Gene Details:

• MSU gene ID: LOC_Os01g23620
• RAPdb gene ID: Os01g0338000
• Gene Symbol: OsSar1a
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• However, simultaneous knockdown of OsSar1a/b/c resulted in floury and shrunken seeds, with an increased level of glutelin precursor and decreased level of the mature alpha- and beta-subunit.
• To reveal the route by which glutelin and alpha-globulin exit the ER, four putative Sar1 genes (OsSar1a/b/c/d) were cloned from rice, and transgenic rice were generated with Sar1 overexpressed or suppressed by RNA interference (RNAi) specifically in the endosperm under the control of the rice glutelin promoter.
• OsSar1abc RNAi endosperm generated numerous, spherical, novel protein bodies with highly electron-dense matrixes containing both glutelin and alpha-globulin.
• These results indicated that OsSar1a/b/c play a crucial role in storage proteins exiting from the ER, with functional redundancy in rice endosperm, and glutelin and alpha-globulin transported together from the ER to the Golgi apparatus by a pathway mediated by coat protein complex II.

Function-related keywords:

• seed ,  endosperm

Literature:

• Small GTPase Sar1 is crucial for proglutelin and α-globulin export from the endoplasmic reticulum in rice endosperm .  DOI:  10.1093/jxb/ert128 ;  PMID:  23682119
• A deleterious Sar1c variant in rice inhibits export of seed storage proteins from the endoplasmic reticulum .  DOI:  10.1007/s11103-022-01327-z ;  PMID:  36469200

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: