Gene Details:
- Gene ID:
- Gene Symbol: MdSOS2L1
- Gene Name:
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- MdSOS2L1 was found to be involved in the regulation of malate excretion, and to inhibit cadmium uptake into roots.
- Using the DUAL membrane system in a screen of an apple cDNA library with MdSOS2L1 as bait, a malate transporter, MdALMT14, was identified as an interactor.
- MdSOS2L1 was also shown to enhance cadmium tolerance in an MdALMT14-dependent manner.
- Transgenic analyses showed that MdSOS2L1 is required for cadmium-induced phosphorylation at the Ser358 site of MdALMT14, a modification that enhanced the stability of the MdALMT14 protein. MdSOS2L1 was also shown to enhance cadmium tolerance in an MdALMT14-dependent manner.
- MdSOS2L1 overexpressing plants showed improved Cd tolerance and increased malate accumulation/excretion.
Function-related keywords:
Literature:
- Phosphorylation of a malate transporter promotes malate excretion and reduces cadmium uptake in apple. DOI: 10.1093/jxb/eraa121 ; PMID: 32147696
Related News:
Gene Resources:
Sequences:
cDNA Sequence
CDS Sequence
Protein Sequence