Gene Details:

• MSU gene ID: LOC_Os03g15650
• RAPdb gene ID: Os03g0262900
• Gene Symbol: GLUP6 GEF
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Overall, our results indicate that GLUP6/GEF is the activator of Rab5 GTPase and that the cycling of GTP- and GDP-bound forms of this regulatory protein is essential for the intracellular transport of proglutelin and alpha-globulin from the Golgi to PSVs and in the maintenance of the general structural organization of the endomembrane system in rice seeds.
• Immunofluorescence studies showed that the transport of proglutelins and alpha-globulins to PSV was disrupted in GLUP6 endosperm.
• Secreted granules of glutelin and alpha-globulin were readily observed in young GLUP6 endosperm, followed by the formation of large dilated paramural bodies (PMBs) containing both proteins as the endosperm matures.

Function-related keywords:

• seed ,  endosperm

Literature:

• A guanine nucleotide exchange factor for Rab5 proteins is essential for intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm .  DOI:  10.1104/pp.113.217869 ;  PMID:  23580596

Related News:

Gene Resources:

• NCBI ID: AK070551
• UniProt accessions:

Sequences: