Gene Details:

• MSU gene ID: LOC_Os01g49290
• RAPdb gene ID: Os01g0686800
• Gene Symbol: OsRACK1A
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• OsRACK1A was found to follow a rhythmic expression profile under circadian conditions at both the transcription and the translation levels, although the expression was arrhythmic under salt stress.
• Analysis of plant survival rates, fresh weight, proline content, malondialdehyde, and chlorophyll showed that suppression of OsRACK1A enhanced tolerance to salt stress.
• We identified putative interactors of OsRACK1A, and found that OsRACK1A interacted with many salt stress-responsive proteins directly.
• These results suggest that OsRACK1A is regulated by circadian rhythm, and involved in the regulation of salt stress responses.
• Although the analysis of natural variation revealed no OsRACK1A variants that could avoid being targeted by UvCBP1, expression levels of OsRACK1A are correlated with field resistance against U.
• Overproduction of OsRACK1A restores the OsRACK1A-OsRBOHB association and promotes OsRBOHB phosphorylation to enhance ROS production, conferring rice floral resistance to U.
• Mechanistically, UvCBP1 interacts with the rice scaffold protein OsRACK1A and competes its interaction with the reduced nicotinamide adenine dinucleotide phosphate oxidase OsRBOHB, leading to inhibition of reactive oxygen species (ROS) production.

Function-related keywords:

• salt ,  tolerance ,  salt-stress ,  stress ,  stress-response ,  resistance ,  floral ,  reactive-oxygen-species ,  phosphate

Literature:

• Proteome analysis of detergent-resistant membranes (DRMs) associated with OsRac1-mediated innate immunity in rice .  DOI:  10.1093/pcp/pcp077 ;  PMID:  19502382
• RACK1 functions in rice innate immunity by interacting with the Rac1 immune complex .  DOI:  10.1105/tpc.107.054395 ;  PMID:  18723578
• OsRap2.6 transcription factor contributes to rice innate immunity through its interaction with Receptor for Activated Kinase-C 1 (RACK1) .  DOI:  10.1186/1939-8433-5-35 ;  PMID:  24280008
• CONSTANS-Like 9 (OsCOL9) Interacts with Receptor for Activated C-Kinase 1(OsRACK1) to Regulate Blast Resistance through Salicylic Acid and Ethylene Signaling Pathways .  DOI:  10.1371/journal.pone.0166249 ;  PMID:  27829023
• OsRACK1A, encodes a circadian clock-regulated WD40 protein, negatively affect salt tolerance in rice .  DOI:  10.1186/s12284-018-0232-3 ;  PMID:  30073557
• Overproduction of OsRACK1A, an effector-targeted scaffold protein promoting OsRBOHB-mediated ROS production, confers rice floral resistance to false smut disease without yield penalty .  DOI:  10.1016/j.molp.2022.10.009 ;  PMID:  36245122

Related News:

Gene Resources:

• NCBI ID: D38231
• UniProt accessions:

Sequences: