Gene Details:
- Gene ID: MDP0000886637
- Gene Symbol: MdARF1
- Gene Name: ARF domain class transcription factor 1
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- The miR7125-MdARF1 module enhances the resistance of apple to Colletotrichum gloeosporioides by promoting lignin synthesis in response to salicylic acid signalling.
- MdARF1, a transcription factor upstream of MdMYB46, via yeast library screening and determined that MdARF1 was regulated by miR7125 through psRNATarget prediction.
- This regulatory relationship was confirmed through LUC and qRT-PCR experiments, demonstrating that miR7125 negatively regulates MdARF1.
- Overexpression of the MdARF1 enhanced the disease resistance of apples to C. gloeosporioides.
- These results suggest that MdARF1 is a transcriptional activator localized in the nucleus.
Function-related keywords:
- transcription-factor , resistance , disease , disease-resistance , nucleus , salicylic-acid , lignin , transcriptional-activator , transcription-activator
Literature:
- The miR7125-MdARF1 module enhances the resistance of apple to Colletotrichum gloeosporioides by promoting lignin synthesis in response to salicylic acid signalling. DOI: 10.1111/pbi.14401 ; PMID: 38852059
Related News:
Gene Resources:
- NCBI ID: HM122436.1
- UniProt accessions: D9ZIM2
Orthologs:
Sequences:
cDNA Sequence
CDS Sequence
- >MDP0000886637
ATGCAAATATTGGATGATCTGTTAATTTTCAGATATCCCGGAGAACAAAAGAGAATTAATTCGGAGTTATGGCATGCTTGTGCTGGGCCATTGGTTTCTTTGCCTCCGGTTGGAAGTCTTGTGGTGTACTTCCCACAAGGCCACAGCGAGCAAGTTGCAGCATCGATGCAAAAGGAGACTGATTTAATACCGAACTACACCAATCTTCCGTCTAAATTGATATGCATGCTTCACAATGTCACATTGCATGCTGATACCGAAACAGATGAGGTCTACGCACAAATGACTCTCCAACCAGTAAACAAATATGAGAAGGAAGCATTGCTGGCATCTGACATGGGCCTCAAACAAAGTAGGCAACCTGCTGAGTTTTTCTGCAAAACTCTTACAGCTAGCGACACGAGCACTCATGGTGGATTTTCTGTACCTCGTAGAGCAGCTGAGAAGATCCTCCCACCTCTAGATTTTTCTATGCAACCACCTGCTCAGGAGCTTGTTGCAAAAGATTTGCATGATAGTGCGTGGACATTCAGACATATCTATCGAGGCCAACCAAAACGGCACCTGCTGACTACGGGTTGGAGTGTTTTTGTTAGCAACAAAAGACTCTTTGCTGGAGATTCTGTTCTTTTTATAAGGGATGAAAAATCTCAGCTTCTCTTGGGTATAAGGCGTGCTCATAGACAGCAGCCAGCTCTCTCTTCATCAGTCATTTCCAGTGATAGCATGCATATCGGCATTCTTGCGGCTGCAGCTCATGCTGCTGCAAATAACAGTCCATTTACCATATTTTACAACCCAAGGGCAAGCCCTTCTGAATTTGTAGTACCTCTAGCCAAGTACAATAAAGCGATGTATACCCAAGTTTCACTTGGCATGCGATTCAGAATGATGTTTGAGACTGAGGAGTCAGGAGTACGCAGATACATGGGCACAGTCACTGGCATCAGCGATTTGGATCCTGTTAGATGGAAAGGTTCCCAGTGGCGCAATCTTCAGGTTGGATGGGATGAATCAACAGCTGGTGACCGGCCTAGCCGAGTTTCAATTTGGGAAATTGAGCCTGTTATAACTCCTTTCTACATATGCCCTCCTCCATTTTTCAGACCCAAGTTTCCCAAGCAACCAGGGATGCCAGATGATGAATCCGACATCGATAATGCTTTCAGGAGAGCCATGCCTTGGCTTGGAGATGAATTTGGCATGAAGAACTCGCCAAGCTCGTTTTTCCCTGGTTTGAGTTTGGTGCAGTGGATGAACATGCAACAAAATAATCAGTTTTCAGCTGCTCAGTCTGGATTTTTCCCATCCATGGTCCCTCCAACCGGCCTGCAAAATAACCTTGGTACTGATGATCCATCCAAGTTATTGAGTTTTCAAGCCCCGGTGCTGTCTTCGCTCGGTCTCCAGTCAAATAAATCAGCTCCACAAAACCATGCTAGTCAAATGCAGCAGCCGAATGTGACATGGGCTCAACAGCAGCAGCTGCAGCAGTTGATGCATAATCCTATGAACCAACAACAGCAAAGTAACCCCCAACAGCAGCAGCTGCAGCAATTATTGAATTCTTCGGTGAACCAACATCAGCAAAATCACCCCCCGCAGCAGCAGCTGCAGCAATTACTGAATTCTTCGGCAAACCAACATCAGCAAAATCACCCCCAGCAGCAGCAGCAATTATTGCAGACTCCAACGAACCAACAGCTCCATAATTTCTCCCATCAGCAGCAGCAGCGGGAGCCCCAACAACAGCAAGAGCYGCAAAACTTGTTGCAGCATCAGCAGCTGCATCAACAGCAACCACAACGGCACCAGCAACAACAATTATCTCAACCGAATCCGGTAAATAATGGTTCTGTTGCTCCTAACCAGGTCCCGGGCCAAAATTCACAACAACCAGTTATGTTCTCCCAACATCAACAGCAGCAATTACTAACAGGGAATACCCAGCAAGCTGTCCCTTCTTCTAGTAAGAATTCATTTCAGTTGCCAACTGGACAACAAAATTCACAGCTCCAGCAGCAGCAACTAGAACCGCAACCAAGCCTCTTACAAAGGCAGCAGCAGGCAGCACAATTGCAATCACCCCCACATCAATTGTTGCAACAGAGTGTGTCACAGAAAGTACAGCAGCAGCCACAAGTACAGCAATCATCTCCGCAGGGCATCTCTGAGCAACAACTCCAATTACAGTTGCTGCAGAAGTTTCAGCAACAGCAGCAGCCACAATTACTCTCCTCGTCAAGCTCACTTTTGCAGCCTCAACTCTTACAGCAGCAGCTGGCCCGCCAACAAAACCAGCAGTTACAACAGTTGCCTATGACTCAGCATCATCAGCAACAGCTAAGTGGCAACRGCTTCTCGACGGACAAACTTCTCAACAACTTTGCAGCTCCTTCGATGATGCAGTCACAACATATGCCTTCCATCCAGCCCCAGAACCAGCACAAGCCACTTACAGCAATCAGAAGCCATTCCGGTCTTACAGAAGGCGATGGTCCATCATGTTCAACTTCCCCTTCTACTAACTGCCAGATGTCCCCATCAAACTTCTTGAACAGGAATCAGCAAGGAATGGCCATGTTGTTGGGGGATTCAGTGGCCGAACCGGCTCATAATTTGGTTCAGGAGCTTCAGAGCAAGTCTGATGTTTGGGTCAAACATGAGCCGCCCAGCTCAAAAGGACCAGACCATATAAAATATAAAGGTACAATCACTGATCAGTTGGAAGCTTCATCATCTGGAACATCGTATTGTCTGGATACTAGCACAATCCATCAGAACTATGCACTTCCCACCTTCTGTTTGGATGGTGATGTTCAATCGAATCCTCGAAGCAGTCTTCCATTTTCCGCTAATATTGATGGATTGGCACCGGACACTTTGTTGTCAAGGGAATATGACTCTCAAAAAGATCTTCAGAACTTACTGTCTAATTATGGTGGGACGCCAAGAGACATTGAGACAGAGTTATCCACTGCTGCAATCAGCTCTCAGTCATTTGGGGCACCAAACATACCTTTCAAAGCTGGGTGCTCAAGTGATATTCCCATAACTGATGCTGGAGTTTTAGGCAAYGGATCGTGGGCAAACCAGGCTCAACGTATGAGAACATATACAAAGGTTCAAAAGCGTGGATCTGTGGGAAGATGCATTGATGTCAACCGTTATAAAGGCTATGATGAGCTCCGGCAWGCTCTTGCCCGCATGTTTGGGATTGAAGGGCAACTAGAAGAGCCACACAGAACGGACTGGAAACTTGTATACGTGGATCATGAAAATGAGATTCTTCTCGTTGGTGATGATCCWTGGGAGGAGTTTGTGAGCTGTGTCCAGAGTATAAAGATATTGTCATCCGTTGAAGTACAGCAGATGAGCTTGGATGGAGACCTCGGCAACATTCCAGTCCCCAATCAAGCTTCTAGCGGAACTGCCAGTGGAAATGCATGA
Protein Sequence
- >MDP0000886637
MQILDDLLIFRYPGEQKRINSELWHACAGPLVSLPPVGSLVVYFPQGHSEQVAASMQKETDLIPNYTNLPSKLICMLHNVTLHADTETDEVYAQMTLQPVNKYEKEALLASDMGLKQSRQPAEFFCKTLTASDTSTHGGFSVPRRAAEKILPPLDFSMQPPAQELVAKDLHDSAWTFRHIYRGQPKRHLLTTGWSVFVSNKRLFAGDSVLFIRDEKSQLLLGIRRAHRQQPALSSSVISSDSMHIGILAAAAHAAANNSPFTIFYNPRASPSEFVVPLAKYNKAMYTQVSLGMRFRMMFETEESGVRRYMGTVTGISDLDPVRWKGSQWRNLQVGWDESTAGDRPSRVSIWEIEPVITPFYICPPPFFRPKFPKQPGMPDDESDIDNAFRRAMPWLGDEFGMKNSPSSFFPGLSLVQWMNMQQNNQFSAAQSGFFPSMVPPTGLQNNLGTDDPSKLLSFQAPVLSSLGLQSNKSAPQNHASQMQQPNVTWAQQQQLQQLMHNPMNQQQQSNPQQQQLQQLLNSSVNQHQQNHPPQQQLQQLLNSSANQHQQNHPQQQQQLLQTPTNQQLHNFSHQQQQREPQQQQEXQNLLQHQQLHQQQPQRHQQQQLSQPNPVNNGSVAPNQVPGQNSQQPVMFSQHQQQQLLTGNTQQAVPSSSKNSFQLPTGQQNSQLQQQQLEPQPSLLQRQQQAAQLQSPPHQLLQQSVSQKVQQQPQVQQSSPQGISEQQLQLQLLQKFQQQQQPQLLSSSSSLLQPQLLQQQLARQQNQQLQQLPMTQHHQQQLSGNXFSTDKLLNNFAAPSMMQSQHMPSIQPQNQHKPLTAIRSHSGLTEGDGPSCSTSPSTNCQMSPSNFLNRNQQGMAMLLGDSVAEPAHNLVQELQSKSDVWVKHEPPSSKGPDHIKYKGTITDQLEASSSGTSYCLDTSTIHQNYALPTFCLDGDVQSNPRSSLPFSANIDGLAPDTLLSREYDSQKDLQNLLSNYGGTPRDIETELSTAAISSQSFGAPNIPFKAGCSSDIPITDAGVLGNGSWANQAQRMRTYTKVQKRGSVGRCIDVNRYKGYDELRXALARMFGIEGQLEEPHRTDWKLVYVDHENEILLVGDDPWEEFVSCVQSIKILSSVEVQQMSLDGDLGNIPVPNQASSGTASGNA*