Gene Details:

• Gene ID:
• Gene Symbol: MdSE
• Gene Name: SERRATE
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• MdSE acts as a negative regulator of apple (Malus × domestica) drought resistance by regulating the expression levels of MdMYB88 and MdMYB124 and miRNAs, including mdm-miR156, mdm-miR166, mdm-miR172, mdm-miR319, and mdm-miR399.
• MdSE interacts with MdMYB88 and MdMYB124, two positive regulators of apple drought resistance. MdSE decreases the transcript and protein levels of MdMYB88 and MdMYB124, which directly regulate the expression of MdNCED3, a key enzyme in abscisic acid (ABA) biosynthesis.
• MdSE RNAi transgenic plants are more sensitive to ABA-induced stomatal closure, whereas MdSE OE plants are less sensitive.
• Taken together, by revealing the negative role of MdSE, our results broaden our understanding of the apple drought response and provide a candidate gene for apple drought improvement through molecular breeding.

Function-related keywords:

• resistance ,  drought ,  aba ,  breeding ,  stomatal ,  abscisic-acid ,  aba-biosynthesis ,  drought-resistance ,  abscisic-acid-biosynthesis ,  drought-response ,  protein

Literature:

• Apple SERRATE negatively mediates drought resistance by regulating MdMYB88 and MdMYB124 and microRNA biogenesis.   DOI:  10.1038/s41438-020-0320-6 ;  PMID:  32637126

Related News:

Gene Resources:

• NCBI ID: KY568649
• UniProt accessions:

Orthologs:

Sequences: