Information report for OsHOX24
Gene Details
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Functional Descriptions
- Characterization of Rice Homeobox Genes, OsHOX22 and OsHOX24, and Over-expression of OsHOX24 in Transgenic Arabidopsis Suggest Their Role in Abiotic Stress Response.
- Over-expression of OsHOX24 imparted higher sensitivity to stress hormone, ABA, and abiotic stresses in the transgenic Arabidopsis plants as revealed by various physiological and phenotypic assays.
- In this study, we carried out functional analysis of two candidate stress-responsive HD-ZIP I class homeobox genes from rice, OsHOX22, and OsHOX24.
- OsHOX24 over-expression rice seedlings showed reduced root and shoot growth under salinity and desiccation stress (DS) conditions.
- In the present study, we raised rice transgenics over-expressing stress-responsive OsHOX24 gene (rice homeodomain-leucine zipper I sub-family member) and analyzed their response to various abiotic stresses at different stages of development.
- At the seed germination stage, rice transgenics over-expressing OsHOX24 exhibited enhanced sensitivity to abiotic stress conditions and abscisic acid as compared to wild-type (WT).
- Over-Expression of OsHOX24 Confers Enhanced Susceptibility to Abiotic Stresses in Transgenic Rice via Modulating Stress-Responsive Gene Expression.
- Taken together, our findings highlighted the role of OsHOX24 in regulation of abiotic stress responses via modulating the expression of stress-responsive genes in rice.
- OsHOX24 mediates regulation of desiccation stress response via complex regulatory network as indicated by its binding to several target genes including transcription factors in rice.
- Gene ontology enrichment analysis revealed that OsHOX24 direct target genes were involved in several biological processes, including plant development, ABA-mediated signalling pathway, ubiquitin-dependent protein catabolic process, ion transport, abiotic and biotic stress responses besides transcriptional and translational regulation.
- In this study, we identified downstream targets of OsHOX24 under control and desiccation stress conditions via chromatin immunoprecipitation-sequencing (ChIP-seq) approach in wild-type and OsHOX24 over-expression transgenic in rice.
Functional Keywords
- abiotic-stress , stress , biotic-stress , stress-response , homeobox-gene , seedlings , root , growth , shoot , development , seed , salinity , seed-germination , abscisic-acid , transcription-factor , plant-development
Literature and News
- Characterization of Rice Homeobox Genes, OsHOX22 and OsHOX24, and Over-expression of OsHOX24 in Transgenic Arabidopsis Suggest Their Role in Abiotic Stress Response . DOI: 10.3389/fpls.2016.00627 ; PMID: 27242831
- Over-Expression of OsHOX24 Confers Enhanced Susceptibility to Abiotic Stresses in Transgenic Rice via Modulating Stress-Responsive Gene Expression . DOI: 10.3389/fpls.2017.00628 ; PMID: 28484484
- Genome-wide discovery of OsHOX24-binding sites and regulation of desiccation stress response in rice . DOI: 10.1007/s11103-020-01078-9 ; PMID: 33025523
- A comprehensive transcriptome analysis of contrasting rice cultivars highlights the role of auxin and ABA responsive genes in heat stress response . DOI: 10.1016/j.ygeno.2021.03.007 ; PMID: 33705886
Gene Resources
- UniProt: B7E8X8
- EMBL: AK063685, EU847515
- AlphaFoldDB: B7E8X8
- EnsemblPlants: Os02t0649300-01
- Gramene: Os02t0649300-01
- KEGG: dosa:Os02g0649300
- Orthologous matrix: CATPDLW
- InterPro: IPR000047, IPR001356, IPR003106
- PANTHER: PTHR24326, PTHR24326:SF341
- SUPFAM: SSF46689
- PROSITE: PS00027, PS50071
- Gene3D: 1.10.10.60
- OrthoDB: B7E8X8
- SWISS-MODEL: B7E8X8
- Conserved Domain Database: cd00086
Sequences
cDNA Sequence
- >LOC_Os02g43330.1
TGGAACACACACACTACTGCGACTGCTAGTGCTCTGGTCTTACATTCGACGAACTGATCGATATTCGATACGACGTCTCCTCCTACCTGGAGCTTGGGAAAAATGGAGAGCGACTGCCAGTTCTTGGTGGCGCCGCCGCAGCCGCACATGTACTACGACACGGCGGCGGCGGCGGTGGACGAGGCGCAGTTCTTGCGGCAGATGGTGGCCGCGGCGGATCACCACGCGGCCGCCGCTGGGAGAGGAGGCGGCGACGGCGACGGCGGCGGCGGCGGCGGCGGTGGCGGGGAGAGGAAGCGGCGGTTCACGGAGGAGCAGGTGCGGTCGCTGGAGACGACGTTCCACGCGCGGCGGGCCAAGCTGGAGCCGCGGGAGAAGGCGGAGCTGGCGCGGGAGCTCGGGCTGCAGCCGCGCCAGGTGGCCATCTGGTTCCAGAACAAGCGCGCCCGGTGGCGCTCCAAGCAGATCGAGCACGACTACGCCGCGCTCCGCGCCCAGTACGACGCCCTCCACGCCCGCGTCGAGTCGCTCAGGCAGGAGAAGCTCGCCCTCGCAGACCAGGTGGATGAGCTGAGGGGGAAGCTGAACGAGCGGCAAGACCAGAGCGGCAGCTGCGACGGCGGCGGCGCCGAAGGGGACGACGACGACAAGAGGAATAGCGTGATGAACGCGAGCAGCAGCGGCCTCGTGGAGGAGGACTACGTGAGCTGCCTCGCGGTGCCGGTGGTGGACGTCTCGGAGGACGGCTCGGCGGCGTGCGGCGGGTCGTCGTACGAGTACGACCATCACCTAGACTACTTGGGCGGCGGCCAGCTGCCCGATCCGTTCTGCGGCATGCCGGATCTGTGGGAGATATGGCCAATGGTGGAATGGAACGCAGTAGCATGATCATGCTAATCAATCAGCGTAGCATACAGTATATAAATATATATGTGTATGAGTACGTGTTGTATTGGGTCTATATAGATATTTTGCTGCTGTTGCTGCTGCTGGCTTGTGCAGTCAGTTGGTCCGGAGAGATCGACTAGAGCCGCGGCGCTCGTAAGCTAGACGGGAGAGCAGATTAGAGATGGAGGATGCAACCGGCCGGCCGGCAAACCATGCAACAATGCAAATCCACACATGCATTGCGTTGCACAGATAGAAATCCTCCGGCCGGTCGATCGCCGAGTCTTGCTGCTTGTTATGCTAGGATGCTACATTAATTATTCATGTTCGTGAATCTGGCTCCCCTGCCTCGGAGCCCGTTCGTGCACATATGTGAAACATATATATCAACGCTGCGCATGTGTGCCATGCCCATGCGCATGCCGGCGCTTGTCGTCCATGCTTTGAA
CDS Sequence
- >LOC_Os02g43330.1
ATGGAGAGCGACTGCCAGTTCTTGGTGGCGCCGCCGCAGCCGCACATGTACTACGACACGGCGGCGGCGGCGGTGGACGAGGCGCAGTTCTTGCGGCAGATGGTGGCCGCGGCGGATCACCACGCGGCCGCCGCTGGGAGAGGAGGCGGCGACGGCGACGGCGGCGGCGGCGGCGGCGGTGGCGGGGAGAGGAAGCGGCGGTTCACGGAGGAGCAGGTGCGGTCGCTGGAGACGACGTTCCACGCGCGGCGGGCCAAGCTGGAGCCGCGGGAGAAGGCGGAGCTGGCGCGGGAGCTCGGGCTGCAGCCGCGCCAGGTGGCCATCTGGTTCCAGAACAAGCGCGCCCGGTGGCGCTCCAAGCAGATCGAGCACGACTACGCCGCGCTCCGCGCCCAGTACGACGCCCTCCACGCCCGCGTCGAGTCGCTCAGGCAGGAGAAGCTCGCCCTCGCAGACCAGGTGGATGAGCTGAGGGGGAAGCTGAACGAGCGGCAAGACCAGAGCGGCAGCTGCGACGGCGGCGGCGCCGAAGGGGACGACGACGACAAGAGGAATAGCGTGATGAACGCGAGCAGCAGCGGCCTCGTGGAGGAGGACTACGTGAGCTGCCTCGCGGTGCCGGTGGTGGACGTCTCGGAGGACGGCTCGGCGGCGTGCGGCGGGTCGTCGTACGAGTACGACCATCACCTAGACTACTTGGGCGGCGGCCAGCTGCCCGATCCGTTCTGCGGCATGCCGGATCTGTGGGAGATATGGCCAATGGTGGAATGGAACGCAGTAGCATGA
Protein Sequence
- >LOC_Os02g43330.1
MESDCQFLVAPPQPHMYYDTAAAAVDEAQFLRQMVAAADHHAAAAGRGGGDGDGGGGGGGGGERKRRFTEEQVRSLETTFHARRAKLEPREKAELARELGLQPRQVAIWFQNKRARWRSKQIEHDYAALRAQYDALHARVESLRQEKLALADQVDELRGKLNERQDQSGSCDGGGAEGDDDDKRNSVMNASSSGLVEEDYVSCLAVPVVDVSEDGSAACGGSSYEYDHHLDYLGGGQLPDPFCGMPDLWEIWPMVEWNAVA*