Information report for OsLKP2
Gene Details
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Functional Descriptions
- Under drought conditions, total wax loads on the leaf surface increased by approximately 10% in OsLKP2-1 and OsLKP2-2 compared to the wild type, and the transcript levels of cuticular wax biosynthesis genes were upregulated in the OsLKP2 mutants.
- OsLKP2 knockdown (OsLKP2-1) and knockout (OsLKP2-2) mutants exhibited enhanced drought tolerance.
- Among ZEITLUPE family genes, OsLKP2 expression specifically increased under dehydration stress.
- Yeast two-hybrid, bimolecular fluorescence complementation, and coimmunoprecipitation assays revealed that OsLKP2 interacts with GIGANTEA (OsGI) in the nucleus.
Functional Keywords
Literature and News
- Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis . DOI: 10.15252/embj.2020105086 ; PMID: 33347628
- Suppression of cuticular wax biosynthesis mediated by rice LOV KELCH REPEAT PROTEIN 2 supports a negative role in drought stress tolerance . DOI: 10.1111/pce.14549 ; PMID: 36683564
Gene Resources
- UniProt: B7F9U6
- EMBL: AK242967, AP014958
- AlphaFoldDB: B7F9U6
- EnsemblPlants: Os02t0150800-01
- Gramene: Os02t0150800-01
- Orthologous matrix: CITGSRM
- InterPro: IPR000014, IPR001810, IPR011043
- PANTHER: PTHR46175, PTHR46175:SF1
- SUPFAM: SSF50965, SSF55785, SSF81383
- PROSITE: PS50112, PS50181
- Gene3D: 1.20.1280.50, 2.120.10.80, 3.30.450.20
- OrthoDB: B7F9U6
- SWISS-MODEL: B7F9U6
- Conserved Domain Database: cd00130, cd22154
Homologs
- Brachypodium distachyon: BRADI_3g04040v3
- Saccharum spontaneum: Sspon.04G0018300-1A
- Setaria italica: SETIT_016664mg
- Setaria viridis: SEVIR_1G085500v2
- Zea mays: GRMZM2G147800
Sequences
cDNA Sequence
- >LOC_Os02g05700.1
GTCCACTCGTTCGTCGCTTGCCGCTTCGTCTTCCTCCTCCCACCCACGAATTAATCCTCCTCCATTTTTGCTAATCCCGACCTCTCTCCCTCGCTAATCCGCCGCGACGCGCACGCGCGCGCAGTACAAATCCGCGCCGCCGACCTCGCCTCGCCGAGCTTGCGAGGTGGTTCCCCGTTCGGCCCCCGGGGGGCCCGCCATGGGCTAGGGTTTGCGGGCGATGGAGTGGGACAGCGACTCGGAGGGGAGCGGAGACGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGGGGTTGAGGTGGGGGGAGGTGGGGATGGGGGCGTGGGCGTGGGAGTCGGTGGGGGATTCGCGCTGGCGATCGAGGGGGTGCTGGGCGCGTGCGGGCTGGTGGTGTCGGACGCGCTGGAGCCGGATTTCCCCATCATCTACGTCAACCGCGGCTTCGAGGACGCCACCGGGTACCGCGCCGAGGAGGTGCTCGGGAGGAACTGTCGATTCTTGCAGTGTAGAGGACCATTTGCTAAGAGGAGACATCCCCTTGTTGATACTACAGTAGTTACTGACATTCGGAGATGCTTAGAGGAAGGCACTGTGTTCCAGGGCGATCTGCTGAACTTTAGGAAAGATGGTTCTCCATTCATGGCAAAGCTCCAGTTAACACCCATTTATGGAGATGACGAAACAATAACCCACTATATGGGCATGCAGTTCTTCAATGACTCTAATGTTGATTTGGGGCCATTGTCTGTCTCTACAACAAAGGAGATTGTGAGATCTACTTTGATTACACCAGATAACACCATCCGACCAAGTCCAATGGGGAAGGGCTTCTGCTCAGAGCATTCTGATCTTTTCCTATTGAGTGATGAGGTACTTTGCCAGAAGATCCTATCAAGATTATCGCCCAGGGATATAGCATCTGTAAACTCTGTATGTAAACGGCTGTACCACTTAACAAGGAATGACGACCTTTGGAGAATGGTTTGTCAGAATGCATGGGGCAGTGAAGCAACTCAAGTTCTTGAGACTGTGGCTGGAACAAGAAGTTTGGCATGGGGGCGGTTAGCAAGAGAGTTGACCACCCTGGAAGCTGTCACCTGGAGGAAATTGACTGTTGGGGGTGCAGTGGAGCCTTCTCGCTGCAACTTCAGCGCTTGTGCGGCAGGGAACCGTGTTGTCCTTTTTGGAGGGGAAGGTGTTAACATGCAGCCAATGAATGATACATTTGTGCTTGATTTGAATGCCAGCAAGCCAGAATGGAGGCACATCAATGTGAGATCGGCTCCTCCTGGGCGCTGGGGTCATACCCTTTCTTGCCTAAATGGATCACGGTTGGTTTTGTTTGGTGGTTGTGGAAGGCAGGGCCTGCTCAATGATGTGTTCATGTTGGATTTGGATGCACAGCAACCAACTTGGCGTGAGATTCCTGGCCTTGCACCACCAGTTCCACGGTCATGGCATAGTTCTTGCACATTGGATGGAACAAAATTGGTGGTATCTGGTGGCTGTGCTGATTCTGGTGTGCTTCTCAGTGACACGTATCTTTTGGATGTAACAATGGAAAGACCTGTTTGGAGGGAGATACCTGCATCTTGGACTCCACCTTGTAGATTGGGGCACTCGCTCTCTGTCTACGATGGCAGGAAAATCCTGATGTTTGGTGGTCTTGCTAAAAGCGGTCCTCTACGACTAAGGTCTAATGATGTGTTCACATTGGATTTAAGTGAAAATAAGCCATGCTGGCGGTGTATCACCGGCAGTGGAATGCCAGGAGCCAGTAATCCAGCTGGAGTTGGTCCACCCCCTCGCCTTGACCATGTCGCTGTGAGCCTTCCTGGAGGGAGAATTTTGATATTTGGTGGATCAGTGGCAGGTCTTCACTCCGCTTCAAAGCTTTACCTGCTGGATCCGACTGAAGAGAAGCCTACCTGGAGGATACTGAATGTTCCTGGCCGCCCTCCGCGATTTGCCTGGGGCCACAGTACCTGTGTTGTGGGAGGTACAAAGGCGATAGTTCTTGGAGGACAAACTGGAGAGGAGTGGACACTAACTGAACTGCATGAGCTTTCTCTGGTAAGCTCTTTAGTCTGAGGATGGAAGTCAAGTCCCCAGCAGGCTTCCAGCTTCATTGAAGTGATGATGTATACAGAGAGAAGCTATTGTTTTCATTTGACCGAAGCCTGGACATTTTCACCGTTGAAGCCACACAGAAACACAATTGAAATGTGCAAGCAAAATGTTTCCTACACTCAACCAAAAGGATCTGGAATTGTATAGTTGGAAGCTCTGATGCAATGCAACAAGCATGCTCTTCAAAGGCCAAAATGATAGTGATGATGCTGTACTGATCCAATATTTCTGATAAATTGTTCGATCTTTTGTTGAACATGCAAAACTGTTCGATTAGTTGTACACCATTTTTTTTTCTCTGGCAATACATTTAGTGTCAATTACCAAAGGACACCATATCTGCAGAAATCACCCCCCCCCCCCTCTTTCTCTCTCCTCTCTCACATGTGTTGTATGTTTAATCTTTAAACATTGTGATGACAATGTCTGTTCACATAGACCACACGGTTATACTTTTGTAACTTTGATTGTAGCTGAAAGCACCTGGATTGATCATTGGAAAACATGGAGATTTTGCTTCCATACA - >LOC_Os02g05700.2
GTCCACTCGTTCGTCGCTTGCCGCTTCGTCTTCCTCCTCCCACCCACGAATTAATCCTCCTCCATTTTTGCTAATCCCGACCTCTCTCCCTCGCTAATCCGCCGCGACGCGCACGCGCGCGCAGTACAAATCCGCGCCGCCGACCTCGCCTCGCCGAGCTTGCGAGGTGGTTCCCCGTTCGGCCCCCGGGGGGCCCGCCATGGGCTAGGGTTTGCGGGCGATGGAGTGGGACAGCGACTCGGAGGGGAGCGGAGACGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGGGGTTGAGGTGGGGGGAGGTGGGGATGGGGGCGTGGGCGTGGGAGTCGGTGGGGGATTCGCGCTGGCGATCGAGGGGGTGCTGGGCGCGTGCGGGCTGGTGGTGTCGGACGCGCTGGAGCCGGATTTCCCCATCATCTACGTCAACCGCGGCTTCGAGGACGCCACCGGGTACCGCGCCGAGGAGGTGCTCGGGAGGAACTGTCGATTCTTGCAGTGTAGAGGACCATTTGCTAAGAGGAGACATCCCCTTGTTGATACTACAGTAGTTACTGACATTCGGAGATGCTTAGAGGAAGGCACTGTGTTCCAGGGCGATCTGCTGAACTTTAGGAAAGATGGTTCTCCATTCATGGCAAAGCTCCAGTTAACACCCATTTATGGAGATGACGAAACAATAACCCACTATATGGGCATGCAGTTCTTCAATGACTCTAATGTTGATTTGGGGCCATTGTCTGTCTCTACAACAAAGGAGATTGTGAGATCTACTTTGATTACACCAGATAACACCATCCGACCAAGTCCAATGGGGAAGGGCTTCTGCTCAGAGCATTCTGATCTTTTCCTATTGAGTGATGAGGTACTTTGCCAGAAGATCCTATCAAGATTATCGCCCAGGGATATAGCATCTGTAAACTCTGTATGTAAACGGCTGTACCACTTAACAAGGAATGACGACCTTTGGAGAATGGTTTGTCAGAATGCATGGGGCAGTGAAGCAACTCAAGTTCTTGAGACTGTGGCTGGAACAAGAAGTTTGGCATGGGGGCGGTTAGCAAGAGAGTTGACCACCCTGGAAGCTGTCACCTGGAGGAAATTGACTGTTGGGGGTGCAGTGGAGCCTTCTCGCTGCAACTTCAGCGCTTGTGCGGCAGGGAACCGTGTTGTCCTTTTTGGAGGGGAAGGTGTTAACATGCAGCCAATGAATGATACATTTGTGCTTGATTTGAATGCCAGCAAGCCAGAATGGAGGCACATCAATGTGAGATCGGCTCCTCCTGGGCGCTGGGGTCATACCCTTTCTTGCCTAAATGGATCACGGTTGGTTTTGTTTGGTGGTTGTGGAAGGCAGGGCCTGCTCAATGATGTGTTCATGTTGGATTTGGATGCACAGCAACCAACTTGGCGTGAGATTCCTGGCCTTGCACCACCAGTTCCACGGTCATGGCATAGTTCTTGCACATTGGATGGAACAAAATTGGTGGTATCTGGTGGCTGTGCTGATTCTGGTGTGCTTCTCAGTGACACGTATCTTTTGGATGTAACAATGGAAAGACCTGTTTGGAGGGAGATACCTGCATCTTGGACTCCACCTTGTAGATTGGGGCACTCGCTCTCTGTCTACGATGGCAGGAAAATCCTGATGTTTGGTGGTCTTGCTAAAAGCGGTCCTCTACGACTAAGGTCTAATGATGTGTTCACATTGGATTTAAGTGAAAATAAGCCATGCTGGCGGTGTATCACCGGCAGTGGAATGCCAGGAGCCAGTAATCCAGCTGGAGTTGGTCCACCCCCTCGCCTTGACCATGTCGCTGTGAGCCTTCCTGGAGGGAGAATTTTGATATTTGGTGGATCAGTGGCAGGTCTTCACTCCGCTTCAAAGCTTTACCTGCTGGATCCGACTGAAGAGAAGCCTACCTGGAGGATACTGAATGTTCCTGGCCGCCCTCCGCGATTTGCCTGGGGCCACAGTACCTGTGTTGTGGGAGGTACAAAGGCGATAGTTCTTGGAGGACAAACTGGAGAGGAGTGGACACTAACTGAACTGCATGAGCTTTCTCTGGTAAGCTCTTTAGTCTGAGGATGGAAGTCAAGTCCCCAGCAGGCTTCCAGCTTCATTGAAGTGATGATGTATACAGAGAGAAGCTATTGTTTTCATTTGACCGAAGCCTGGACATTTTCACCGTTGAAGCCACACAGAAACACAATTGAAATGTGCAAGCAAAATGTTTCCTACACTCAACCAAAAGGATCTGGAATTGTATAGTTGGAAGCTCTGATGCAATGCAACAAGCATGCTCTTCAAAGGCCAAAATGATAGTGATGATGCTGTACTGATCCAATATTTCTGATAAATTGTTCGATCTTTTGTTGAACATGCAAAACTGTTCGATTAGTTGTACACCATTTTTTTTTCTCTGGCAATACATTTAGTGTCAATTACCAAAGGACACCATATCTGCAGAAATCACCCCCCCCCCCCTCTTTCTCTCTCCTCTCTCACATGTGTTGTATGTTTAATCTTTAAACATTGTGATGACAATGTCTGTTCACATAGACCACACGGTTATACTTTTGTAACTTTGATTGTAGCTGAAAGCACCTGGATTGATCATTGGAAAACATGGAGATTTTGCTTCCATACA
CDS Sequence
- >LOC_Os02g05700.1
ATGGAGTGGGACAGCGACTCGGAGGGGAGCGGAGACGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGGGGTTGAGGTGGGGGGAGGTGGGGATGGGGGCGTGGGCGTGGGAGTCGGTGGGGGATTCGCGCTGGCGATCGAGGGGGTGCTGGGCGCGTGCGGGCTGGTGGTGTCGGACGCGCTGGAGCCGGATTTCCCCATCATCTACGTCAACCGCGGCTTCGAGGACGCCACCGGGTACCGCGCCGAGGAGGTGCTCGGGAGGAACTGTCGATTCTTGCAGTGTAGAGGACCATTTGCTAAGAGGAGACATCCCCTTGTTGATACTACAGTAGTTACTGACATTCGGAGATGCTTAGAGGAAGGCACTGTGTTCCAGGGCGATCTGCTGAACTTTAGGAAAGATGGTTCTCCATTCATGGCAAAGCTCCAGTTAACACCCATTTATGGAGATGACGAAACAATAACCCACTATATGGGCATGCAGTTCTTCAATGACTCTAATGTTGATTTGGGGCCATTGTCTGTCTCTACAACAAAGGAGATTGTGAGATCTACTTTGATTACACCAGATAACACCATCCGACCAAGTCCAATGGGGAAGGGCTTCTGCTCAGAGCATTCTGATCTTTTCCTATTGAGTGATGAGGTACTTTGCCAGAAGATCCTATCAAGATTATCGCCCAGGGATATAGCATCTGTAAACTCTGTATGTAAACGGCTGTACCACTTAACAAGGAATGACGACCTTTGGAGAATGGTTTGTCAGAATGCATGGGGCAGTGAAGCAACTCAAGTTCTTGAGACTGTGGCTGGAACAAGAAGTTTGGCATGGGGGCGGTTAGCAAGAGAGTTGACCACCCTGGAAGCTGTCACCTGGAGGAAATTGACTGTTGGGGGTGCAGTGGAGCCTTCTCGCTGCAACTTCAGCGCTTGTGCGGCAGGGAACCGTGTTGTCCTTTTTGGAGGGGAAGGTGTTAACATGCAGCCAATGAATGATACATTTGTGCTTGATTTGAATGCCAGCAAGCCAGAATGGAGGCACATCAATGTGAGATCGGCTCCTCCTGGGCGCTGGGGTCATACCCTTTCTTGCCTAAATGGATCACGGTTGGTTTTGTTTGGTGGTTGTGGAAGGCAGGGCCTGCTCAATGATGTGTTCATGTTGGATTTGGATGCACAGCAACCAACTTGGCGTGAGATTCCTGGCCTTGCACCACCAGTTCCACGGTCATGGCATAGTTCTTGCACATTGGATGGAACAAAATTGGTGGTATCTGGTGGCTGTGCTGATTCTGGTGTGCTTCTCAGTGACACGTATCTTTTGGATGTAACAATGGAAAGACCTGTTTGGAGGGAGATACCTGCATCTTGGACTCCACCTTGTAGATTGGGGCACTCGCTCTCTGTCTACGATGGCAGGAAAATCCTGATGTTTGGTGGTCTTGCTAAAAGCGGTCCTCTACGACTAAGGTCTAATGATGTGTTCACATTGGATTTAAGTGAAAATAAGCCATGCTGGCGGTGTATCACCGGCAGTGGAATGCCAGGAGCCAGTAATCCAGCTGGAGTTGGTCCACCCCCTCGCCTTGACCATGTCGCTGTGAGCCTTCCTGGAGGGAGAATTTTGATATTTGGTGGATCAGTGGCAGGTCTTCACTCCGCTTCAAAGCTTTACCTGCTGGATCCGACTGAAGAGAAGCCTACCTGGAGGATACTGAATGTTCCTGGCCGCCCTCCGCGATTTGCCTGGGGCCACAGTACCTGTGTTGTGGGAGGTACAAAGGCGATAGTTCTTGGAGGACAAACTGGAGAGGAGTGGACACTAACTGAACTGCATGAGCTTTCTCTGGTAAGCTCTTTAGTCTGA - >LOC_Os02g05700.2
ATGGAGTGGGACAGCGACTCGGAGGGGAGCGGAGACGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGGGGTTGAGGTGGGGGGAGGTGGGGATGGGGGCGTGGGCGTGGGAGTCGGTGGGGGATTCGCGCTGGCGATCGAGGGGGTGCTGGGCGCGTGCGGGCTGGTGGTGTCGGACGCGCTGGAGCCGGATTTCCCCATCATCTACGTCAACCGCGGCTTCGAGGACGCCACCGGGTACCGCGCCGAGGAGGTGCTCGGGAGGAACTGTCGATTCTTGCAGTGTAGAGGACCATTTGCTAAGAGGAGACATCCCCTTGTTGATACTACAGTAGTTACTGACATTCGGAGATGCTTAGAGGAAGGCACTGTGTTCCAGGGCGATCTGCTGAACTTTAGGAAAGATGGTTCTCCATTCATGGCAAAGCTCCAGTTAACACCCATTTATGGAGATGACGAAACAATAACCCACTATATGGGCATGCAGTTCTTCAATGACTCTAATGTTGATTTGGGGCCATTGTCTGTCTCTACAACAAAGGAGATTGTGAGATCTACTTTGATTACACCAGATAACACCATCCGACCAAGTCCAATGGGGAAGGGCTTCTGCTCAGAGCATTCTGATCTTTTCCTATTGAGTGATGAGGTACTTTGCCAGAAGATCCTATCAAGATTATCGCCCAGGGATATAGCATCTGTAAACTCTGTATGTAAACGGCTGTACCACTTAACAAGGAATGACGACCTTTGGAGAATGGTTTGTCAGAATGCATGGGGCAGTGAAGCAACTCAAGTTCTTGAGACTGTGGCTGGAACAAGAAGTTTGGCATGGGGGCGGTTAGCAAGAGAGTTGACCACCCTGGAAGCTGTCACCTGGAGGAAATTGACTGTTGGGGGTGCAGTGGAGCCTTCTCGCTGCAACTTCAGCGCTTGTGCGGCAGGGAACCGTGTTGTCCTTTTTGGAGGGGAAGGTGTTAACATGCAGCCAATGAATGATACATTTGTGCTTGATTTGAATGCCAGCAAGCCAGAATGGAGGCACATCAATGTGAGATCGGCTCCTCCTGGGCGCTGGGGTCATACCCTTTCTTGCCTAAATGGATCACGGTTGGTTTTGTTTGGTGGTTGTGGAAGGCAGGGCCTGCTCAATGATGTGTTCATGTTGGATTTGGATGCACAGCAACCAACTTGGCGTGAGATTCCTGGCCTTGCACCACCAGTTCCACGGTCATGGCATAGTTCTTGCACATTGGATGGAACAAAATTGGTGGTATCTGGTGGCTGTGCTGATTCTGGTGTGCTTCTCAGTGACACGTATCTTTTGGATGTAACAATGGAAAGACCTGTTTGGAGGGAGATACCTGCATCTTGGACTCCACCTTGTAGATTGGGGCACTCGCTCTCTGTCTACGATGGCAGGAAAATCCTGATGTTTGGTGGTCTTGCTAAAAGCGGTCCTCTACGACTAAGGTCTAATGATGTGTTCACATTGGATTTAAGTGAAAATAAGCCATGCTGGCGGTGTATCACCGGCAGTGGAATGCCAGGAGCCAGTAATCCAGCTGGAGTTGGTCCACCCCCTCGCCTTGACCATGTCGCTGTGAGCCTTCCTGGAGGGAGAATTTTGATATTTGGTGGATCAGTGGCAGGTCTTCACTCCGCTTCAAAGCTTTACCTGCTGGATCCGACTGAAGAGAAGCCTACCTGGAGGATACTGAATGTTCCTGGCCGCCCTCCGCGATTTGCCTGGGGCCACAGTACCTGTGTTGTGGGAGGTACAAAGGCGATAGTTCTTGGAGGACAAACTGGAGAGGAGTGGACACTAACTGAACTGCATGAGCTTTCTCTGGTAAGCTCTTTAGTCTGA
Protein Sequence
- >LOC_Os02g05700.1
MEWDSDSEGSGDEEEEEEEEEEEGVEVGGGGDGGVGVGVGGGFALAIEGVLGACGLVVSDALEPDFPIIYVNRGFEDATGYRAEEVLGRNCRFLQCRGPFAKRRHPLVDTTVVTDIRRCLEEGTVFQGDLLNFRKDGSPFMAKLQLTPIYGDDETITHYMGMQFFNDSNVDLGPLSVSTTKEIVRSTLITPDNTIRPSPMGKGFCSEHSDLFLLSDEVLCQKILSRLSPRDIASVNSVCKRLYHLTRNDDLWRMVCQNAWGSEATQVLETVAGTRSLAWGRLARELTTLEAVTWRKLTVGGAVEPSRCNFSACAAGNRVVLFGGEGVNMQPMNDTFVLDLNASKPEWRHINVRSAPPGRWGHTLSCLNGSRLVLFGGCGRQGLLNDVFMLDLDAQQPTWREIPGLAPPVPRSWHSSCTLDGTKLVVSGGCADSGVLLSDTYLLDVTMERPVWREIPASWTPPCRLGHSLSVYDGRKILMFGGLAKSGPLRLRSNDVFTLDLSENKPCWRCITGSGMPGASNPAGVGPPPRLDHVAVSLPGGRILIFGGSVAGLHSASKLYLLDPTEEKPTWRILNVPGRPPRFAWGHSTCVVGGTKAIVLGGQTGEEWTLTELHELSLVSSLV* - >LOC_Os02g05700.2
MEWDSDSEGSGDEEEEEEEEEEEGVEVGGGGDGGVGVGVGGGFALAIEGVLGACGLVVSDALEPDFPIIYVNRGFEDATGYRAEEVLGRNCRFLQCRGPFAKRRHPLVDTTVVTDIRRCLEEGTVFQGDLLNFRKDGSPFMAKLQLTPIYGDDETITHYMGMQFFNDSNVDLGPLSVSTTKEIVRSTLITPDNTIRPSPMGKGFCSEHSDLFLLSDEVLCQKILSRLSPRDIASVNSVCKRLYHLTRNDDLWRMVCQNAWGSEATQVLETVAGTRSLAWGRLARELTTLEAVTWRKLTVGGAVEPSRCNFSACAAGNRVVLFGGEGVNMQPMNDTFVLDLNASKPEWRHINVRSAPPGRWGHTLSCLNGSRLVLFGGCGRQGLLNDVFMLDLDAQQPTWREIPGLAPPVPRSWHSSCTLDGTKLVVSGGCADSGVLLSDTYLLDVTMERPVWREIPASWTPPCRLGHSLSVYDGRKILMFGGLAKSGPLRLRSNDVFTLDLSENKPCWRCITGSGMPGASNPAGVGPPPRLDHVAVSLPGGRILIFGGSVAGLHSASKLYLLDPTEEKPTWRILNVPGRPPRFAWGHSTCVVGGTKAIVLGGQTGEEWTLTELHELSLVSSLV*