Gene Details:

• MSU gene ID: LOC_Os03g22680
• RAPdb gene ID: Os03g0348900
• Gene Symbol: OsSRFP1 SDEL2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Interestingly, the OsSRFP1-overexpressing plants were less tolerant to salt, cold and oxidative stresses than wild type plants; while the RNA interference silencing of OsSRFP1 plants were more tolerant than wild type without yield penalty.
• Knock-down of stress inducible OsSRFP1 encoding an E3 ubiquitin ligase with transcriptional activation activity confers abiotic stress tolerance through enhancing antioxidant protection in rice.
• Taken together, our results demonstrate that OsSRFP1 may have dual functions in post-translational and transcriptional regulations in modulating abiotic stress responses in rice, at least in part, by negatively regulating antioxidant enzymes-mediated reactive oxygen species removal.
• OsSRFP1 was ubiquitously expressed in various rice organs, with the higher expression levels in roots, panicles and culm nodes.
• The transcript of OsSRFP1 was induced by cold, dehydration, salt, H2O2 and abscisic acid treatments.
• In vitro ubiquitination assays showed that OsSRFP1 possessed E3 ubiquitin ligase activity and the intact RING domain was essential for the activity.
• Consistent with this biochemical function of SDEL1 and SDEL2, enhancing the expression of SDEL1 and SDEL2 results in Pi over-accumulation and induces Pi-starvation signaling even under Pi-sufficient conditions.
• Therefore SDEL1 and SDEL2 facilitate the degradation of SPX4 to modulate PHR2 activity and regulate Pi-homeostasis and Pi-signaling in response to external Pi availability in rice.

Function-related keywords:

• oxidative-stress ,  yield ,  oxidative ,  abiotic-stress ,  culm ,  tolerance ,  stress ,  abscisic-acid ,  stress-tolerance ,  biotic-stress ,  stress-response ,  Ubiquitin ,  reactive-oxygen-species ,  Pi ,  pi

Literature:

• Knock-down of stress inducible OsSRFP1 encoding an E3 ubiquitin ligase with transcriptional activation activity confers abiotic stress tolerance through enhancing antioxidant protection in rice .  DOI:  10.1007/s11103-015-0294-1 ;  PMID:  25667045
• Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice .  DOI:  10.1016/j.molp.2019.04.003 ;  PMID:  31002982
• OsGATA16, a GATA Transcription Factor, Confers Cold Tolerance by Repressing OsWRKY45-1 at the Seedling Stage in Rice .  DOI:  10.1186/s12284-021-00485-w ;  PMID:  33982131

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: