Gene Details:

• MSU gene ID: LOC_Os03g10750
• RAPdb gene ID: Os03g0205000
• Gene Symbol: SPL35
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• SPL35 exhibited decreased chlorophyll content, higher accumulation of H2 O2 , up-regulated expression of defence-related marker genes, and enhanced resistance to both fungal and bacterial pathogens of rice.
• SPL35 directly interacts with the E2 protein OsUBC5a and the coatomer subunit delta proteins Delta-COP1 and Delta-COP2 through the CUE domain, and down-regulation of these interacting proteins also cause development of HR-like lesions resembling those in SPL35 and activation of defence responses, indicating that SPL35 may be involved in the ubiquitination and vesicular trafficking pathways.
• Our findings provide insight into a role of SPL35 in regulating cell death and defence response in plants.
• The SPL35 gene encodes a novel CUE (coupling of ubiquitin conjugation to ER degradation) domain-containing protein that is predominantly localized in cytosol, ER and unknown punctate compartment(s).
• SPL35 is constitutively expressed in all organs, and both overexpression and knockdown of SPL35 cause the lesion mimic phenotype.

Function-related keywords:

• resistance ,  development ,  cell-death ,  Ubiquitin ,  lesion ,  lesion-mimic ,  vesicular ,  vesicular-trafficking ,  defence ,  defence-response

Literature:

• Disruption of gene SPL35, encoding a novel CUE domain-containing protein, leads to cell death and enhanced disease response in rice .  DOI:  10.1111/pbi.13093 ;  PMID:  30771255

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: