Gene Details:

Functional Descriptions:

  • Our results suggest that OsSHOC1 and OsPTD1 are essential for rice fertilization and CO formation, possibly by stabilizing the recombinant intermediates during meiosis.
  • OsSHOC1 was sterile both in male and female gametophytes, and it showed a striking reduction in the number of meiotic COs, indicating that OsSHOC1 was required for normal CO formation.
  • Further investigations showed that OsSHOC1 physically interacted with OsPTD1 and that the latter was also required for normal CO formation and plant fertility.
  • OsSHOC1 and OsPTD1 are essential for crossover formation during rice meiosis.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >LOC_Os02g42910.1
    AGTAGAACACACAAGGCAATGCAGCGGAAACCCACCGCAACTCCGCATTCCGCAAGCCAAGATCAAAAGTTGGCGTATCAAAACATTTTGAAAACCAAAAAATTCGTCTTCAACCTCCTGCTCCCCTCGCTTCGTTCTCCGCCGCGCCATTCGCCATGAGGACCCGCTTCCTCGCCACCGACTACTTCGCGCCGTCCTCCTCCTCCGCCGCCGGCAAAGCGCTAGCCCTAGAGTTCTTCAGCTTCCCCTCTCTCCCCGTCCCCGCCCTTCCTCCCGATCCCCACTTCCTCCCGTTCACCTCCGCCGACGAACTCCCAGCCGCCACGGTCGCCGACGATGGTCTCGGCCCTCTCCCCATCGCCTCCGCGCTCTCCGATTTCCTCGCCGCGGTTATCCCGCAGGCCCTGCCTGTGCCGACTGTGCCCGCGGCCGACGAGGTATTGGACGACTTCCTGTACGACAGAGGCGGATACGGCGAGGATTTCAGCTCATGGGAGTTTGGTGCATTCAGAATCCCTAAGGGGTATGGCGTGATCAACCGCGAGAAGGATGAAAAGGGGGAGGGCTCTAGATCAGACGGTCTGGAGATCTCCTCAGTTATGAAGAGGTGGGAACAATTGAAGGAGCTTAGATTTGAGGTTGTAGAGGTGGATCTCCTAATGGCTTTGCAAGAAGACATTGCATCCTTTGGTGAAGAGGAGTCTGGTGGTGGTGTCACGTTGTTGCTTCGTGTTCCAGATATGAAAATCCATTTGGATTTCATTGATATTGAGACCGACATAAAAATAAGATATCAATCTGATCTTCCAGAGTCAGTGTATCAAGTAGAAAAGGTCCCTGTAAAAGACAATGATGGCAATGGCCATTCTTCTCTGAGAGAAGACTGCTGCTTGGAGATTGCAGCACTAGATCATGGTGCAGTAATACCTCGATTGGAAGTAAGTAGGAATTCTTGGGAGCTCGACGATTGTCTGACTGAGACTGACAGATACGGTGTTTTTGATAATGTTGTTAGACACTTGGATGAAGCACAGATTCAGCATTCAGTGTTTAAATCAACCGAGTTCTTGAGATCAACTGACATGGACATGCTGACCTTTGTTTGTGAAGATGCACCATGCCATGACATTCAAGTAGATAAACCAGCAGAAATCAAAGCTGCAGTAGAAATGGATGTTGTGAGGATCAATGGCAATATTCTGCTTGAGAAAAATTCAGCACTCTACCCTCTCAAGCCTGATGGCACCTGTTCAGACTTGCCTTGCTCCATTCTTTTAGAGGAGGTACAGATCATTGATTTTCCTTCAGATAATGTATTCAAAATGCTTGTTCAGTCAGAGACAAATAAGATGAATATATCTGATGAAATATTCAAAGATGATTTTGATCCAGCAAGACGTTTGTATGAATCAATGGTTAGCTGCGAGTTAGCACTGGTTGATGATACATTTAGGTCATTGCCTACACCTATTTTAAATGATGATATAGCAGTTAGGTCTAGGGTCCCTCCCATTCAAGAAATACTATGCTCCCTAAAACCACACCCTCTATCAGCATCTGATGGAATTTATTTGGATTGGCATCTCTTACTGGAAGGACCATGCAACCGGGAGATTTGTTGTTCTTATGCAAGCATGGTTGAGGAGGCAAAAACTTGCCATTTAAGTTCTGAGCTGCAAAGGAGTTGTCAGAGTACATCAGTATTTGTTAGCGATTTTCTGGAGGATTTTCAGAGAAGTCCAAAGCTTCAAGATGAGGATAAACATAGCGATATTTATGTTCCTGCCCCACTGTCTCATGATCCACAAAAATTGGAAGCAACTCAAAAATGCGAACAAGAAGGTGGTACTAGAAACCATAGTTCCATGAAAAGACCGAGTCCAGAAAAGTCATCTTCCTTCCCTGAGTTAATATCACATTCTGGTGACCTAAATTTTTACTTAAACGTCAGAAGTGCCACTAAGAGTGGAACCAATAATGAGAATACTTCTACTTTAGATGTCCCGCATTCAGAAGAGCAAGCATTATCTCTTTCAACCAGGGCTAAGGTTGACAAACTCATAGAAATTCATCCTGTCAGCCCCTCAAATCTTATTCAAGGCCTTATAGAACAAATCCATGCAAGCTATACATCTGCTCTGCAAGAAAGCACATATTGGAGGCATTCTTTCTCAGATGAGCAAGGTTTAGGAATCTCAAAGCAGAAACTTCTTGAACTGATAACGGGAGAAGGTTCAGAAGGCTCGTACAATCACTGCGAACACAAAGATAAGATGGAACTCATTGTACTGTATGCATTAAAGCAGGTTGCATATTACTTATGTTTCTTTGGTCTGCATGCGGCCCATTTGTACATTAGCAACCTGACTAGAAGCTTGGAAAACACTCCTGAGAGGTTAAAACATATTCTATGGTCCATTTCTGAAGCACAGAGGAAATCTGAGAGGCAACTGTTTGAATCTCATCCGTCATTGTCATGCATTGAGACTATCCTGAGATCTAATAAACAAATCGACCAAAAGATCCTTATAGTTGCTGATAGAGCTTTCTGGCTGCCACTGGGTCAAAAGCTAGCATCCATGAGGATGACATTTGTTGAGTTTGGACAAAACCCTGCAACAACTTTTGTGGATCTGGTGAACAAGACAAACTCTACAGCTTGGGTGCTGGAAGAATTACTGAAATCAGATTGCATTCTGCTAGATAACAAGAACATTCCAGCTTCATTCCCTTTTGACAAGTTTGGCATCATACTGGAATATGGAGGCCCGAATAAATCATCTACCTTGTTATCTCTCGCTCCTAAATTAGATGGTTTGCCACCTCTGCATTTCCTCTATGTCAAAGTTGATGGCAAGGACTTTCCAGCTGCTCTAGTCGAGGACAACCATAAAGACCAGGATTTGAAATCTACATTGGATAAAGTTTTGCTTACACTTCAGAAGGATTTGCAGGAGAGGATGAATAAAATGCGTATTGTTGATTCGTTAAACTTCATACCAGCAACAAATCAACTGCAAGGTCTTCAAGAAAAACGGAGCAAACATTTTGCTGCTGATGCTACAAAAGAACTGCTTCCAGATGATCAACCACACAGATTACAAAATCTTAACAAGAAGAATACTTTTGATTCACATAACGTTGTGCTTGCTGATGAACAGCTACATATACAGCAAACACTGAGTAATAAACCTGTTGTCAATTCACAATGTGTACCCACAGTTGAGAAGAGTAGCTCTACTTCTTCTGTATCTGCCAATGTGCTGAAAGACCCTCAAGAGAATCAGTCCACTACTGACTTACCTTCCTGTGTGAAAAATGACTGCATCATGCCAGGAAGACTGTCCGTCCCAGATGTAGTGATAGTTGTAAATACTGGAAATCATGGAAAGACGATGCTTGTTTCGCGAAGATCATCTTATCAGCAGATACTAGCTCTGGAGAAAGGAGGAATGCAGGTCGTGGAGCGAGATATTGATCTGCCTGTGGATCTGATACTCAGTGCTGCTGTCTGCCTAGTATGGTATGAGACTGCGCTCTTTGAGGCCAATGAACTAACAACATCAGCAGAGACATCTGGTATAAAAGAAAATGTAGAGAATATTGCGACCAACATTCTGATGTCAGTTAGTTTCTCTTTCACTGGCTGCATCATGGTCTTTGAGGGAGAAGCTGACTTCCTTTCTGCTGTAATGGACTCATCTGATTCATTGTATACTGCAGCTGCTAGTTTGGACATGAACTTGCAGCTGTTCTTCTCACACACACCCAGGTCAACAGATGAAATAATTCTCAATTGCATTACAAATGTGACTAGCTGTTATAAAGCTCCTCTTCCAGATATACCTGAATCAGAAAGCCTGGCTGAATCATTTCTCACAAGTTTCCCTTCCATCAATCCCGTGTCTGCATATATGTTACTTTCTTCTGGAGGCAGCCTTGTGGAGTTCCTCAGTTGGCCACATGAGCGCCGTATTCAAGCAGTTGGAAAGTATCTTTTGTCTCCAAAGATCATTTCCCTATTTAATGCTTTGTGCAAATTTGGTGAGTTAGGTGAATCAAGGTCTGTAATGACTGAATGCTCTTCAGTCGATTCAGATATCAGTAGTGCATTCCTGCAGTCTCCGAGGAAAAGGAAACAGCGTTCATTGCAGGCTTGTGCAGTACCAACTAATAAGCTCCTCTTTTCTGATTCTCTAAACCAAATACCTGGTGACTATGCAGAACATGCTGAGGTATTCTCACCTTCTAAGTTGAGGAAGTTCTCTGACATGGATAATACAATTCCCGAGCTCCCAGATGTCTTTACATTCGACGAAAGTTTGAATATGAGAAGTGAGGGATTCTCTTATCAACAAAAGAAGCATGATGTGGATGCAATACCTGGTAATCAAGTCATTAATGATGATTTCAGCAATGGATTGACACCAAATAATCAAGCATATAACAGAAGGACTGGCAATATGGTGGACACATTCGACTTACCCTGGCAACCTGAATTTGGTGGTACGCATCCAAGCAAAAGCACTTTTCACACAAGCAGACCATCTTGCAGCAGAACTCATAGCAATCCAGTATTTTCAACTGCATTTGAGATCAACGATGATCCTGGTGAGTGGAACATTTCAGGAGGTACAAAACAAACATGGAAGGGGCTTGCACATGGAGGTACTGTAGACGACTCTTACAGATATGATATGGACAACAGATATCATGAACCAAGAGATGAAATTATGCAACATCCAGCAAGTTCGCTTGCTTTTCAGAAACTAGATTTTGGTAGCCATGCAACTTCACAGGGGTCATGCTGGGAAATTGATTATCTAAGGCAAATGAGTGCAAAGAGAAAAGCACGTCAGGAGAGATCTAGATGTAGTAATTCACCAGGTATGTCGATCCCAAGAATGAGAGATAGCAACTCAAAGATTCTAAATCCTCCACCTAAAGAATCCTTCAGATACCGAGGAGATAGAGACACTCCTTCGAGGGACCAGAGCCCTTCAATTGGGACTCAGCATTATGGGAAAGGCAAGGAAGGAGCTAAAGCACAGAATCGCAGAGCAAGGAAAGATTTCAATGTACAACCAACAAGTCACAAAAAGAGGATAGAACCGTCCATTGATCCAACATGGACTCCTATTGACAAGAGAGCAAGACAGAAACTTTCATTTGTTACATATGGGAAGGAAAAACAGAGCAAGCTGGTCTGGCGAAACCAGAACAGCCCTGGTGTTGGGTGTGGCTTCCGGAAAAGATTCCGAGAGGAAGGTACGTAGATTATCATGTCAGGTCAGATAAGCTCCCTGTGCCCTATCCTCAAATAGATTTCGAGAGGAAAGTACGTAGATTTTCATGTCAGGTCAGATAAGCTCCCTGTCCCTGTATCCTCAAATTTAAGTTGCTGGTGTTTTATTTTGTAAAGATATTCCATGAAGATATGTCTAAACTCTTAACTTACGTAAAGAAGTGATTTACACCTAAAAGCCGCTCATGCATTCAAAAGCACTGGCGGTATAGGTTAAATGGTATATTGAATAGGCTAACTTTTCGAGACCA
CDS Sequence
  • >LOC_Os02g42910.1
    ATGAGGACCCGCTTCCTCGCCACCGACTACTTCGCGCCGTCCTCCTCCTCCGCCGCCGGCAAAGCGCTAGCCCTAGAGTTCTTCAGCTTCCCCTCTCTCCCCGTCCCCGCCCTTCCTCCCGATCCCCACTTCCTCCCGTTCACCTCCGCCGACGAACTCCCAGCCGCCACGGTCGCCGACGATGGTCTCGGCCCTCTCCCCATCGCCTCCGCGCTCTCCGATTTCCTCGCCGCGGTTATCCCGCAGGCCCTGCCTGTGCCGACTGTGCCCGCGGCCGACGAGGTATTGGACGACTTCCTGTACGACAGAGGCGGATACGGCGAGGATTTCAGCTCATGGGAGTTTGGTGCATTCAGAATCCCTAAGGGGTATGGCGTGATCAACCGCGAGAAGGATGAAAAGGGGGAGGGCTCTAGATCAGACGGTCTGGAGATCTCCTCAGTTATGAAGAGGTGGGAACAATTGAAGGAGCTTAGATTTGAGGTTGTAGAGGTGGATCTCCTAATGGCTTTGCAAGAAGACATTGCATCCTTTGGTGAAGAGGAGTCTGGTGGTGGTGTCACGTTGTTGCTTCGTGTTCCAGATATGAAAATCCATTTGGATTTCATTGATATTGAGACCGACATAAAAATAAGATATCAATCTGATCTTCCAGAGTCAGTGTATCAAGTAGAAAAGGTCCCTGTAAAAGACAATGATGGCAATGGCCATTCTTCTCTGAGAGAAGACTGCTGCTTGGAGATTGCAGCACTAGATCATGGTGCAGTAATACCTCGATTGGAAGTAAGTAGGAATTCTTGGGAGCTCGACGATTGTCTGACTGAGACTGACAGATACGGTGTTTTTGATAATGTTGTTAGACACTTGGATGAAGCACAGATTCAGCATTCAGTGTTTAAATCAACCGAGTTCTTGAGATCAACTGACATGGACATGCTGACCTTTGTTTGTGAAGATGCACCATGCCATGACATTCAAGTAGATAAACCAGCAGAAATCAAAGCTGCAGTAGAAATGGATGTTGTGAGGATCAATGGCAATATTCTGCTTGAGAAAAATTCAGCACTCTACCCTCTCAAGCCTGATGGCACCTGTTCAGACTTGCCTTGCTCCATTCTTTTAGAGGAGGTACAGATCATTGATTTTCCTTCAGATAATGTATTCAAAATGCTTGTTCAGTCAGAGACAAATAAGATGAATATATCTGATGAAATATTCAAAGATGATTTTGATCCAGCAAGACGTTTGTATGAATCAATGGTTAGCTGCGAGTTAGCACTGGTTGATGATACATTTAGGTCATTGCCTACACCTATTTTAAATGATGATATAGCAGTTAGGTCTAGGGTCCCTCCCATTCAAGAAATACTATGCTCCCTAAAACCACACCCTCTATCAGCATCTGATGGAATTTATTTGGATTGGCATCTCTTACTGGAAGGACCATGCAACCGGGAGATTTGTTGTTCTTATGCAAGCATGGTTGAGGAGGCAAAAACTTGCCATTTAAGTTCTGAGCTGCAAAGGAGTTGTCAGAGTACATCAGTATTTGTTAGCGATTTTCTGGAGGATTTTCAGAGAAGTCCAAAGCTTCAAGATGAGGATAAACATAGCGATATTTATGTTCCTGCCCCACTGTCTCATGATCCACAAAAATTGGAAGCAACTCAAAAATGCGAACAAGAAGGTGGTACTAGAAACCATAGTTCCATGAAAAGACCGAGTCCAGAAAAGTCATCTTCCTTCCCTGAGTTAATATCACATTCTGGTGACCTAAATTTTTACTTAAACGTCAGAAGTGCCACTAAGAGTGGAACCAATAATGAGAATACTTCTACTTTAGATGTCCCGCATTCAGAAGAGCAAGCATTATCTCTTTCAACCAGGGCTAAGGTTGACAAACTCATAGAAATTCATCCTGTCAGCCCCTCAAATCTTATTCAAGGCCTTATAGAACAAATCCATGCAAGCTATACATCTGCTCTGCAAGAAAGCACATATTGGAGGCATTCTTTCTCAGATGAGCAAGGTTTAGGAATCTCAAAGCAGAAACTTCTTGAACTGATAACGGGAGAAGGTTCAGAAGGCTCGTACAATCACTGCGAACACAAAGATAAGATGGAACTCATTGTACTGTATGCATTAAAGCAGGTTGCATATTACTTATGTTTCTTTGGTCTGCATGCGGCCCATTTGTACATTAGCAACCTGACTAGAAGCTTGGAAAACACTCCTGAGAGGTTAAAACATATTCTATGGTCCATTTCTGAAGCACAGAGGAAATCTGAGAGGCAACTGTTTGAATCTCATCCGTCATTGTCATGCATTGAGACTATCCTGAGATCTAATAAACAAATCGACCAAAAGATCCTTATAGTTGCTGATAGAGCTTTCTGGCTGCCACTGGGTCAAAAGCTAGCATCCATGAGGATGACATTTGTTGAGTTTGGACAAAACCCTGCAACAACTTTTGTGGATCTGGTGAACAAGACAAACTCTACAGCTTGGGTGCTGGAAGAATTACTGAAATCAGATTGCATTCTGCTAGATAACAAGAACATTCCAGCTTCATTCCCTTTTGACAAGTTTGGCATCATACTGGAATATGGAGGCCCGAATAAATCATCTACCTTGTTATCTCTCGCTCCTAAATTAGATGGTTTGCCACCTCTGCATTTCCTCTATGTCAAAGTTGATGGCAAGGACTTTCCAGCTGCTCTAGTCGAGGACAACCATAAAGACCAGGATTTGAAATCTACATTGGATAAAGTTTTGCTTACACTTCAGAAGGATTTGCAGGAGAGGATGAATAAAATGCGTATTGTTGATTCGTTAAACTTCATACCAGCAACAAATCAACTGCAAGGTCTTCAAGAAAAACGGAGCAAACATTTTGCTGCTGATGCTACAAAAGAACTGCTTCCAGATGATCAACCACACAGATTACAAAATCTTAACAAGAAGAATACTTTTGATTCACATAACGTTGTGCTTGCTGATGAACAGCTACATATACAGCAAACACTGAGTAATAAACCTGTTGTCAATTCACAATGTGTACCCACAGTTGAGAAGAGTAGCTCTACTTCTTCTGTATCTGCCAATGTGCTGAAAGACCCTCAAGAGAATCAGTCCACTACTGACTTACCTTCCTGTGTGAAAAATGACTGCATCATGCCAGGAAGACTGTCCGTCCCAGATGTAGTGATAGTTGTAAATACTGGAAATCATGGAAAGACGATGCTTGTTTCGCGAAGATCATCTTATCAGCAGATACTAGCTCTGGAGAAAGGAGGAATGCAGGTCGTGGAGCGAGATATTGATCTGCCTGTGGATCTGATACTCAGTGCTGCTGTCTGCCTAGTATGGTATGAGACTGCGCTCTTTGAGGCCAATGAACTAACAACATCAGCAGAGACATCTGGTATAAAAGAAAATGTAGAGAATATTGCGACCAACATTCTGATGTCAGTTAGTTTCTCTTTCACTGGCTGCATCATGGTCTTTGAGGGAGAAGCTGACTTCCTTTCTGCTGTAATGGACTCATCTGATTCATTGTATACTGCAGCTGCTAGTTTGGACATGAACTTGCAGCTGTTCTTCTCACACACACCCAGGTCAACAGATGAAATAATTCTCAATTGCATTACAAATGTGACTAGCTGTTATAAAGCTCCTCTTCCAGATATACCTGAATCAGAAAGCCTGGCTGAATCATTTCTCACAAGTTTCCCTTCCATCAATCCCGTGTCTGCATATATGTTACTTTCTTCTGGAGGCAGCCTTGTGGAGTTCCTCAGTTGGCCACATGAGCGCCGTATTCAAGCAGTTGGAAAGTATCTTTTGTCTCCAAAGATCATTTCCCTATTTAATGCTTTGTGCAAATTTGGTGAGTTAGGTGAATCAAGGTCTGTAATGACTGAATGCTCTTCAGTCGATTCAGATATCAGTAGTGCATTCCTGCAGTCTCCGAGGAAAAGGAAACAGCGTTCATTGCAGGCTTGTGCAGTACCAACTAATAAGCTCCTCTTTTCTGATTCTCTAAACCAAATACCTGGTGACTATGCAGAACATGCTGAGGTATTCTCACCTTCTAAGTTGAGGAAGTTCTCTGACATGGATAATACAATTCCCGAGCTCCCAGATGTCTTTACATTCGACGAAAGTTTGAATATGAGAAGTGAGGGATTCTCTTATCAACAAAAGAAGCATGATGTGGATGCAATACCTGGTAATCAAGTCATTAATGATGATTTCAGCAATGGATTGACACCAAATAATCAAGCATATAACAGAAGGACTGGCAATATGGTGGACACATTCGACTTACCCTGGCAACCTGAATTTGGTGGTACGCATCCAAGCAAAAGCACTTTTCACACAAGCAGACCATCTTGCAGCAGAACTCATAGCAATCCAGTATTTTCAACTGCATTTGAGATCAACGATGATCCTGGTGAGTGGAACATTTCAGGAGGTACAAAACAAACATGGAAGGGGCTTGCACATGGAGGTACTGTAGACGACTCTTACAGATATGATATGGACAACAGATATCATGAACCAAGAGATGAAATTATGCAACATCCAGCAAGTTCGCTTGCTTTTCAGAAACTAGATTTTGGTAGCCATGCAACTTCACAGGGGTCATGCTGGGAAATTGATTATCTAAGGCAAATGAGTGCAAAGAGAAAAGCACGTCAGGAGAGATCTAGATGTAGTAATTCACCAGGTATGTCGATCCCAAGAATGAGAGATAGCAACTCAAAGATTCTAAATCCTCCACCTAAAGAATCCTTCAGATACCGAGGAGATAGAGACACTCCTTCGAGGGACCAGAGCCCTTCAATTGGGACTCAGCATTATGGGAAAGGCAAGGAAGGAGCTAAAGCACAGAATCGCAGAGCAAGGAAAGATTTCAATGTACAACCAACAAGTCACAAAAAGAGGATAGAACCGTCCATTGATCCAACATGGACTCCTATTGACAAGAGAGCAAGACAGAAACTTTCATTTGTTACATATGGGAAGGAAAAACAGAGCAAGCTGGTCTGGCGAAACCAGAACAGCCCTGGTGTTGGGTGTGGCTTCCGGAAAAGATTCCGAGAGGAAGGTACGTAG
Protein Sequence
  • >LOC_Os02g42910.1
    MRTRFLATDYFAPSSSSAAGKALALEFFSFPSLPVPALPPDPHFLPFTSADELPAATVADDGLGPLPIASALSDFLAAVIPQALPVPTVPAADEVLDDFLYDRGGYGEDFSSWEFGAFRIPKGYGVINREKDEKGEGSRSDGLEISSVMKRWEQLKELRFEVVEVDLLMALQEDIASFGEEESGGGVTLLLRVPDMKIHLDFIDIETDIKIRYQSDLPESVYQVEKVPVKDNDGNGHSSLREDCCLEIAALDHGAVIPRLEVSRNSWELDDCLTETDRYGVFDNVVRHLDEAQIQHSVFKSTEFLRSTDMDMLTFVCEDAPCHDIQVDKPAEIKAAVEMDVVRINGNILLEKNSALYPLKPDGTCSDLPCSILLEEVQIIDFPSDNVFKMLVQSETNKMNISDEIFKDDFDPARRLYESMVSCELALVDDTFRSLPTPILNDDIAVRSRVPPIQEILCSLKPHPLSASDGIYLDWHLLLEGPCNREICCSYASMVEEAKTCHLSSELQRSCQSTSVFVSDFLEDFQRSPKLQDEDKHSDIYVPAPLSHDPQKLEATQKCEQEGGTRNHSSMKRPSPEKSSSFPELISHSGDLNFYLNVRSATKSGTNNENTSTLDVPHSEEQALSLSTRAKVDKLIEIHPVSPSNLIQGLIEQIHASYTSALQESTYWRHSFSDEQGLGISKQKLLELITGEGSEGSYNHCEHKDKMELIVLYALKQVAYYLCFFGLHAAHLYISNLTRSLENTPERLKHILWSISEAQRKSERQLFESHPSLSCIETILRSNKQIDQKILIVADRAFWLPLGQKLASMRMTFVEFGQNPATTFVDLVNKTNSTAWVLEELLKSDCILLDNKNIPASFPFDKFGIILEYGGPNKSSTLLSLAPKLDGLPPLHFLYVKVDGKDFPAALVEDNHKDQDLKSTLDKVLLTLQKDLQERMNKMRIVDSLNFIPATNQLQGLQEKRSKHFAADATKELLPDDQPHRLQNLNKKNTFDSHNVVLADEQLHIQQTLSNKPVVNSQCVPTVEKSSSTSSVSANVLKDPQENQSTTDLPSCVKNDCIMPGRLSVPDVVIVVNTGNHGKTMLVSRRSSYQQILALEKGGMQVVERDIDLPVDLILSAAVCLVWYETALFEANELTTSAETSGIKENVENIATNILMSVSFSFTGCIMVFEGEADFLSAVMDSSDSLYTAAASLDMNLQLFFSHTPRSTDEIILNCITNVTSCYKAPLPDIPESESLAESFLTSFPSINPVSAYMLLSSGGSLVEFLSWPHERRIQAVGKYLLSPKIISLFNALCKFGELGESRSVMTECSSVDSDISSAFLQSPRKRKQRSLQACAVPTNKLLFSDSLNQIPGDYAEHAEVFSPSKLRKFSDMDNTIPELPDVFTFDESLNMRSEGFSYQQKKHDVDAIPGNQVINDDFSNGLTPNNQAYNRRTGNMVDTFDLPWQPEFGGTHPSKSTFHTSRPSCSRTHSNPVFSTAFEINDDPGEWNISGGTKQTWKGLAHGGTVDDSYRYDMDNRYHEPRDEIMQHPASSLAFQKLDFGSHATSQGSCWEIDYLRQMSAKRKARQERSRCSNSPGMSIPRMRDSNSKILNPPPKESFRYRGDRDTPSRDQSPSIGTQHYGKGKEGAKAQNRRARKDFNVQPTSHKKRIEPSIDPTWTPIDKRARQKLSFVTYGKEKQSKLVWRNQNSPGVGCGFRKRFREEGT*