Gene Details:

• MSU gene ID: LOC_Os02g57250
• RAPdb gene ID: Os02g0817600
• Gene Symbol: OsIAA10
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Transgenic rice plants overexpressing wild-type or a dominant-negative (degradation-resistant) mutant of OsIAA10 phenocopy RDV symptoms are more susceptible to RDV infection; however, knockdown of OsIAA10 enhances the resistance of rice to RDV infection.
• Rice Dwarf Virus P2 Protein Hijacks Auxin Signaling by Directly Targeting the Rice OsIAA10 Protein, Enhancing Viral Infection and Disease Development.
• In turn, RDV infection triggers increased auxin biosynthesis and accumulation in rice, and that treatment with exogenous auxin reduces OsIAA10 protein level, thereby unleashing a group of OsIAA10-interacting OsARFs to mediate downstream antiviral responses.
• Together with our previous discovery that the viral P2 protein stabilizes OsIAA10 protein via thwarting its interaction with OsTIR1 to enhance viral infection and pathogenesis, our results reveal a novel auxin-IAA10-ARFs-mediated signaling mechanism employed by rice and RDV for defense and counter defense responses.

Function-related keywords:

• resistance ,  auxin ,  disease ,  dwarf ,  disease-development ,  defense ,  defense-response ,  auxin-biosynthesis

Literature:

• Rice Dwarf Virus P2 Protein Hijacks Auxin Signaling by Directly Targeting the Rice OsIAA10 Protein, Enhancing Viral Infection and Disease Development .  DOI:  10.1371/journal.ppat.1005847 ;  PMID:  27606959
• Auxin response factors (ARFs) differentially regulate rice antiviral immune response against rice dwarf virus .  DOI:  10.1371/journal.ppat.1009118 ;  PMID:  33264360

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: