Gene Details:
- MSU gene ID: LOC_Os02g22020
- RAPdb gene ID: Os02g0325600
- Gene Symbol: NIGT1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Furthermore, the chlorophyll content that could be a marker of nitrogen utilization was found to be decreased in NIGT1 overexpressors of rice grown with nitrate medium but not with ammonium medium.
- Thus, we propose NIGT1 as a nitrate-inducible and autorepressible transcriptional repressor that may play a role in the nitrogen response in rice.
- Here we show that the supply of nitrate but not ammonium immediately induces the expression of a transcriptional repressor gene in rice, designated NIGT1 (Nitrate-Inducible, GARP-type Transcriptional Repressor 1).
- Consistently, nitrate-induced NIGT1 expression was found to be down-regulated after a transient peak during nitrate treatment, and the nitrate-induced expression of NIGT1 decreased in transgenic rice plants in which this gene was constitutively overexpressed.
- Taken together with the fact that the NIGT1-binding sites are conserved in promoter sequences of Arabidopsis NIGT1 homologs, our findings imply the presence of a time-dependent complex system for nitrate-responsive transcriptional regulation that is conserved in both monocots and dicots.
- Here we show that a Pi-starvation induced transcription factor NIGT1 (NITRATE-INDUCIBLE GARP-TYPE TRANSCRIPTIONAL REPRESSOR 1) controls plant growth and prevents a hyperresponse to Pi-starvation by directly repressing the expression of growth-related and Pi-signaling genes to achieve a balance between growth and response under a varying Pi environment.
- NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice.
- We further demonstrate that NIGT1 constrains shoot growth by repressing the expression of growth-related regulatory genes, including brassinolide signal transduction master regulator BZR1, cell division regulator CYCB1;1, and DNA replication regulator PSF3.
- Our findings reveal the function of NIGT1 in orchestrating plant growth and Pi-starvation signaling, and also provide evidence that NIGT1 acts as a safeguard to avoid hyperresponse during Pi-starvation stress in rice.
Function-related keywords:
- nitrogen , nitrate , transcription-factor , growth , shoot , stress , cell-division , plant-growth , signal-transduction , phosphate , Pi , pi , phosphate-starvation , transcriptional-repressor , phosphate-starvation-signaling
Literature:
- A nitrate-inducible GARP family gene encodes an auto-repressible transcriptional repressor in rice . DOI: 10.1093/pcp/pct007 ; PMID: 23324170
- NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice . DOI: 10.1111/jipb.13496 ; PMID: 37096648
Related News:
Gene Resources:
- NCBI ID: AK101809
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os02g22020.1
GCCCGTCCGTTCGATTCGACGACACCTTCATTTTTATTTTCTTCCTTGTGTAATAAGAAGACGACTAGTGGTAACAAAAAGATTCGCTCCCTACGCGACGCCCCGACCCCGATTCCCTTCGCTTCCTACTCCTTCCTCTTCCTTGTTCCTTCCTTCCTTCCTCACCCCACGAACGCGCACACCAACCTTTCCCATCCCTAGCTGCTGCCCTTCCATCGGATCCACGGATCGAGACCTGGCACGGCGGCGGAGGACGGGCCGGCGGAGATGGAGGTGGACCACGCGGACCGCGACGGCGCGCGGCGCCGGTGCCGCGAGTACCTGCTCGCGCTCGAGGAGGAGCGCCGCAAGATCCAGGTGTTCCAGCGGGAGCTCCCTCTCTGCTTCGACCTCGTCACCCAGACTATCGAGGGGATGAGGAGCCAGATGGACGCCGCCGGCAGCGAGGAGACGGTCAGCGACCAGGGCCCGCCGCCGGTGCTCGAGGAGTTCATCCCGCTCAAGCCCAGCCTCTCGCTGTCCTCCTCCGAGGAGGAGAGCACCCACGCCGACGCCGCCAAGTCAGGCAAGAAGGAGGAGGCCGAGACGTCGGAGAGGCATTCGTCGCCGCCGCCGCCGCCGCCGGAGGCCAAGAAGGTGACGCCGGATTGGCTCCAGTCCGTGCAGCTCTGGAGCCAAGAAGAACCCCAGCAGCCATCGTCTCCTAGCCCAACTCCTACCAAGGATTTACCGTGCAAGCCGGTGGCGCTGAACGCCAGGAAGGCCGGCGGAGCGTTCCAGCCGTTCGAGAAGGAGAAGCGCGCCGAGCTGCCGGCGTCGTCGACCACGGCCGCGGCGAGCTCGACCGTGGTCGGAGACAGCGGCGACAAGCCCACCGATGATGACACGGAGAAACACATGGAGACGGACAAGGACAACGACAAGGACGCCAAGGACAAGGACAAGGAAGGCCAGTCGCAGCCTCACCGGAAGCCTCGCCGGTGCTGGGCGCCGGAGCTCCACCGCCGCTTCCTGCAAGCGCTGCAGCAGCTGGGCGGGTCCCATGTAGCGACGCCCAAGCAGATCCGGGAGCTGATGAAGGTGGATGGCCTCACCAACGACGAGGTCAAGAGCCATTTGCAGAAGTATCGTCTACACACGAGGAGGCCGAGCTCGACGGGGCAGAGCAGCGCCGCAGCCGGCGTCCCCGCCCCGCCTGCGCCGCAGTTCGTCGTCGTCGGGAGCATCTGGGTACCCCCGCCGGAATACGCTGCCGCGGCCGCCGCACAGCAGCACGTGCAGCTTGCCGCCGCCGGCAATAATGCGTCCGGGAGCGCCAACCCCGTGTACGCTCCGGTGGCGATGCTGCCGGCAGGCTTGCAGCCGCATTCGCATCGGAAGCAGCACCAGCAGCAGCAGCAAGGACAGAGACATTCCGGGTCGGAAGGCCGGCGGAGCGGGGACGCCGGCGATGGCAGCTCGTCCTCCCCGGCCGTCTCGTCGTCGTCGCAGACCACCTCCGCTTGATTAGTGTAGATTCGTCGATTACATCATTATATGTACGTAGTACGAGAGTGCATCACATCAAAGTGCAGCTTGATTTTGGAGCTAGCTAGCTTAAATTAAGGGTTAATTACTGATTGCTTCGTGATCGCACACACCACATTTGCTGTTTTGTTTGTAAAAAAGATAATAAAATACATAAATATTAAGGAAACTCCATAGACATTAT
CDS Sequence
- >LOC_Os02g22020.1
ATGGAGGTGGACCACGCGGACCGCGACGGCGCGCGGCGCCGGTGCCGCGAGTACCTGCTCGCGCTCGAGGAGGAGCGCCGCAAGATCCAGGTGTTCCAGCGGGAGCTCCCTCTCTGCTTCGACCTCGTCACCCAGACTATCGAGGGGATGAGGAGCCAGATGGACGCCGCCGGCAGCGAGGAGACGGTCAGCGACCAGGGCCCGCCGCCGGTGCTCGAGGAGTTCATCCCGCTCAAGCCCAGCCTCTCGCTGTCCTCCTCCGAGGAGGAGAGCACCCACGCCGACGCCGCCAAGTCAGGCAAGAAGGAGGAGGCCGAGACGTCGGAGAGGCATTCGTCGCCGCCGCCGCCGCCGCCGGAGGCCAAGAAGGTGACGCCGGATTGGCTCCAGTCCGTGCAGCTCTGGAGCCAAGAAGAACCCCAGCAGCCATCGTCTCCTAGCCCAACTCCTACCAAGGATTTACCGTGCAAGCCGGTGGCGCTGAACGCCAGGAAGGCCGGCGGAGCGTTCCAGCCGTTCGAGAAGGAGAAGCGCGCCGAGCTGCCGGCGTCGTCGACCACGGCCGCGGCGAGCTCGACCGTGGTCGGAGACAGCGGCGACAAGCCCACCGATGATGACACGGAGAAACACATGGAGACGGACAAGGACAACGACAAGGACGCCAAGGACAAGGACAAGGAAGGCCAGTCGCAGCCTCACCGGAAGCCTCGCCGGTGCTGGGCGCCGGAGCTCCACCGCCGCTTCCTGCAAGCGCTGCAGCAGCTGGGCGGGTCCCATGTAGCGACGCCCAAGCAGATCCGGGAGCTGATGAAGGTGGATGGCCTCACCAACGACGAGGTCAAGAGCCATTTGCAGAAGTATCGTCTACACACGAGGAGGCCGAGCTCGACGGGGCAGAGCAGCGCCGCAGCCGGCGTCCCCGCCCCGCCTGCGCCGCAGTTCGTCGTCGTCGGGAGCATCTGGGTACCCCCGCCGGAATACGCTGCCGCGGCCGCCGCACAGCAGCACGTGCAGCTTGCCGCCGCCGGCAATAATGCGTCCGGGAGCGCCAACCCCGTGTACGCTCCGGTGGCGATGCTGCCGGCAGGCTTGCAGCCGCATTCGCATCGGAAGCAGCACCAGCAGCAGCAGCAAGGACAGAGACATTCCGGGTCGGAAGGCCGGCGGAGCGGGGACGCCGGCGATGGCAGCTCGTCCTCCCCGGCCGTCTCGTCGTCGTCGCAGACCACCTCCGCTTGA
Protein Sequence
- >LOC_Os02g22020.1
MEVDHADRDGARRRCREYLLALEEERRKIQVFQRELPLCFDLVTQTIEGMRSQMDAAGSEETVSDQGPPPVLEEFIPLKPSLSLSSSEEESTHADAAKSGKKEEAETSERHSSPPPPPPEAKKVTPDWLQSVQLWSQEEPQQPSSPSPTPTKDLPCKPVALNARKAGGAFQPFEKEKRAELPASSTTAAASSTVVGDSGDKPTDDDTEKHMETDKDNDKDAKDKDKEGQSQPHRKPRRCWAPELHRRFLQALQQLGGSHVATPKQIRELMKVDGLTNDEVKSHLQKYRLHTRRPSSTGQSSAAAGVPAPPAPQFVVVGSIWVPPPEYAAAAAAQQHVQLAAAGNNASGSANPVYAPVAMLPAGLQPHSHRKQHQQQQQGQRHSGSEGRRSGDAGDGSSSSPAVSSSSQTTSA*