGGAAACACAAGAAGGTCAAGTGAGCACTGAAGAAGATGAATCCCCTGAAGGGACTAAGAAAATAAAAAGGAGGGGCCGCAAGAAAGCTGCAACTACTGCAAGCTCATCGGAAGAGAAGGACAAAGCAAAAGAACCAAAGAAGAGGGGCAGAAGAAAAGTTAAGACTGTAGAGGAATTGAGTGACAATGAAGGGGAAGATCTGGGTGAAGATCTAGTGCCCTCCAATGACAGGCAGGAGAAAATTTCAGCAAATGACCTAGAAAGTAAAATAGCAGCATTGCTATTAGAAGATACTGATGATAATGATATTAACAATTTAATCCCTCTTGTGTGCTGCTTTGGGCCTGCTAAGTACTCATTTATTCCTTCTGGAAGACCTGCTAATAGGCTGATAGATCATGAAATTCATGAGGGAATGAAAGACATGTTCTGGTCTCCAGATCAATTTGTAAGGGCACCAGGAGGATCATCATCCAATGTTGCTCTTGCTTTAGCAGCTTCTGGTGGCCGGGTTGAATTCATGGGAAAACTAGGCGATGATGATTATGGTCAAAGTACATTATATCACTTGAACGTCAATGGAGTTCAAACTCGGGCAATTAAAATGGACCCTTCAGCGTTTACTGCCATGTCCTTGATGAAGGTCACAGGTAGGGGTAGCTTGAAAATGAGCTGTGCTAAACCTTGTGCAGAGGATTGTTTTGTCCAAACTGATATCAACCCAGCTGTTTTAAAAGAGGCTAAGATGTTTTACTACAATTCTTCAGCTTTGCTTGAGCCCACGACACGATCATCATTGTCGAAAGCAATTGAGGTTTCCAAGAAATTTGGTGGTGTAACATTCTTTGATCTCAATCTTCCACTGCCATTATGGTCGTCCAGTAAGGAGACCAAGTCACTTGTCAAGGAAGCATGGGAAGCTGCTGATATTATTGAAATCACTAAGCAGGAACTTGAGTTCTTGTGTGGCATTAAACCATCTGAGAAATTTGGTACGAAGGATAATGATAAATCCAAATTCACTCACTACAGCCCAGAAGTTGTTACGAAATTGTGGCATGAAAATCTCAAGGTCCTTTTTGTGACAAACGGCACTTCTAAGATTCATTATTACACAAAAGAGCATGATGGCTGGGTTCGTGGCACAGAAGATGCACCAATTACTCCTTTCACCGGTGACATGTCACAATCAGGTGACGCCATTGTTGCAGCTCTGATGAAGATGCTGGCAATTAACCCTCACCTGGTCACTGACAAGGATTACTTGCATACTGCAATGAAACATGCTATTACATGTGGTGTCATTGACCAGTGGTTACTTGCACGAGAACGAGGGTTCCTTCCCAGAGAAAGAGCAGATCCAACCAGTGAACAGTTTGGAGTGAGATTCGTCACAGAGAAGGAATACCGTACACTTCCTGATTCCATACATACAGAGGATTCATCAGAGAGTGAGCTTTTATATGTGGAGTGA
Protein Sequence
- >LOC_Os03g40550.1
MHRMASLLLPPQFLCSLPCSTNSIRSHLHYKPHFLGNIMTKPKAKMRLLNRNVSSMAKKSSQDVAEGSSDDESDGETSKTKKRAPRRGRKKATIQASEGETQEGQVSTEEDESPEGTKKIKRRGRKKAATTASSSEEKDKAKEPKKRGRRKVKTVEELSDNEGEDLGEDLVPSNDRQEKISANDLESKIAALLLEDTDDNDINNLIPLVCCFGPAKYSFIPSGRPANRLIDHEIHEGMKDMFWSPDQFVRAPGGSSSNVALALAASGGRVEFMGKLGDDDYGQSTLYHLNVNGVQTRAIKMDPSAFTAMSLMKVTGRGSLKMSCAKPCAEDCFVQTDINPAVLKEAKMFYYNSSALLEPTTRSSLSKAIEVSKKFGGVTFFDLNLPLPLWSSSKETKSLVKEAWEAADIIEITKQELEFLCGIKPSEKFGTKDNDKSKFTHYSPEVVTKLWHENLKVLFVTNGTSKIHYYTKEHDGWVRGTEDAPITPFTGDMSQSGDAIVAALMKMLAINPHLVTDKDYLHTAMKHAITCGVIDQWLLARERGFLPRERADPTSEQFGVRFVTEKEYRTLPDSIHTEDSSESELLYVE*