Gene Details:

• MSU gene ID: LOC_Os03g24930
• RAPdb gene ID: Os03g0364400
• Gene Symbol: OsBBS1 OsRLCK109 LMM24
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• A guanine insert in OsBBS1 leads to early leaf senescence and salt stress sensitivity in rice (Oryza sativa L.).
• Transgenic LOC_Os03g24930 knockout plants generated by a CRISPR/Cas9 strategy exhibited similar early leaf senescence phenotypes as did the bbs1 mutant, which confirmed that LOC_Os03g24930 was the OsBBS1 gene.
• The OsBBS1 gene was cloned by a map-based cloning strategy, and a guanine (G) insertion was found in the first exon of LOC_Os03g24930.
• The expression of OsBBS1 could be greatly induced by salt stress, and the bbs1 mutant exhibited hypersensitivity to salt stress.
• Chloroplast degradation was observed in LMM24 leaves, with decreased expression of photosynthesis-related genes and increased expression of the senescence-induced STAYGREEN (SGR) gene and other senescence-associated genes.
• The LMM24 mutant displayed dark brown lesions in leaves and growth retardation that were not observed in wild-type ZH8015.
• Furthermore, LMM24 exhibited enhanced resistance to rice blast fungus Magnaporthe oryzae (M.
• LMM24 Encodes Receptor-Like Cytoplasmic Kinase 109, Which Regulates Cell Death and Defense Responses in Rice.
• Our data demonstrate that LMM24 regulates cell death and defense responses in rice.
• The results of histochemical staining and TUNEL assays showed enhanced ROS accumulation and cell death in LMM24.
• The LMM24 gene was identified by MutMap, and LMM24 was confirmed as a receptor-like cytoplasmic kinase 109 by amino acid sequence analysis.
• We identified a new rice lesion mimic mutant LMM24 from a mutant pool of indica rice cultivar "ZhongHui8015".

Function-related keywords:

• leaf ,  leaf-senescence ,  early-leaf-senescence ,  senescence ,  map-based-cloning ,  salt ,  salt-stress ,  stress ,  chloroplast ,  growth ,  resistance ,  defense ,  defense-response ,  blast ,  magnaporthe-oryzae ,  cell-death ,  Kinase ,  lesion ,  lesion-mimic

Literature:

• A guanine insert in OsBBS1 leads to early leaf senescence and salt stress sensitivity in rice (Oryza sativa L.) .  DOI:  10.1007/s00299-018-2280-y ;  PMID:  29572657
• LMM24 Encodes Receptor-Like Cytoplasmic Kinase 109, Which Regulates Cell Death and Defense Responses in Rice .  DOI:  10.3390/ijms20133243 ;  PMID:  31269643

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: