Gene Details:
- MSU gene ID: LOC_Os02g08500
- RAPdb gene ID: Os02g0182100
- Gene Symbol: LEPTO1 OsRR24 DLC1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Although meiosis initiates normally, as indicated by staining of the centromere-specific histone CENH3, the meiotic chromosomes in LEPTO1 mutant pollen mother cells (PMCs) fail to form the thin thread-like structures that are typical of leptotene chromosomes in wild-type PMCs.
- LEPTO1 is also essential for programmed cell death in tapetal cells.
- Furthermore, LEPTO1 mutants fail to form chromosomal double-strand breaks, do not recruit meiosis-specific proteins to the meiotic chromosomes, and show disrupted callose deposition.
- DLC1 is strongly expressed in the pollen mother cells (PMCs) and tapetum and encodes a nucleus-located rice type-B response regulator (RR) with transcriptional activity.
- Further investigations show that DLC1 interacts with all five putative rice histidine phosphotransfer proteins (HPs) in yeast and planta cells, suggesting a possible participation of the two-component signalling systems (TCS) in rice meiosis.
- Our results demonstrate that DLC1 is required for rice meiosis and fertility, providing useful information for the role of TCS in rice meiosis.
- The DLC1 mutant is sterile in both male and female gametophytes due to an earlier defect in the leptotene chromosome and subsequent abnormalities at later stages.
Function-related keywords:
Literature:
- The OsRR24/LEPTO1 Type-B Response Regulator is Essential for the Organization of Leptotene Chromosomes in Rice Meiosis . DOI: 10.1105/tpc.18.00479 ; PMID: 30538156
- Defective Leptotene Chromosome 1 (DLC1) encodes a type-B response regulator and is required for rice meiosis . DOI: 10.1111/tpj.14344 ; PMID: 31004552
- Reproductive cells and peripheral parietal cells collaboratively participate in meiotic fate acquisition in rice anthers . DOI: 10.1111/tpj.15461 ; PMID: 34397127
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os02g08500.1
ATTCCATTTACCCAATCCGCGATCCATCCATCATCCCCTACCTCTCGCTCTCTCTCTCCTCTCCTCTCCTCTTATTATCATCGCATCCATCCCGCACTTCTCTCTCTTTGGTGGTGGTGCTCGCTCTCGCTCACCCTGCTTTGACCTTTGGATTTTTATTTTTAAGGATCCAAGAAAGTGCTGTTTCTTGGGTTGCTTGGAGGTGGAGGAGTTTGGGAGATTGTTTGTGTTTGATTGATTGGTTGATTGATTGGAGGAAGATGACGGTGGAGGAGAGGCAGGGGAGGGTGGGAGGCCATGGTGTGAGCGGCGGCGGCGGCGGGAGAGACCAGTTCCCGGTCGGCATGCGGGTGCTCGCCGTCGACGACGACCCCACCTGCCTCAAGATCCTCGAGAACCTCCTGCTTCGATGCCAGTATCACGTGACAACAACTGGTCAGGCGGCCACGGCCCTGAAGCTGCTCAGGGAGAACAAGGACCAGTTTGACCTGGTGATCAGCGACGTCCACATGCCGGACATGGATGGCTTCAAACTCCTTGAGCTTGTCGGCCTCGAGATGGACCTCCCAGTCATTATGTTGTCTGCGAACGGGGAAACACAAACTGTCATGAAGGGTATAACCCATGGTGCATGTGACTATCTTCTGAAGCCAGTGCGTCTTGAGCAGCTAAGGACGATATGGCAACATGTGATTAGGCGTAAGAATTGTGATGCTAAGAACCGTGGTAACGATGATGACGCTGGTCAGAAGGCACAGGGAATGAACAATGAAGGTGAGAGTATTGGTGCTAACCGCAACAAGAGGCAGTCACGGAAAAGTAGAGATGAGAATGGAGATGATGGTGATGATTCTGATGAGAACAGTAATGAGAATGGAGACTCATCAACACAGAAGAAGCCAAGGGTCGTGTGGTCTGTTGAGCTGCACCGAAAGTTTGTGGCTGCTGTTAACCAGCTTGGCATCGAGAAGGCTGTTCCAAAGAAAATATTGGATCTCATGAATGTAGAGAACATCACCAGGGAGAATGTTGCTAGTCATTTGCAGAAGTATCGGCTGTACCTTAAACGGTTGAGCACTGATGCAAGCAGGCAGGCTAACCTTGCAGCTGCATTTGGAGGAAGGAACCCTGCTTACATAAACATGAATTCATTTGGAAACTACAACGCATATGGTAGATACCGTACAGTCCCAACTGCTGGCCATACCCAGGCAAACAACATTCTTACTAGGATGAACTCCCCTTCTGCGTTTGGTGTTCATGGTTTGCTGCATTCACAGCCAATTCAGTTAGGACATGCCCAAAATAATCTGAGCACTTCACTGAATGATTTAGGAGGGCTTAATAATGGTAACATGATCAGAGGTGCACAGATGTCAACAATTCTAACTGGTCCTTCTGGTAACTCCTTTCCAAACATATCGAATGGTGCACCGCTGGCAACTGCAAACAGATCACTGCAACCTCTTGAGTCGAGCAATCAGCAACACCTTAGTCGGGTGCATTCATCTTCTGCAGATCCATTTAGCACACTTGTTGGTGAGTCTCCCCAGTTTCCTGATCTTGGAAGAACCACCAATACTTGGCAAACTGCGGTTCCATCCAACATTCAGGATCGTGGTCACAATGATAACATGTCGCAAGCCACCCTGCATATGAATGGCCCCAAAATTGAACCTGTCTCAAGCTTCACATCATCCAATCAGATTCCGCTGCTGGGAAATGAGATGCAGGGCCAAGTAGCATCACTAGCTAGCAATGTTCCAATAGCATTCAATCAGGACACATCACCATTCAACTATGGAAGCAGCACAAACTCAAGAGACATGCTAAATAACAGCCATGTATTTAGTAACTCCAGCATCAACACATCGTTGCCCAACCTTAGCTTAGACAATCCGGCTGTACCAAGGCAGACACTGGATCGTGGGAATACGGGCATTGTTTCTCCCATGCAAGATGGAAGGATTCATCACCAAGCTGTTAGCAATCAGCTAAACTATAATGACGATCTTATGCGGACAACTGGGCTGCAAAGGGGTCTCAGTGGTGGTCTAGATGACATTGTTGTTGACATGTTTAGGCCGGACCGCGAAGACGACGGCGTTCCTTACATCGATGGGGACTGGGAGCTGGTCTAGCCAGCCTCCATTTCAATCATTAGTCCGCGTACGAGGTTTTTCTGCATTCGCGGTGTCGGCTGCTGATTGGTCCATGCTCACTTGTCAGCACAAAGTGGTGTTCATAGTGGCTAGCCTTCATCACAAGTGCATTTCACATTTGGCTTCTTTTTTCAGCTTAGTGATTATTAGTTGGCCAGTCAGTCTGTGAAATTTATGTGGAGAAACGGCTATGTGGTGTGTTTTTATCATGACTTATACTATAATAACTATGTTAGTTCAGGTATAACCGGTTATCCTGATAATATAGTATGCTTGGTAAAATTCTCGTTAATCATCGAAATTCTCTTGGCTCTTTAATCTTT
CDS Sequence
- >LOC_Os02g08500.1
ATGACGGTGGAGGAGAGGCAGGGGAGGGTGGGAGGCCATGGTGTGAGCGGCGGCGGCGGCGGGAGAGACCAGTTCCCGGTCGGCATGCGGGTGCTCGCCGTCGACGACGACCCCACCTGCCTCAAGATCCTCGAGAACCTCCTGCTTCGATGCCAGTATCACGTGACAACAACTGGTCAGGCGGCCACGGCCCTGAAGCTGCTCAGGGAGAACAAGGACCAGTTTGACCTGGTGATCAGCGACGTCCACATGCCGGACATGGATGGCTTCAAACTCCTTGAGCTTGTCGGCCTCGAGATGGACCTCCCAGTCATTATGTTGTCTGCGAACGGGGAAACACAAACTGTCATGAAGGGTATAACCCATGGTGCATGTGACTATCTTCTGAAGCCAGTGCGTCTTGAGCAGCTAAGGACGATATGGCAACATGTGATTAGGCGTAAGAATTGTGATGCTAAGAACCGTGGTAACGATGATGACGCTGGTCAGAAGGCACAGGGAATGAACAATGAAGGTGAGAGTATTGGTGCTAACCGCAACAAGAGGCAGTCACGGAAAAGTAGAGATGAGAATGGAGATGATGGTGATGATTCTGATGAGAACAGTAATGAGAATGGAGACTCATCAACACAGAAGAAGCCAAGGGTCGTGTGGTCTGTTGAGCTGCACCGAAAGTTTGTGGCTGCTGTTAACCAGCTTGGCATCGAGAAGGCTGTTCCAAAGAAAATATTGGATCTCATGAATGTAGAGAACATCACCAGGGAGAATGTTGCTAGTCATTTGCAGAAGTATCGGCTGTACCTTAAACGGTTGAGCACTGATGCAAGCAGGCAGGCTAACCTTGCAGCTGCATTTGGAGGAAGGAACCCTGCTTACATAAACATGAATTCATTTGGAAACTACAACGCATATGGTAGATACCGTACAGTCCCAACTGCTGGCCATACCCAGGCAAACAACATTCTTACTAGGATGAACTCCCCTTCTGCGTTTGGTGTTCATGGTTTGCTGCATTCACAGCCAATTCAGTTAGGACATGCCCAAAATAATCTGAGCACTTCACTGAATGATTTAGGAGGGCTTAATAATGGTAACATGATCAGAGGTGCACAGATGTCAACAATTCTAACTGGTCCTTCTGGTAACTCCTTTCCAAACATATCGAATGGTGCACCGCTGGCAACTGCAAACAGATCACTGCAACCTCTTGAGTCGAGCAATCAGCAACACCTTAGTCGGGTGCATTCATCTTCTGCAGATCCATTTAGCACACTTGTTGGTGAGTCTCCCCAGTTTCCTGATCTTGGAAGAACCACCAATACTTGGCAAACTGCGGTTCCATCCAACATTCAGGATCGTGGTCACAATGATAACATGTCGCAAGCCACCCTGCATATGAATGGCCCCAAAATTGAACCTGTCTCAAGCTTCACATCATCCAATCAGATTCCGCTGCTGGGAAATGAGATGCAGGGCCAAGTAGCATCACTAGCTAGCAATGTTCCAATAGCATTCAATCAGGACACATCACCATTCAACTATGGAAGCAGCACAAACTCAAGAGACATGCTAAATAACAGCCATGTATTTAGTAACTCCAGCATCAACACATCGTTGCCCAACCTTAGCTTAGACAATCCGGCTGTACCAAGGCAGACACTGGATCGTGGGAATACGGGCATTGTTTCTCCCATGCAAGATGGAAGGATTCATCACCAAGCTGTTAGCAATCAGCTAAACTATAATGACGATCTTATGCGGACAACTGGGCTGCAAAGGGGTCTCAGTGGTGGTCTAGATGACATTGTTGTTGACATGTTTAGGCCGGACCGCGAAGACGACGGCGTTCCTTACATCGATGGGGACTGGGAGCTGGTCTAG
Protein Sequence
- >LOC_Os02g08500.1
MTVEERQGRVGGHGVSGGGGGRDQFPVGMRVLAVDDDPTCLKILENLLLRCQYHVTTTGQAATALKLLRENKDQFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSANGETQTVMKGITHGACDYLLKPVRLEQLRTIWQHVIRRKNCDAKNRGNDDDAGQKAQGMNNEGESIGANRNKRQSRKSRDENGDDGDDSDENSNENGDSSTQKKPRVVWSVELHRKFVAAVNQLGIEKAVPKKILDLMNVENITRENVASHLQKYRLYLKRLSTDASRQANLAAAFGGRNPAYINMNSFGNYNAYGRYRTVPTAGHTQANNILTRMNSPSAFGVHGLLHSQPIQLGHAQNNLSTSLNDLGGLNNGNMIRGAQMSTILTGPSGNSFPNISNGAPLATANRSLQPLESSNQQHLSRVHSSSADPFSTLVGESPQFPDLGRTTNTWQTAVPSNIQDRGHNDNMSQATLHMNGPKIEPVSSFTSSNQIPLLGNEMQGQVASLASNVPIAFNQDTSPFNYGSSTNSRDMLNNSHVFSNSSINTSLPNLSLDNPAVPRQTLDRGNTGIVSPMQDGRIHHQAVSNQLNYNDDLMRTTGLQRGLSGGLDDIVVDMFRPDREDDGVPYIDGDWELV*