Gene Details:
- MSU gene ID: LOC_Os02g17780
- RAPdb gene ID: Os02g0278700
- Gene Symbol: OsCPS OsCPS1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- The phylogenetic tree and expression analyses suggest that TaCPS3 is responsible for gibberellin biosynthesis, while TaCPS1 and TaCPS2 are possible functional homologs of diterpene cyclase genes OsCPS2 and OsCPS4 involved in phytoalexin biosynthesis in rice.
- The entcopalyl diphosphate synthase (OsCPS) genes, which encode enzymes at the branch point between GA and phytoalexin biosynthesis, were expressed differentially in gid1 relative to the wild type.
- Specifically, OsCPS1, which encodes an enzyme in the GA biosynthesis pathway, was down-regulated and OsCPS2 and OsCPS4, which encode enzymes in phytoalexin biosynthesis, were up-regulated in gid1.
- The expression levels of gibberellin (GA) biosynthetic genes including OsCPS1, OsKS1, OsKO1, OsKAO, OsGA20ox2/SD1 and OsGA2ox3 were significantly increased in d62 mutant.
- It has recently been shown that a loss-of-function mutation of OsCPS1, a gene encoding a putative ent-CDP synthase, results in a severely GA-deficient dwarf phenotype in rice.
- To understand their physiological roles, we examined the site of their biosynthesis by analyzing the expression pattern of a gene (OsCPS) encoding coparyl diphosphate synthase in developing rice flowers.
- Rice (Oryza sativa L.) has two ent-CDP synthase genes, OsCPS1 and OsCPS2.
- The results indicate that transcripts of the two ent-CDP synthase genes differentially localize in rice plants according to their distinct biological roles, OsCPS1 for growth and OsCPS2 for defence.
- It has been shown previously that loss-of-function OsCPS1 mutants display a severe dwarf phenotype caused by GA deficiency despite possessing another ent-CDP synthase gene, OsCPS2.
- It has been thought that OsCPS1 participates in GA biosynthesis, while OsCPS2 participates in the biosynthesis of phytoalexins, phytocassanes A-E, and oryzalexins A-F.
- Genome-wide association mapping and gene expression analysis identify OsCPS1 as a new candidate gene controlling early seedling length in rice.
- Population analysis across wild rice, indica and japonica, suggested that OsCPS1 may be under selection in japonica during domestication.
Function-related keywords:
- gibberellin , ga , dwarf , flower , ent-CDP-synthase , growth , GA , GA-deficiency , GA-biosynthesis , seedling , domestication
Literature:
- Identification and characterization of dwarf 62, a loss-of-function mutation in DLT/OsGRAS-32 affecting gibberellin metabolism in rice . DOI: 10.1007/s00425-010-1263-1 ; PMID: 20830595
- Expression pattern of the coparyl diphosphate synthase gene in developing rice anthers . DOI: 10.1271/bbb.68.1814 ; PMID: 15322373
- Cloning and characterization of cDNAs encoding ent-copalyl diphosphate synthases in wheat: insight into the evolution of rice phytoalexin biosynthetic genes . DOI: 10.1271/bbb.80781 ; PMID: 19270400
- gid1, a gibberellin-insensitive dwarf mutant, shows altered regulation of probenazole-inducible protein (PBZ1) in response to cold stress and pathogen attack . DOI: 10.1111/j.1365-3040.2005.01441.x ; PMID: 17080612
- Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis . DOI: 10.1111/j.1365-313X.2004.02175.x ; PMID: 15341631
- Transcripts of two ent-copalyl diphosphate synthase genes differentially localize in rice plants according to their distinct biological roles . DOI: 10.1093/jxb/eru424 ; PMID: 25336684
- Genome-wide association mapping and gene expression analysis identify OsCPS1 as a new candidate gene controlling early seedling length in rice . DOI: 10.3389/fpls.2022.976669 ; PMID: 36119573
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os02g17780.1
GCTCTCGCCTCCCGCATCGCATCTCCATCATCTCCCCATCCTCCTCTCTACTCGTGTCTTCCATTCCTCCATCCCTCGCGCGCATCTCCGACGAGCTCTCTACTCCCTCCTCCGCCGCCGACGATGATTCACCTCCACTCCCCGCCGACGGCGCCCGCCGCATTCGGCGGCGCCGGCTCGGCGGACTGGCGGCGGCGGCGGCGGTGGTCATGGTCGTCGTCGTCCCGCGCTCCGGTGGCTAAAGGTGGCCATCTTCGTCCGTGCGTTTGGCGGCGCGGCGGCGACGACGGCGGCGGCGAGGATCATCACGCCGACGGCGGCGGCGGCGGCGGAGGAGGAGCGGCGTGGAGGGCGCGGGCCACCACCGCCGGCGTGTCGAGCTCCAGCAGTACAGCCAAAGGGCTGCAAGCCAACATCATCGAACATGAGACCCCCCGGATCACGAAATGGCCCAATGAATCACGCGACCTCGACGATCACCAACAAAACAACGAGGCTGATGAGGAGGCAGATGATGAGCTGCAGCCACTGGTCGAGCAGGTGAGGTCGATGCTGTCGTCCATGGAGGACGGCGCGATCACCGCGTCGGCGTACGACACGGCGTGGGTGGCGCTGGTGCCGCGGCTGGACGGCGAGGGCGGCACGCAGTTCCCGGCCGCCGTGCGGTGGATCGTCGGCAGCCAGCTCGCCGACGGGTCGTGGGGCGACGAGGCGCTCTTCTCCGCCTACGACCGCGTCATCAACACCCTCGCCTGCGTCGTCGCCCTCACCAGATGGTCCCTCCACCATGACCAGTGCAAGCAAGGGCTTCAGTTTCTGAATCTGAACTTGTGGAGGTTAGCAGAGGAGGAGCCGGATACGATGCCGATTGGGTTTGAGATTGCATTCCCTTCTCTTGTGGAGGCAGCTAGGGGTTTGGGTATTGATTTCCCATATGATCACCCTGCTCTCAAGGGCATTTATGCAAACAGAGAACTCAAGCTTAAGAGGATTCCAAAGGACATGATGCATATAGTCCCAACTTCAATTCTGCATAGCCTTGAAGGGATGCCTGGGCTGGATTGGCAGAGGCTTCTGAAGCTCCAATGCAGTGATGGATCCTTCTTGTTCTCCCCTTCAGCTACTGCTTATGCTCTCATGCAGACCGGTGACAAGAAATGCTTCGCGTACATCGACAGGATCATTAAGAAATTCGACGGAGGCGTTCCGAACGTTTACCCGGTCGATCTTTTTGAGCACATATGGGTTGTCGATCGGTTGGAGCGTCTTGGGATATCGCGGTACTTCCAACGAGAGATTGAACAGAACATGGACTATGTCAACAGGCACTGGACTGAAGATGGGATTTGCTGGGCTAGGAACTCCAATGTAAAAGAAGTGGATGACACCGCTATGGCTTTCCGTCTACTACGCCTCCATGGATACAATGTATCACCAAGTGTGTTCAAGAATTTTGAGAAGGATGGGGAGTTCTTCTGTTTTGTGGGGCAATCAACTCAAGCAGTCACTGGGATGTATAACCTGAACAGAGCATCTCAGATAAGTTTTCCAGGAGAAGACATTTTGCAGCGTGCAAGGAATTTCTCATATGAGTTCCTTAGAGAAAGAGAAGCCCAGGGGACACTTCATGATAAATGGATCATCTCCAAGGACCTACCAGGAGAGGTACAATACACACTAGATTTTCCTTGGTATGCGAGCTTGCCACGCGTCGAGGCAAGAACATACATAGGTCAATATGGTGGAAATGATGACGTCTGGATTGGAAAGACACTCTACAGGATGCCAATTGTGAATAACGCTACATATCTCGAGTTGGCGAAACAGGATTTCAACCGTTGTCAAGCTCTACATCAGCATGAGTTGCAGGGTCTACAAAAGTGGTTCATTGAGAATGGCCTGGAAGCTTTTGGGATGACACCTGAAGATGTTTTGAGAGCTTATTTTTTGGCTGCCGCGTGCATTTTCGAACCAAACCGTGCCTCTGAGCGACTTGCATGGGCTAGAGTGTCAGTGCTGGCCAACACTATTTCTAGGCATTTTTACAGCGATATGTCAAGCATGAAAAGGATGGAGCGTTTCATGTGGAGCAGCCTCTATGAAGAAAATGGCAATGTTTTGGGGCTAGAAGGATATGCAAAAGATGGAATCCTTGCGAGGACACTTTGTCAACTTATAGATTTGTTGTCTCAAGAGACACCGCCAGTTCGAGAAGGTCAAAAGTGTATTCATAATCTCATAAGATGTGCTTGGATTGAATGGATGATGCAACAAATCAATATGAAGGATGGCAGATATGACAAAGGCAGAGTTATGCATCCAGGGTCATGCACTGTTCATAATAAAGAAACATGTTTACTTATTGCTCAAATTGTTGAAATTTGTGCTGGACGAATTGAGGAGGCAGCATCTATGATAAATAACACCGAAGGTTCTTGGTTTATTCAACTTGCTTCCTCTATTTGCGATTCTCTTCATGCCAAGATGTTACTTTCACAGGATACCAAGAAAAATGAGACAACAATAAATCAAATTGACAAGGAAATTGAGTTGGGTATGCAAGAACTTGCTCAATATCTTCTTCCAAGAGTTGATGATAGAAGAATTAACAACAAAACCAAGCAGACCTTCTTGAGCATTGTGAAAAGCTGTTACTATGCTGCCAATTGCTCACCACATATGCTTGACCAACACATTTCTGAAGTGATTTTTGAGCAAGTTATTTGAAATAAAGTTTAGGCAAATAGAGCATTTGTCAGATTGAATCGCATGTAAATATTTCTGTGCAGAAAAAATATGTAAAGAATGAGAGAGAACAAGCATATAAACAATAGTATTATTGTTGAAAGCTAACAATTTTTACATCAAGTGAATGATGTATCTCTGTATGGTTCTACATGTGGGACACATTTTCTATAAATTATTTATTTTGGGTTTGTTCTA
CDS Sequence
- >LOC_Os02g17780.1
ATGATTCACCTCCACTCCCCGCCGACGGCGCCCGCCGCATTCGGCGGCGCCGGCTCGGCGGACTGGCGGCGGCGGCGGCGGTGGTCATGGTCGTCGTCGTCCCGCGCTCCGGTGGCTAAAGGTGGCCATCTTCGTCCGTGCGTTTGGCGGCGCGGCGGCGACGACGGCGGCGGCGAGGATCATCACGCCGACGGCGGCGGCGGCGGCGGAGGAGGAGCGGCGTGGAGGGCGCGGGCCACCACCGCCGGCGTGTCGAGCTCCAGCAGTACAGCCAAAGGGCTGCAAGCCAACATCATCGAACATGAGACCCCCCGGATCACGAAATGGCCCAATGAATCACGCGACCTCGACGATCACCAACAAAACAACGAGGCTGATGAGGAGGCAGATGATGAGCTGCAGCCACTGGTCGAGCAGGTGAGGTCGATGCTGTCGTCCATGGAGGACGGCGCGATCACCGCGTCGGCGTACGACACGGCGTGGGTGGCGCTGGTGCCGCGGCTGGACGGCGAGGGCGGCACGCAGTTCCCGGCCGCCGTGCGGTGGATCGTCGGCAGCCAGCTCGCCGACGGGTCGTGGGGCGACGAGGCGCTCTTCTCCGCCTACGACCGCGTCATCAACACCCTCGCCTGCGTCGTCGCCCTCACCAGATGGTCCCTCCACCATGACCAGTGCAAGCAAGGGCTTCAGTTTCTGAATCTGAACTTGTGGAGGTTAGCAGAGGAGGAGCCGGATACGATGCCGATTGGGTTTGAGATTGCATTCCCTTCTCTTGTGGAGGCAGCTAGGGGTTTGGGTATTGATTTCCCATATGATCACCCTGCTCTCAAGGGCATTTATGCAAACAGAGAACTCAAGCTTAAGAGGATTCCAAAGGACATGATGCATATAGTCCCAACTTCAATTCTGCATAGCCTTGAAGGGATGCCTGGGCTGGATTGGCAGAGGCTTCTGAAGCTCCAATGCAGTGATGGATCCTTCTTGTTCTCCCCTTCAGCTACTGCTTATGCTCTCATGCAGACCGGTGACAAGAAATGCTTCGCGTACATCGACAGGATCATTAAGAAATTCGACGGAGGCGTTCCGAACGTTTACCCGGTCGATCTTTTTGAGCACATATGGGTTGTCGATCGGTTGGAGCGTCTTGGGATATCGCGGTACTTCCAACGAGAGATTGAACAGAACATGGACTATGTCAACAGGCACTGGACTGAAGATGGGATTTGCTGGGCTAGGAACTCCAATGTAAAAGAAGTGGATGACACCGCTATGGCTTTCCGTCTACTACGCCTCCATGGATACAATGTATCACCAAGTGTGTTCAAGAATTTTGAGAAGGATGGGGAGTTCTTCTGTTTTGTGGGGCAATCAACTCAAGCAGTCACTGGGATGTATAACCTGAACAGAGCATCTCAGATAAGTTTTCCAGGAGAAGACATTTTGCAGCGTGCAAGGAATTTCTCATATGAGTTCCTTAGAGAAAGAGAAGCCCAGGGGACACTTCATGATAAATGGATCATCTCCAAGGACCTACCAGGAGAGGTACAATACACACTAGATTTTCCTTGGTATGCGAGCTTGCCACGCGTCGAGGCAAGAACATACATAGGTCAATATGGTGGAAATGATGACGTCTGGATTGGAAAGACACTCTACAGGATGCCAATTGTGAATAACGCTACATATCTCGAGTTGGCGAAACAGGATTTCAACCGTTGTCAAGCTCTACATCAGCATGAGTTGCAGGGTCTACAAAAGTGGTTCATTGAGAATGGCCTGGAAGCTTTTGGGATGACACCTGAAGATGTTTTGAGAGCTTATTTTTTGGCTGCCGCGTGCATTTTCGAACCAAACCGTGCCTCTGAGCGACTTGCATGGGCTAGAGTGTCAGTGCTGGCCAACACTATTTCTAGGCATTTTTACAGCGATATGTCAAGCATGAAAAGGATGGAGCGTTTCATGTGGAGCAGCCTCTATGAAGAAAATGGCAATGTTTTGGGGCTAGAAGGATATGCAAAAGATGGAATCCTTGCGAGGACACTTTGTCAACTTATAGATTTGTTGTCTCAAGAGACACCGCCAGTTCGAGAAGGTCAAAAGTGTATTCATAATCTCATAAGATGTGCTTGGATTGAATGGATGATGCAACAAATCAATATGAAGGATGGCAGATATGACAAAGGCAGAGTTATGCATCCAGGGTCATGCACTGTTCATAATAAAGAAACATGTTTACTTATTGCTCAAATTGTTGAAATTTGTGCTGGACGAATTGAGGAGGCAGCATCTATGATAAATAACACCGAAGGTTCTTGGTTTATTCAACTTGCTTCCTCTATTTGCGATTCTCTTCATGCCAAGATGTTACTTTCACAGGATACCAAGAAAAATGAGACAACAATAAATCAAATTGACAAGGAAATTGAGTTGGGTATGCAAGAACTTGCTCAATATCTTCTTCCAAGAGTTGATGATAGAAGAATTAACAACAAAACCAAGCAGACCTTCTTGAGCATTGTGAAAAGCTGTTACTATGCTGCCAATTGCTCACCACATATGCTTGACCAACACATTTCTGAAGTGATTTTTGAGCAAGTTATTTGA
Protein Sequence
- >LOC_Os02g17780.1
MIHLHSPPTAPAAFGGAGSADWRRRRRWSWSSSSRAPVAKGGHLRPCVWRRGGDDGGGEDHHADGGGGGGGGAAWRARATTAGVSSSSSTAKGLQANIIEHETPRITKWPNESRDLDDHQQNNEADEEADDELQPLVEQVRSMLSSMEDGAITASAYDTAWVALVPRLDGEGGTQFPAAVRWIVGSQLADGSWGDEALFSAYDRVINTLACVVALTRWSLHHDQCKQGLQFLNLNLWRLAEEEPDTMPIGFEIAFPSLVEAARGLGIDFPYDHPALKGIYANRELKLKRIPKDMMHIVPTSILHSLEGMPGLDWQRLLKLQCSDGSFLFSPSATAYALMQTGDKKCFAYIDRIIKKFDGGVPNVYPVDLFEHIWVVDRLERLGISRYFQREIEQNMDYVNRHWTEDGICWARNSNVKEVDDTAMAFRLLRLHGYNVSPSVFKNFEKDGEFFCFVGQSTQAVTGMYNLNRASQISFPGEDILQRARNFSYEFLREREAQGTLHDKWIISKDLPGEVQYTLDFPWYASLPRVEARTYIGQYGGNDDVWIGKTLYRMPIVNNATYLELAKQDFNRCQALHQHELQGLQKWFIENGLEAFGMTPEDVLRAYFLAAACIFEPNRASERLAWARVSVLANTISRHFYSDMSSMKRMERFMWSSLYEENGNVLGLEGYAKDGILARTLCQLIDLLSQETPPVREGQKCIHNLIRCAWIEWMMQQINMKDGRYDKGRVMHPGSCTVHNKETCLLIAQIVEICAGRIEEAASMINNTEGSWFIQLASSICDSLHAKMLLSQDTKKNETTINQIDKEIELGMQELAQYLLPRVDDRRINNKTKQTFLSIVKSCYYAANCSPHMLDQHISEVIFEQVI*