Gene Details:
- MSU gene ID: LOC_Os01g62860
- RAPdb gene ID: Os01g0847600
- Gene Symbol: OsAKR1 OsI_04426
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Heterologous synthesis of the OsAKR1 enzyme in transgenic tobacco plants resulted in increased tolerance against oxidative stress generated by methylviologen (MV) and improved resistance to high temperature.
- The OsAKR1 recombinant protein exhibited a high nicotinamide adenine dinucleotide phosphate-dependent catalytic activity to reduce toxic aldehydes including glycolysis-derived methylglyoxal (MG) and lipid peroxidation-originated malondialdehyde (MDA).
- These results support the positive role of OsAKR1 in abiotic stress-related reactive aldehyde detoxification pathways and its use for improvement of stress tolerance in plants.
Function-related keywords:
Literature:
- Cloning and characterization of AKR4C14, a rice aldo-keto reductase, from Thai Jasmine rice . DOI: 10.1007/s10930-011-9371-8 ; PMID: 22101802
- Overproduction of a rice aldo-keto reductase increases oxidative and heat stress tolerance by malondialdehyde and methylglyoxal detoxification . DOI: 10.1007/s11103-011-9735-7 ; PMID: 21246257
- Aldo-keto reductase enzymes detoxify glyphosate and improve herbicide resistance in plants . DOI: 10.1111/pbi.12632 ; PMID: 27611904
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os01g62860.1
TCCCGTAGTCTCGTGGCCGCGCCGGACTGCCGGGACAACCTAGCCGAGCGCTCCCGCTGGCCGCTGCCTACAGTAAAGCAGCGCGCTGCGCCCGCCTCGCCGCCGCCTCCGCAGGGTCCCCGTGCCTTCTCGCACCGGCGGCACCGCTCGATCTCTGCGTGACGGCGTGTGAGGCTGTGGGGTGGTAGTAGGGGCGGGCGGAGATGGCGAAGCATTTCGTGCTCAACACCGGCGCCAAGATCCCCTCGGTGGGGCTCGGCACCTGGCAGTCCGACCCGGGCGTCGTCGGCGACGCCGTCTACGCCGCTGTCAAGGCGGGGTACCGGCACATCGATTGCGCCAGAATGTACAAAAATGAAAATGAGGTGGGGATAGCTCTGAAGAAGCTATTTGAAGAAGGTGTTGTCAAGCGTGAAGATTTATTTATCACATCTAAGCTATGGTGTGATTGTCATGCCCCAGAGGATGTGCCTGAGTCACTAGACAAAACTCTGAGTGACTTACAGCTTGAGTACCTGGATCTTTACCTTATTCATTGGCCATTCAGAGTCAAGAAGGGCTCAGGCATTAGTAACACTGAAGACTACATACCACCTGACATCCCATCTACCTGGGGAGCAATGGAGAAGCTATATGATTCTGGTAAATCTCGTGCCATTGGTGTAAGTAACTTCTCATCAAAAAAACTGGGTGACCTGCTTGCTGTAGCCTGTGTACCTCCAGCTGTTGATCAGGTAGAATGCCATCCTGGTTGGCAGCAAACGAAGCTACATAACTTCTGCCAGTCAACTGGCGTTCATCTTTCTGCATACTCGCCTCTAGGTTCACCTGGTTCAACATGGATGAACAGTAACGTCCTTAAGGAATCCGTCATCATCTCAATTGCAGAGAAGCTCGGCAAAACTCCTGCACAAGTGGCACTGCACTGGAACATTCAGATGGGTCACAGTGTACTCCCAAAAAGTGTGACCGAAGAAAGGATAAAGCAGAACATAGATGTTTATGACTGGTCTATTCCAGAGGACTTGCTTGTTAAGTTCTCTGAGATTAAGCAGGTTAGGCTTCTCAGGGGCGACGTCATTGTTAATCCCCACAGCGTTTATAAGACCCATGAGGAGCTCTGGGACGGCGAAATTTAGATGCAGTCAGCTTACGTTAGTGCCAGTCACTCTCACTGAACATTATTTTTTCACGAATTTACGCTTATCTAATGTATGGTGTTTGAGTCTCTTGAGCTCCTATTCAATGTAATGAACCTGCTTGATCAGCAGCATCATGTTCCCTTAGAATTCGTATTAGCGCTCCTCTGAATAATACTGGATCATGTCATTTGTATGCTTCGCCTCTGGCATCATTTATCCCATGCTACTTGTTTGTCTA
CDS Sequence
- >LOC_Os01g62860.1
ATGGCGAAGCATTTCGTGCTCAACACCGGCGCCAAGATCCCCTCGGTGGGGCTCGGCACCTGGCAGTCCGACCCGGGCGTCGTCGGCGACGCCGTCTACGCCGCTGTCAAGGCGGGGTACCGGCACATCGATTGCGCCAGAATGTACAAAAATGAAAATGAGGTGGGGATAGCTCTGAAGAAGCTATTTGAAGAAGGTGTTGTCAAGCGTGAAGATTTATTTATCACATCTAAGCTATGGTGTGATTGTCATGCCCCAGAGGATGTGCCTGAGTCACTAGACAAAACTCTGAGTGACTTACAGCTTGAGTACCTGGATCTTTACCTTATTCATTGGCCATTCAGAGTCAAGAAGGGCTCAGGCATTAGTAACACTGAAGACTACATACCACCTGACATCCCATCTACCTGGGGAGCAATGGAGAAGCTATATGATTCTGGTAAATCTCGTGCCATTGGTGTAAGTAACTTCTCATCAAAAAAACTGGGTGACCTGCTTGCTGTAGCCTGTGTACCTCCAGCTGTTGATCAGGTAGAATGCCATCCTGGTTGGCAGCAAACGAAGCTACATAACTTCTGCCAGTCAACTGGCGTTCATCTTTCTGCATACTCGCCTCTAGGTTCACCTGGTTCAACATGGATGAACAGTAACGTCCTTAAGGAATCCGTCATCATCTCAATTGCAGAGAAGCTCGGCAAAACTCCTGCACAAGTGGCACTGCACTGGAACATTCAGATGGGTCACAGTGTACTCCCAAAAAGTGTGACCGAAGAAAGGATAAAGCAGAACATAGATGTTTATGACTGGTCTATTCCAGAGGACTTGCTTGTTAAGTTCTCTGAGATTAAGCAGGTTAGGCTTCTCAGGGGCGACGTCATTGTTAATCCCCACAGCGTTTATAAGACCCATGAGGAGCTCTGGGACGGCGAAATTTAG
Protein Sequence
- >LOC_Os01g62860.1
MAKHFVLNTGAKIPSVGLGTWQSDPGVVGDAVYAAVKAGYRHIDCARMYKNENEVGIALKKLFEEGVVKREDLFITSKLWCDCHAPEDVPESLDKTLSDLQLEYLDLYLIHWPFRVKKGSGISNTEDYIPPDIPSTWGAMEKLYDSGKSRAIGVSNFSSKKLGDLLAVACVPPAVDQVECHPGWQQTKLHNFCQSTGVHLSAYSPLGSPGSTWMNSNVLKESVIISIAEKLGKTPAQVALHWNIQMGHSVLPKSVTEERIKQNIDVYDWSIPEDLLVKFSEIKQVRLLRGDVIVNPHSVYKTHEELWDGEI*