Gene Details:
- MSU gene ID: LOC_Os01g57610
- RAPdb gene ID: Os01g0785400
- Gene Symbol: OsGH3.1 OsGH3-1 LC1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Constitutive expression of OsGH3.1 reduces auxin content and enhances defense response and resistance to a fungal pathogen in rice.
- LC1 is transcribed in various tissues and encodes OsGH3.1, an indole-3-acetic acid (IAA) amido synthetase, whose homolog of Arabidopsis functions in maintaining the auxin homeostasis by conjugating excess IAA to various amino acids.
- Phenotypic analysis confirmed the exaggerated leaf angles of LC1-D due to the stimulated cell elongation at the lamina joint.
- The transcript abundance of nearly all OsGH3 genes is enhanced on auxin treatment, with the effect more pronounced on OsGH3.1, -2, and -4.
- Indeed, recombinant LC1 can catalyze the conjugation of IAA to Ala, Asp, and Asn in vitro, which is consistent with the decreased free IAA amount in LC1-D mutant.
- LC1-D is insensitive to IAA and hypersensitive to exogenous BR, in agreement with the microarray analysis that reveals the altered transcriptions of genes involved in auxin signaling and BR biosynthesis.
- Studies on the rice LEAF INCLINATION1 (LC1), an IAA-amido synthetase, reveal the effects of auxin in leaf inclination control.
- Through genetic screening, a rice gain-of-function mutant leaf inclination1, LC1-D, was identified from the Shanghai T-DNA Insertion Population (SHIP).
Function-related keywords:
- defense-response , iaa , lamina , auxin , homeostasis , cell-elongation , BR , defense , leaf
Literature:
- The auxin-responsive GH3 gene family in rice (Oryza sativa) . DOI: 10.1007/s10142-005-0142-5 ; PMID: 15856348
- Studies on the rice LEAF INCLINATION1 (LC1), an IAA-amido synthetase, reveal the effects of auxin in leaf inclination control . DOI: 10.1093/mp/sss064 ; PMID: 22888153
- Constitutive expression of OsGH3.1 reduces auxin content and enhances defense response and resistance to a fungal pathogen in rice . DOI: 10.1094/MPMI-22-2-0201 ; PMID: 19132872
Related News:
Gene Resources:
- NCBI ID: AK063368
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os01g57610.1
CACAAACCAAGCTCCATACCGCTGCCTACATCTCTGGTTAGTAGCCACCAAGGTCCAAGGAGTAACACGCTCCGTGAGAGACCGAAATCCAGGGAGCACAAATTGCACATTTGCACCAAGCACACTCGCTGCAGCTGCAGTGACATGCCGGAAGCACCGACCGCCAAGACAGCACCGGCCTACGGCTACGCCCCCGGGGCGCACGCCGAGGCGCTCGAGTTCATCGAGCACGTCACGGCGAACGCCGGGCAGGTGCAGCGGCGCGTGCTCGGCGAGATCCTGGCGCAGAACGCGCCGGCCGAGTACCTGCGCCGGTACGGAATCCCCGGGTCCCCCGACGTTGTCGACGCCTTCCGCCGCCTCGTCCCGCTCGTCACATACGAGGGCCTCCAGCCAGACATCCTCCGCATCGCCAACGGCGACACCTCGCCGATCTTCTCCGGGAAGCCTATCTCCGAATTCCTCACGAGCTCGGGCACGTCGGGAGGGGAGAGGAAGCTCATGCCGACCATCGCCGACGAGATGAACAGGCGGTCGCTGCTGTACAGCCTGCTGATGCCGGTGATGAGCCAGTCGGTGTCCGGGCTCGACAAAGGCAAGGCGATGTACCTGCTCTTCGTGAAGGCGGAGTCGCGCACGCCGGGCGGGCTCGCGGCGCGGCCGGTGCTCACAAGCTACTACCGGAGCCGGCAGTTCCTCGACCGTCCGCGCGACCCCTACACATCTTACACGAGCCCCGACGAGGCCATCCTGTGCGTGGACTCCTACCAGAGCATGTACGCGCAGCTGCTCTGCGGCCTCGTCCACCGCGCCGACGTGCTGCGCGTGGGCGCCGTGTTCGCCTCCGGCTTCCTCCGCGCCATCCATTTCCTCGAGAAGCACTGGGCGCGCCTCTGCCACGACATCCGCACCGGCGAGCTCGACCCGGAGATCACCGACCGCGTGGTGCGCGACGCCGTCGGGCGGGTGCTCCGCGCCGACCCGGCGCTCGCCGACGCGATCGAGGACGAGTGCGCTAGGGCGTCGTGGGAGGGCATCATCCGGCGCCTGTGGCCACGCACCAAGTACATCGACGTGATCGTGACCGGCACCATGTCGCAGTACATCCCGACGCTCGAGTTCTACGGCGGCGGCCTGCCGCTGACGTGCACCATGTACGCCTCTTCGGAGTGCTACTTCGGCCTCAACCTGAATCCCATGTGCAAGCCCAGCGACGTCGCCTACACGCTCATCCCCACCATGTGCTACTACGAGTTCCTCCCCGTCAATTGCAACAATGCCACTGCCGAGGCGAGCCACCGCGACCTCGTCGACCTGGTCGACGTAAAGCTCGGGCACGAGTACGAGCTCGTGGTCACCACGTATTCCGGGTTGTATCGTTATCGCGTGGGCGACGTGCTGAGGGTGGCGGGGTTCAAGAACAAGGCCCCGATGTTCAGCTTCGTGCGGCGGCAGAACGTGGCGCTGAGCGTCGACTCGGACAAGACGGACGAGACGGAGCTGCACGCGGCGGTGAGCGGCGCGGTGCAGCACCTGGCGCCGTTCGGCGCGTCGCTGGTGGAGTACACGAGCTACGCGGACGCGGCCACCATCCCGGGCCACTACGTGCTGTTCTGGGAGCTGCGCGCCGGCAGCACGGCGGTGCCGGCGTCCGTGTTCGAGGAGTGCTGCCTGTCCGTGGAGGAGGCACTGAACAGCGTCTACCGGCAGGGCCGCGCGTGCGACAGGTCCATCGGCCCGCTCGAGATACGCGTCGTGGCGGAGGGCACCTTCGACAAGCTCATGGACTACGCGATCAGCCGGGGCGCGTCCATCAACCAGTACAAGGCGCCGCGGTGCGTGCGCCCTGGCCCGGTCGTCGAGCTGCTCGACGCGAGGGTGCAGGGCAAGTACTTCAGTCCCAAGTGCCCCAAGTGGAGCCCCGGGAACAAGCAATGGAACAAAAGCAAGGATCTGGTCGGCAAGGGAGACGCCTAATATTGAAGCTAGAGGGTGATGATCTGATCGAGTATTTGTGTGAGCTGGTAATTAATTAACGGTACATGCATATGGTCATTGGTCGATATGTTTCTTTAGGGATATGATAATTCATGTTTGAATTATCTCTGATGCTGCGAGAGGATCGAATAGTTATGAGATGACGACTTAGCCTATATGATCATTTGCTTTACTCTTTCTCTGCTGTAACGCAGTATATGTTATTTCCTCCGTCTCAAAATATAAGCATTTTTAGTACATTGATAAATTAAACATTTTTAAATTTGACTATTAATAGCAAGAAAAATAAAAAATCAATCATGTAAAATTGATATTCCTAGATTTATCATTAAAAACACTATCATAATATGCAACTTTTTTTATTTAAAATATTTTATTTTTATATATATTGTTGGTTAAAGTAGCATCTTGGATATCGTGTCAGGGTTTAAAATGATTATATTTTAGGACGGAGGGAGTAATTAGTAGCCGTATTGAATAGACTTTTCTACTCAAAGATATGTCTCTCAAATTTATGCACATCGCACGGTGTGCATGCAGTGCCGAGAATTTATTACTTGTCAAAATTGTTGGACTACTGCTACTGATGATAAATAACTTGTCAAAATGATAAACTACATCAAATACTACTATAGTAGTATATTATAATCTTCCTTTATACTAGTATATGCTATCTCATGATGGTTGACATTAA
CDS Sequence
- >LOC_Os01g57610.1
ATGCCGGAAGCACCGACCGCCAAGACAGCACCGGCCTACGGCTACGCCCCCGGGGCGCACGCCGAGGCGCTCGAGTTCATCGAGCACGTCACGGCGAACGCCGGGCAGGTGCAGCGGCGCGTGCTCGGCGAGATCCTGGCGCAGAACGCGCCGGCCGAGTACCTGCGCCGGTACGGAATCCCCGGGTCCCCCGACGTTGTCGACGCCTTCCGCCGCCTCGTCCCGCTCGTCACATACGAGGGCCTCCAGCCAGACATCCTCCGCATCGCCAACGGCGACACCTCGCCGATCTTCTCCGGGAAGCCTATCTCCGAATTCCTCACGAGCTCGGGCACGTCGGGAGGGGAGAGGAAGCTCATGCCGACCATCGCCGACGAGATGAACAGGCGGTCGCTGCTGTACAGCCTGCTGATGCCGGTGATGAGCCAGTCGGTGTCCGGGCTCGACAAAGGCAAGGCGATGTACCTGCTCTTCGTGAAGGCGGAGTCGCGCACGCCGGGCGGGCTCGCGGCGCGGCCGGTGCTCACAAGCTACTACCGGAGCCGGCAGTTCCTCGACCGTCCGCGCGACCCCTACACATCTTACACGAGCCCCGACGAGGCCATCCTGTGCGTGGACTCCTACCAGAGCATGTACGCGCAGCTGCTCTGCGGCCTCGTCCACCGCGCCGACGTGCTGCGCGTGGGCGCCGTGTTCGCCTCCGGCTTCCTCCGCGCCATCCATTTCCTCGAGAAGCACTGGGCGCGCCTCTGCCACGACATCCGCACCGGCGAGCTCGACCCGGAGATCACCGACCGCGTGGTGCGCGACGCCGTCGGGCGGGTGCTCCGCGCCGACCCGGCGCTCGCCGACGCGATCGAGGACGAGTGCGCTAGGGCGTCGTGGGAGGGCATCATCCGGCGCCTGTGGCCACGCACCAAGTACATCGACGTGATCGTGACCGGCACCATGTCGCAGTACATCCCGACGCTCGAGTTCTACGGCGGCGGCCTGCCGCTGACGTGCACCATGTACGCCTCTTCGGAGTGCTACTTCGGCCTCAACCTGAATCCCATGTGCAAGCCCAGCGACGTCGCCTACACGCTCATCCCCACCATGTGCTACTACGAGTTCCTCCCCGTCAATTGCAACAATGCCACTGCCGAGGCGAGCCACCGCGACCTCGTCGACCTGGTCGACGTAAAGCTCGGGCACGAGTACGAGCTCGTGGTCACCACGTATTCCGGGTTGTATCGTTATCGCGTGGGCGACGTGCTGAGGGTGGCGGGGTTCAAGAACAAGGCCCCGATGTTCAGCTTCGTGCGGCGGCAGAACGTGGCGCTGAGCGTCGACTCGGACAAGACGGACGAGACGGAGCTGCACGCGGCGGTGAGCGGCGCGGTGCAGCACCTGGCGCCGTTCGGCGCGTCGCTGGTGGAGTACACGAGCTACGCGGACGCGGCCACCATCCCGGGCCACTACGTGCTGTTCTGGGAGCTGCGCGCCGGCAGCACGGCGGTGCCGGCGTCCGTGTTCGAGGAGTGCTGCCTGTCCGTGGAGGAGGCACTGAACAGCGTCTACCGGCAGGGCCGCGCGTGCGACAGGTCCATCGGCCCGCTCGAGATACGCGTCGTGGCGGAGGGCACCTTCGACAAGCTCATGGACTACGCGATCAGCCGGGGCGCGTCCATCAACCAGTACAAGGCGCCGCGGTGCGTGCGCCCTGGCCCGGTCGTCGAGCTGCTCGACGCGAGGGTGCAGGGCAAGTACTTCAGTCCCAAGTGCCCCAAGTGGAGCCCCGGGAACAAGCAATGGAACAAAAGCAAGGATCTGGTCGGCAAGGGAGACGCCTAA
Protein Sequence
- >LOC_Os01g57610.1
MPEAPTAKTAPAYGYAPGAHAEALEFIEHVTANAGQVQRRVLGEILAQNAPAEYLRRYGIPGSPDVVDAFRRLVPLVTYEGLQPDILRIANGDTSPIFSGKPISEFLTSSGTSGGERKLMPTIADEMNRRSLLYSLLMPVMSQSVSGLDKGKAMYLLFVKAESRTPGGLAARPVLTSYYRSRQFLDRPRDPYTSYTSPDEAILCVDSYQSMYAQLLCGLVHRADVLRVGAVFASGFLRAIHFLEKHWARLCHDIRTGELDPEITDRVVRDAVGRVLRADPALADAIEDECARASWEGIIRRLWPRTKYIDVIVTGTMSQYIPTLEFYGGGLPLTCTMYASSECYFGLNLNPMCKPSDVAYTLIPTMCYYEFLPVNCNNATAEASHRDLVDLVDVKLGHEYELVVTTYSGLYRYRVGDVLRVAGFKNKAPMFSFVRRQNVALSVDSDKTDETELHAAVSGAVQHLAPFGASLVEYTSYADAATIPGHYVLFWELRAGSTAVPASVFEECCLSVEEALNSVYRQGRACDRSIGPLEIRVVAEGTFDKLMDYAISRGASINQYKAPRCVRPGPVVELLDARVQGKYFSPKCPKWSPGNKQWNKSKDLVGKGDA*