Gene Details:

• MSU gene ID: LOC_Os02g12290
• RAPdb gene ID: Os02g0214300
• Gene Symbol: TMS5
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Development of Commercial Thermo-sensitive Genic Male Sterile Rice Accelerates Hybrid Rice Breeding Using the CRISPR/Cas9-mediated TMS5 Editing System.
• RESULTS: Here, thermo-sensitive genic male sterility (TGMS) was induced by employing the CRISPR/Cas9 gene editing technology to modify the gene TMS5.
• Generation of a new thermo-sensitive genic male sterile rice line by targeted mutagenesis of TMS5 gene through CRISPR/Cas9 system.
• In the present study, a super grain quality line, GXU 47, was used to generate a new TGMS line with specific mutations in a major TGMS gene TMS5 generated with CRISPR/Cas9-mediated genome editing in order to improve the rice quality of two-line hybrids.
• CRISPR/Cas9-Induced Mutagenesis of TMS5 Confers Thermosensitive Genic Male Sterility by Influencing Protein Expression in Rice (Oryza sativa L.).
• The present study results prove that it is feasible and efficient to generate an excellent mutant line with CRISPR/Cas9, which provides a novel molecular mechanism of male sterility caused by the mutation of TMS5.

Function-related keywords:

• development ,  sterile ,  breeding ,  sterility ,  male-sterility ,  grain ,  grain-quality ,  quality

Literature:

• RNase Z(S1) processes UbL40 mRNAs and controls thermosensitive genic male sterility in rice .  DOI:  10.1038/ncomms5884 ;  PMID:  25208476
• Development of Commercial Thermo-sensitive Genic Male Sterile Rice Accelerates Hybrid Rice Breeding Using the CRISPR/Cas9-mediated TMS5 Editing System .  DOI:  10.1038/srep37395 ;  PMID:  27874087
• Generation of a new thermo-sensitive genic male sterile rice line by targeted mutagenesis of TMS5 gene through CRISPR/Cas9 system .  DOI:  10.1186/s12870-019-1715-0 ;  PMID:  30894127
• CRISPR/Cas9-Induced Mutagenesis of TMS5 Confers Thermosensitive Genic Male Sterility by Influencing Protein Expression in Rice (Oryza sativa L.) .  DOI:  10.3390/ijms23158354 ;  PMID:  35955484

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: