Information report for CDKB1;1;CDKB1
Gene Details
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Functional Descriptions
- In plants, the CDKB1;1 transcripts were highly expressed in the shoot and root apical meristems, but not in mature plant organs.
- In Arabidopsis, four A2-type cyclins (CYCA2s) function redundantly in regulating CDKB1 activity to promote the asymmetric division for stomatal initiation and the symmetric division of guard mother cells (GMCs).
- Cross-species complementation tests demonstrated that OsCYCA2;1 and OsCDKB1;1 could complement the defective stomatal phenotypes of Arabidopsis cyca2 and cdkb1 mutants, but also could suppress DNA endoduplication and cell enlargement.
- Additionally, Yeast one-hybrid assay and electrophoretic mobility shift assay (EMSA) showed that OsFLP directly bound to the promoter region of Oryza sativa B-type Cyclin-Dependent Kinase 1;1 (OsCDKB1;1), and the expression of OsCDKB1;1 was repressed in osflp.
- Disturbing the expression of OsCDKB1;1 remarkably enhanced the tolerance to salt stress.
- Taken together, our findings reveal a crucial function of OsFLP regulating OsCDKB1;1 in salt tolerance and largely extend the knowledge about the role of OsFLP in rice.
Functional Keywords
- root-apical-meristem , root , shoot , meristem , stomatal , Kinase , kinase , salt , tolerance , salt-tolerance , salt-stress , stress
Literature and News
- Isolation and characterization of a rice cDNA encoding B1-type cyclin-dependent kinase . DOI: 10.5511/plantbiotechnology.23.211
- Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice . DOI: 10.1093/pcp/pcu154 ; PMID: 25392068
- A2-type cyclin is required for the asymmetric entry division in rice stomatal development . DOI: 10.1093/jxb/ery158 ; PMID: 29701802
- Transcriptomic analysis reveals the role of FOUR LIPS in response to salt stress in rice . DOI: 10.1007/s11103-022-01282-9 ; PMID: 35583702
Gene Resources
- UniProt: Q8L4P8
- EMBL: AB239918, AP003316, AP003349
- AlphaFoldDB: Q8L4P8
- EnsemblPlants: Os01t0897000-01
- Gramene: Os01t0897000-01
- Orthologous matrix: PGTCLRE
- InterPro: IPR000719, IPR008271, IPR011009
- PANTHER: PTHR24056, PTHR24056:SF254
- SUPFAM: SSF56112
- PROSITE: PS00107, PS00108, PS50011
- Gene3D: 1.10.510.10, 3.30.200.20
- OrthoDB: Q8L4P8
- SWISS-MODEL: Q8L4P8
- eggNOG: KOG0594
Sequences
cDNA Sequence
- >LOC_Os01g67160.1
ATGGAGAAGTACGAGAAGCTGGAGAAGGTGGGGGAAGGGACGTACGGGAAGGTGTACAAGGCGCAGGACAGGGCGACGGGGCAGCTGGTGGCGCTGAAGAAGACGAGGCTGGAGATGGACGAGGAGGGGATCCCGCCCACCGCGCTGCGCGAGATCTCCATCCTCAGGCTGCTCTCCCAGTCGCTCTACGTCGTCCGCCTCCTCTCCGTCGAGCAGGCCACCAAGAACGGCAAGCCCGTCCTCTACCTCGTCTTCGAGTTCCTCGACACCGACCTCAAGAAGTTCGTCGACGCCTACCGCAAGGGCCCCAACCCTCGCCCCCTCCCCACCAACGTCATCAAGAGCTTCTTGTATCAGTTATGCAAAGGAGTCGCACATTGCCATGGCCATGGTGTCCTTCACCGTGATTTAAAGCCACAAAACCTGTTGGTCGACAAGGAAAAGGGGATATTGAAAATTGCTGATCTTGGGCTAGGTAGGGCGTTCACTGTTCCTATGAAAAGCTACACACATGAGATTGTGACTCTTTGGTACAGAGCTCCTGAAGTTTTGCTTGGATCAACACATTACTCAACCGGTGTTGACATTTGGTCCGTTGGTTGCATCTTCGCTGAAATGGTCAGAAGACAAGCTCTTTTTCCAGGTGACTCTGAGTTGCAACAGTTGCTTCACATTTTCAGGTTGTTGGGAACTCCTACTGAGGAGCAGTGGCCTGGAGTAACTGATTTGAGGGACTGGCATGAGTTTCCACAGTGGAAGCCACAGATTTTAGAACGTCAAGTCCCATCATTGGAGCCTGAAGGAGTTGACCTTTTATCGAAAATGCTCCAGTATAACCCAGCAAATCGGATCTCAGCAAAGGCTGCTATGGAACACCCCTACTTCGACAGCCTCGACAAGTCCCAGTTCTAGTTTGTACCATGTGATTGACGAAGTCCATGTTCTGTTGTGTCATTTGATTATAAACGTGTTGCTGTTAGCAGCAAGGAAATTCGTTTTGCCTACTTAGCACCCTACTTTGTGATCCAACAAGGAAATCCGTTTGCCATCTAGGCAACTTGAATACAGTTTGAATGTAAAATGGGTTTGTTTCTATGCTGTATGGCATATGTATTATGGACAAGAAGGTTGCAATATATTTGCCTGTTTCTTTG
CDS Sequence
- >LOC_Os01g67160.1
ATGGAGAAGTACGAGAAGCTGGAGAAGGTGGGGGAAGGGACGTACGGGAAGGTGTACAAGGCGCAGGACAGGGCGACGGGGCAGCTGGTGGCGCTGAAGAAGACGAGGCTGGAGATGGACGAGGAGGGGATCCCGCCCACCGCGCTGCGCGAGATCTCCATCCTCAGGCTGCTCTCCCAGTCGCTCTACGTCGTCCGCCTCCTCTCCGTCGAGCAGGCCACCAAGAACGGCAAGCCCGTCCTCTACCTCGTCTTCGAGTTCCTCGACACCGACCTCAAGAAGTTCGTCGACGCCTACCGCAAGGGCCCCAACCCTCGCCCCCTCCCCACCAACGTCATCAAGAGCTTCTTGTATCAGTTATGCAAAGGAGTCGCACATTGCCATGGCCATGGTGTCCTTCACCGTGATTTAAAGCCACAAAACCTGTTGGTCGACAAGGAAAAGGGGATATTGAAAATTGCTGATCTTGGGCTAGGTAGGGCGTTCACTGTTCCTATGAAAAGCTACACACATGAGATTGTGACTCTTTGGTACAGAGCTCCTGAAGTTTTGCTTGGATCAACACATTACTCAACCGGTGTTGACATTTGGTCCGTTGGTTGCATCTTCGCTGAAATGGTCAGAAGACAAGCTCTTTTTCCAGGTGACTCTGAGTTGCAACAGTTGCTTCACATTTTCAGGTTGTTGGGAACTCCTACTGAGGAGCAGTGGCCTGGAGTAACTGATTTGAGGGACTGGCATGAGTTTCCACAGTGGAAGCCACAGATTTTAGAACGTCAAGTCCCATCATTGGAGCCTGAAGGAGTTGACCTTTTATCGAAAATGCTCCAGTATAACCCAGCAAATCGGATCTCAGCAAAGGCTGCTATGGAACACCCCTACTTCGACAGCCTCGACAAGTCCCAGTTCTAG
Protein Sequence
- >LOC_Os01g67160.1
MEKYEKLEKVGEGTYGKVYKAQDRATGQLVALKKTRLEMDEEGIPPTALREISILRLLSQSLYVVRLLSVEQATKNGKPVLYLVFEFLDTDLKKFVDAYRKGPNPRPLPTNVIKSFLYQLCKGVAHCHGHGVLHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPMKSYTHEIVTLWYRAPEVLLGSTHYSTGVDIWSVGCIFAEMVRRQALFPGDSELQQLLHIFRLLGTPTEEQWPGVTDLRDWHEFPQWKPQILERQVPSLEPEGVDLLSKMLQYNPANRISAKAAMEHPYFDSLDKSQF*