Gene Details:

• MSU gene ID: LOC_Os02g13810
• RAPdb gene ID: Os02g0232100
• Gene Symbol: HEI10
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Mice HEI10(mei4) mutant displays no obvious defect other than meiotic failure from an absence of chiasmata.
• In this study, we characterize rice HEI10 by map-based cloning and explore its function during meiotic recombination.
• HEI10 protein displays a highly dynamic localization on the meiotic chromosomes.
• Together our results suggest that HEI10 is the homolog of budding yeast Zip3 and Caenorhabditis elegans ZHP-3, and may specifically promote class I CO formation through modification of various meiotic components.
• The role of rice HEI10 in the formation of meiotic crossovers.
• OsMSH5 can be loaded onto meiotic chromosomes in Oszip4, Osmer3, and HEI10.
• HEI10 was first described in human as a RING domain-containing protein that regulates cell cycle and cell invasion.

Function-related keywords:

• meiotic ,  cell-cycle

Literature:

• The role of rice HEI10 in the formation of meiotic crossovers .  DOI:  10.1371/journal.pgen.1002809 ;  PMID:  22792078
• The role of OsMSH5 in crossover formation during rice meiosis .  DOI:  10.1093/mp/sss145 ;  PMID:  23220939

Related News:

Gene Resources:

• NCBI ID: AK100854  , AK108775
• UniProt accessions:

Sequences: