Information report for OsGpx3;GPX3
Gene Details
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Functional Descriptions
- The mitochondrial glutathione peroxidase GPX3 is essential for H2O2 homeostasis and root and shoot development in rice.
- Transgenic rice plants have been generated that lack mitochondrial OsGpx3.
- These GPX3s plants showed shorter roots and shoots compared to non-transformed (NT) plants, and higher amounts of H2O2 mitochondrial release were observed in the roots of these plants cultivated under normal conditions.
- These results suggest that silencing the mitochondrial OsGpx3 gene impairs normal plant development and leads to a stress-induced morphogenic response via H2O2 accumulation.
- This accumulation of H2O2 is positively associated with shorter root length in GPX3s plants compared to NT ones.
- Moreover, GPX3 promoter analysis indicated that it is mainly expressed in root tissue.
- This study is the first to demonstrate that OsGpx3 plays a role in ABA signaling and corroborate that redox homeostasis enzymes can act in different and complex pathways in plant cells.
- Nipponbare) OsGpx3 is induced after treatment with the phytohormone abscisic acid (ABA) and is involved in its responses and in epigenetic modifications.
Functional Keywords
- homeostasis , mitochondria , root , shoot , ABA , abscisic-acid , phytohormone , redox-homeostasis
Literature and News
- Role of peroxidases in the compensation of cytosolic ascorbate peroxidase knockdown in rice plants under abiotic stress . DOI: 10.1111/j.1365-3040.2011.02366.x ; PMID: 21631533
- Glutathione peroxidase family - an evolutionary overview . DOI: 10.1111/j.1742-4658.2008.06542.x ; PMID: 18616466
- The mitochondrial glutathione peroxidase GPX3 is essential for H2O2 homeostasis and root and shoot development in rice . DOI: 10.1016/j.plantsci.2013.03.017 ; PMID: 23683934
- The mitochondrial isoform glutathione peroxidase 3 (OsGPX3) is involved in ABA responses in rice plants . DOI: 10.1016/j.jprot.2020.104029 ; PMID: 33160103
Gene Resources
- UniProt: B9F1I4
- EMBL: AP005108, AP008208, CM000139
- AlphaFoldDB: B9F1I4
- EnsemblPlants: Os02t0664000-01
- Gramene: Os02t0664000-01
- KEGG: dosa:Os02g0664000, osa:4330235
- Orthologous matrix: KYGNVVI
- InterPro: IPR000889, IPR013766, IPR029759
- PANTHER: PTHR11592, PTHR11592:SF51
- SUPFAM: SSF52833
- PROSITE: PS00460, PS00763, PS51352
- Gene3D: 3.40.30.10
- OrthoDB: B9F1I4
- SWISS-MODEL: B9F1I4
- Conserved Domain Database: cd00340
Sequences
cDNA Sequence
- >LOC_Os02g44500.1
AGATTTTACACACACCGGACTTACCGCTATAAAGCGCGAAGGCCCCCCATCCACGATGCCGTCTCGCACCGCCCCGTTCATCTCTCGCCTCCGGCTCCTCCGAACCGCCGCCGCCCTCTCCCCGTTCTCGTCCTCCGCGCCGCCGCGGCACAGCCCCCGCATCCTCCGCGCTATCCCTGTCGGTGCGCCTCACCCGCCGCGCGTCTCCGCAGCCGTCTCGCCGCTGGTCCGTCCGGTCGCCGCCGGGTTCGCGCTGTTCAGCATGGCCACCGCCGCCTCCTCCGCCGCATCCGTCCACGACTTCACCGTCAAGGATGCAAGTGGCAAAGATGTGGACCTGAGCACCTTCAAGGGGAAAGTCCTCCTTATCGTCAATGTTGCATCTCAGTGTGGCTTGACCAATTCCAACTACACGGAGCTGAGCCAGTTGTATGAGAAGTACAAGGACCAGGGTTTTGAGATCCTTGCTTTCCCATGCAACCAGTTTGGTGGACAGGAACCTGGCACTAATGAGGAGATTGTCCAATTTGCTTGCACCCGCTTCAAGGCCGAGTATCCAATTTTTGATAAGGTTGATGTTAATGGTGACAACACTGCACCCATCTACAAGTTTCTGAAGTCCAGCAAAGGTGGTCTTTTCGGTGACAATATCAAATGGAACTTCTCCAAGTTCTTGGTCGACAAAGAGGGGCGTGTTGTGGAGCGCTATGCGCCAACTACTTCTCCACTCAGCATGGAGAAGGACATCAAGAAGCTGCTTGGAAGTTCTTAAAACCTTACCGCCGGCGCCACCAGATGCACTGCTGCGTTGCATTGAGCACTTGGAACTTCCAATAATGTTGTAATAAAACTGTGCTTGGAATTGCTGTATTTTCATTTGCGTAGCCCTGCTGTGTAATGTATAAAGTATTAACGTGTAATGAAATTGGCTTACTGCATCACTTTGCCCCTTTATTGAAATATTATCTCCTGTATCTGTGTTCGTTATTGAGACCTGCGACTGCGATGAGCAAGTTTTGACGTGTAACGTGTACTCGTTCTATCTGTGC
CDS Sequence
- >LOC_Os02g44500.1
ATGCCGTCTCGCACCGCCCCGTTCATCTCTCGCCTCCGGCTCCTCCGAACCGCCGCCGCCCTCTCCCCGTTCTCGTCCTCCGCGCCGCCGCGGCACAGCCCCCGCATCCTCCGCGCTATCCCTGTCGGTGCGCCTCACCCGCCGCGCGTCTCCGCAGCCGTCTCGCCGCTGGTCCGTCCGGTCGCCGCCGGGTTCGCGCTGTTCAGCATGGCCACCGCCGCCTCCTCCGCCGCATCCGTCCACGACTTCACCGTCAAGGATGCAAGTGGCAAAGATGTGGACCTGAGCACCTTCAAGGGGAAAGTCCTCCTTATCGTCAATGTTGCATCTCAGTGTGGCTTGACCAATTCCAACTACACGGAGCTGAGCCAGTTGTATGAGAAGTACAAGGACCAGGGTTTTGAGATCCTTGCTTTCCCATGCAACCAGTTTGGTGGACAGGAACCTGGCACTAATGAGGAGATTGTCCAATTTGCTTGCACCCGCTTCAAGGCCGAGTATCCAATTTTTGATAAGGTTGATGTTAATGGTGACAACACTGCACCCATCTACAAGTTTCTGAAGTCCAGCAAAGGTGGTCTTTTCGGTGACAATATCAAATGGAACTTCTCCAAGTTCTTGGTCGACAAAGAGGGGCGTGTTGTGGAGCGCTATGCGCCAACTACTTCTCCACTCAGCATGGAGAAGGACATCAAGAAGCTGCTTGGAAGTTCTTAA
Protein Sequence
- >LOC_Os02g44500.1
MPSRTAPFISRLRLLRTAAALSPFSSSAPPRHSPRILRAIPVGAPHPPRVSAAVSPLVRPVAAGFALFSMATAASSAASVHDFTVKDASGKDVDLSTFKGKVLLIVNVASQCGLTNSNYTELSQLYEKYKDQGFEILAFPCNQFGGQEPGTNEEIVQFACTRFKAEYPIFDKVDVNGDNTAPIYKFLKSSKGGLFGDNIKWNFSKFLVDKEGRVVERYAPTTSPLSMEKDIKKLLGSS*