Gene Details:

• MSU gene ID: LOC_Os01g09100
• RAPdb gene ID: Os01g0186000
• Gene Symbol: OsWRKY10
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Assays of disease in OsWRKY10KD and OsWRKY88KD lines following infection with an incompatible Xoo race, which induced Xa1-mediated resistance in wild-type plants, showed that OsWRKY10 and OsWRKY88 were positive regulators of Xa1-mediated resistance.
• Two transcriptional regulatory cascades of OsWRKY10 were identified in basal defense and Xa1-mediated resistance.
• These OsWRKY10 transcriptional regulatory cascades played important roles in basal defense and Xa1-mediated resistance to enable the mounting of a rapid immune response against pathogens.
• OsWRKY10 also acted as a positive regulator in basal defense by directly or indirectly activating transcription of defense-related genes.
• In the first transcriptional regulatory cascade, OsWRKY47 acted downstream of OsWRKY10 whereas OsWRKY51 acted upstream.
• The transcription factor OsWRKY10 inhibits phosphate uptake via suppressing OsPHT1;2 expression under phosphate-replete condition in rice.
• Here, we functionally characterized a transcription factor in rice (Oryza sativa), OsWRKY10.
• In accordance with this phenotype, OsWRKY10 was transcriptionally induced by Pi, and a subset of Phosphate Transporter 1 (PHT1) genes were up-regulated upon its mutation, suggesting that OsWRKY10 is a transcriptional repressor in Pi uptake.
• Moreover, rice plants expressing the OsWRKY10-VP16 fusion protein (a dominant transcriptional activator) accumulated even more Pi than OsWRKY10.
• Knockout of OsWRKY10 led to increased Pi uptake and accumulation under Pi-replete condition.
• Genetic analysis showed that OsPHT1;2 was responsible for the increased Pi accumulation in OsWRKY10.
• Furthermore, during Pi starvation, OsWRKY10 protein was degraded through the 26S proteasome.

Function-related keywords:

• resistance ,  disease ,  defense ,  immune-response ,  xoo ,  transcriptional-regulator ,  transcription-factor ,  transporter ,  phosphate ,  transcriptional-activator ,  Pi ,  pi ,  Pi-uptake ,  phosphate-transport ,  transcriptional-repressor

Literature:

• WRKY10 transcriptional regulatory cascades in rice are involved in basal defense and Xa1-mediated resistance .  DOI:  10.1093/jxb/eraa135 ;  PMID:  32227093
• The transcription factor OsWRKY10 inhibits phosphate uptake via suppressing OsPHT1;2 expression under phosphate-replete conditions in rice .  DOI:  10.1093/jxb/erac456 ;  PMID:  36402551

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: