Gene Details:
- MSU gene ID: LOC_Os02g54600
- RAPdb gene ID: Os02g0787300
- Gene Symbol: OsMKK4 LARGE11
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Further results revealed that OsMKK4 influenced brassinosteroid (BR) responses and the expression of BR-related genes.
- Among MAPK kinase (MKKs) gene family, OsMKK4 transcripts were found to be induced in arsenite treated rice leaves and roots.
- Thus, our findings have identified OsMKK4 as a factor for grain size, and suggest a possible link between the MAPK pathways and BRs in grain growth.
- Involvement of the OsMKK4-OsMPK1 Cascade and its Downstream Transcription Factor OsWRKY53 in the Wounding Response in Rice.
- Taken together, components involving in the wounding signaling pathway, OsMKK4-OsMPK1-OsWRKY53, can be important players in regulating crosstalk between abiotic stress and biotic stress.
- Further biochemical and genetic analyses reveal that OsMKKK10, OsMKK4 and OsMAPK6 function in a common pathway to control grain size.
- OsMKK4A227T encoded by the LARGE11-1D allele has stronger kinase activity than OsMKK4.
Function-related keywords:
- brassinosteroid , root , arsenite , grain , grain-size , growth , wounding-response , biotic-stress , Kinase
Literature:
- Arsenic stress activates MAP kinase in rice roots and leaves . DOI: 10.1016/j.abb.2010.11.006 ; PMID: 21081102
- The bHLH Rac Immunity1 (RAI1) Is Activated by OsRac1 via OsMAPK3 and OsMAPK6 in Rice Immunity . DOI: 10.1093/pcp/pcs033 ; PMID: 22437844
- SMALL GRAIN 1, which encodes a mitogen-activated protein kinase kinase 4, influences grain size in rice . DOI: 10.1111/tpj.12405 ; PMID: 24320692
- Involvement of the OsMKK4-OsMPK1 Cascade and its Downstream Transcription Factor OsWRKY53 in the Wounding Response in Rice . DOI: 10.5423/PPJ.OA.10.2013.0106 ; PMID: 25288999
- Control of Grain Size and Weight by the OsMKKK10-OsMKK4-OsMAPK6 Signaling Pathway in Rice . DOI: 10.1016/j.molp.2018.04.004 ; PMID: 29702261
- ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice . DOI: 10.1105/tpc.20.00351 ; PMID: 32616661
- OrMKK3 Influences Morphology and Grain Size in Rice . DOI: 10.1007/s12374-020-09290-2 ; PMID: 33424241
Related News:
Gene Resources:
- NCBI ID: AK120525
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os02g54600.1
CCCTGCCCCCGATCGGCCTCGTCCTCTCCACGCCGCGAGCCCACCAGAAAACGCACACGCCGACGCGAGCCAATCAACCCGCCGCGCCGCGCCTCGCCGCCGTCGCGATGCGACCGGGCGGGCCGCCGAGCTTGCGGGCGGGGCTGCAGCAGCAGCAGCAGCAGCAGCCGGGGACGCCGGGGAGGTCGCGGCGCCGGCCGGATCTCACGCTGCCGCTGCCGCAGCGGGACCTCACGTCGCTCGCGGTGCCGCTGCCGCTGCCGCTGCCGCCGTCGTCGGCGCCGTCGTCGACGTCGTCGTCCGGGTCGTCCTCGCTCGGCGGCGTGCCCACCCCGCCGAATTCGGTCGGCTCCGCGCCGCCGGCCCCGCCGCCGCTGTCGGAGCTGGAGCGCGTCCGCCGCATCGGGAGCGGCGCGGGCGGGACGGTGTGGATGGTGCGGCACCGCCCCACGGGGCGGCCGTACGCGCTCAAGGTGCTCTACGGGAACCACGACGACGCCGTGCGGCGGCAGATCACGCGCGAGATCGCGATCCTCCGCACCGCCGAGCACCCGGCCGTCGTGCGGTGCCACGGCATGTACGAGCAGGCCGGCGAGCTCCAGATCCTGCTCGAGTACATGGACGGGGGATCCCTCGAGGGCCGCCGCATCGCCTCCGAGGCCTTCCTCGCCGACGTCGCGCGCCAGGTGCTCTCCGGGATCGCCTACCTCCACCGCCGCCACATCGTCCACCGCGACATCAAGCCATCCAACCTCCTCATCGACTCCGGCCGCCGCGTCAAGATCGCCGACTTCGGCGTCGGCCGCATCCTCAACCAGACCATGGACCCCTGCAACTCCTCCGTCGGGACCATCGCCTACATGAGCCCCGAGCGCATCAACACCGACCTCAACGACGGCGCCTACGACGGCTACGCCGGCGACATCTGGAGCTTCGGCCTGAGCATTCTCGAGTTCTACATGGGCAGGTTCCCCCTCGGGGAGAATCTCGGCAAGCAGGGAGACTGGGCCGCCCTCATGTGCGCGATTTGCTACTCCGACTCGCCGGCGCCGCCGCCCAACGCCTCGCCGGAGTTCAAGAGCTTCATCAGCTGCTGCCTCCAGAAGAACCCGGCGCGGCGGCCATCGGCGGCGCAGCTTCTCCAACATCGGTTCGTCGCCGGGCCACAGCAGCAGCAGCAGCCGCAGCCGCAGCCCCTCGCACCGCCTCCGTCATGATGAATTCCGATGGGATTCCGGCGTTGATCCGGCTCGGCCATGGATGGACGGTGGTTTGGCATTGAGACGTGGGATCTAGGAGTGCTCTTCCTAGCCATTTTGGGTATTCAAGCCACCACCACAATTTAGTGATTTACCCTCATCATCATCCCCTCTCTTGTCGCTGTTGCTCCTGGAATTAAGCTCCTCTCCTCTCCTCCCCTTCCCCTCCTCAACTTTTCTTTAATCTCTTCTTCTTCTTTTTTTTCTTCTTCTTCTTCCAATTAAGTTCATGTTCTTCCAAATGATCATCATATAATATGGGTTGTTAAGAAAGCAATTTCTTCTTAATTAATTTATTTTCTAAAATCATCATTGGAGCAGTAGAAGTAGTAGTAGTAGTAGGTGGTGGTGTCCATCTGCTCCAGTTGCAGGAGGAGGAGGAGAAGATGGTGACAAAACAACATTGTGATGCTTTGCTGTGCTGGCTTCTTGGATTCTGCAAATTGTGGGGGGTGGATTGGATTGGATTGGATGGATCATGAATGGTTGGAGCAAGCAAATCTTGAAATGGGAACCAAATCAACTTTATTTTTTCCTCCTCCTCTTCCTGAATCCTGATCCTTTCTCTCTGGTGGTTTTGAGGGGAGAATGATCGAATGAAATCATGAATTGCTCTCTTTA
CDS Sequence
- >LOC_Os02g54600.1
ATGCGACCGGGCGGGCCGCCGAGCTTGCGGGCGGGGCTGCAGCAGCAGCAGCAGCAGCAGCCGGGGACGCCGGGGAGGTCGCGGCGCCGGCCGGATCTCACGCTGCCGCTGCCGCAGCGGGACCTCACGTCGCTCGCGGTGCCGCTGCCGCTGCCGCTGCCGCCGTCGTCGGCGCCGTCGTCGACGTCGTCGTCCGGGTCGTCCTCGCTCGGCGGCGTGCCCACCCCGCCGAATTCGGTCGGCTCCGCGCCGCCGGCCCCGCCGCCGCTGTCGGAGCTGGAGCGCGTCCGCCGCATCGGGAGCGGCGCGGGCGGGACGGTGTGGATGGTGCGGCACCGCCCCACGGGGCGGCCGTACGCGCTCAAGGTGCTCTACGGGAACCACGACGACGCCGTGCGGCGGCAGATCACGCGCGAGATCGCGATCCTCCGCACCGCCGAGCACCCGGCCGTCGTGCGGTGCCACGGCATGTACGAGCAGGCCGGCGAGCTCCAGATCCTGCTCGAGTACATGGACGGGGGATCCCTCGAGGGCCGCCGCATCGCCTCCGAGGCCTTCCTCGCCGACGTCGCGCGCCAGGTGCTCTCCGGGATCGCCTACCTCCACCGCCGCCACATCGTCCACCGCGACATCAAGCCATCCAACCTCCTCATCGACTCCGGCCGCCGCGTCAAGATCGCCGACTTCGGCGTCGGCCGCATCCTCAACCAGACCATGGACCCCTGCAACTCCTCCGTCGGGACCATCGCCTACATGAGCCCCGAGCGCATCAACACCGACCTCAACGACGGCGCCTACGACGGCTACGCCGGCGACATCTGGAGCTTCGGCCTGAGCATTCTCGAGTTCTACATGGGCAGGTTCCCCCTCGGGGAGAATCTCGGCAAGCAGGGAGACTGGGCCGCCCTCATGTGCGCGATTTGCTACTCCGACTCGCCGGCGCCGCCGCCCAACGCCTCGCCGGAGTTCAAGAGCTTCATCAGCTGCTGCCTCCAGAAGAACCCGGCGCGGCGGCCATCGGCGGCGCAGCTTCTCCAACATCGGTTCGTCGCCGGGCCACAGCAGCAGCAGCAGCCGCAGCCGCAGCCCCTCGCACCGCCTCCGTCATGA
Protein Sequence
- >LOC_Os02g54600.1
MRPGGPPSLRAGLQQQQQQQPGTPGRSRRRPDLTLPLPQRDLTSLAVPLPLPLPPSSAPSSTSSSGSSSLGGVPTPPNSVGSAPPAPPPLSELERVRRIGSGAGGTVWMVRHRPTGRPYALKVLYGNHDDAVRRQITREIAILRTAEHPAVVRCHGMYEQAGELQILLEYMDGGSLEGRRIASEAFLADVARQVLSGIAYLHRRHIVHRDIKPSNLLIDSGRRVKIADFGVGRILNQTMDPCNSSVGTIAYMSPERINTDLNDGAYDGYAGDIWSFGLSILEFYMGRFPLGENLGKQGDWAALMCAICYSDSPAPPPNASPEFKSFISCCLQKNPARRPSAAQLLQHRFVAGPQQQQQPQPQPLAPPPS*