Gene Details:

Functional Descriptions:

  • Further study showed that MdPUB23 directly interacted with MdICE1, promoting the ubiquitination-mediated degradation of the MdICE1 protein through the 26S-proteasome pathway and reducing the MdICE1-improved cold-stress tolerance in apple.
  • Our results reveal that MdPUB23 regulates the cold-stress response by directly mediating the stability of the positive regulator MdICE1.
  • MdPUB23 interacts with MdICE1, a key regulator of cold stress, and negatively regulates the cold-stress response by promoting the protein stability of MdICE1.
  • Apple U-box-type E3 ubiquitin ligase MdPUB23 reduces cold-stress tolerance by degrading the cold-stress regulatory protein MdICE1.
  • Abscisic acid insensitive 4 interacts with ICE1 and JAZ proteins to regulate ABA signaling-mediated cold tolerance in apple.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
  • >MDP0000662999
    ATGCTGCCAAGGCTGAACGGTGGTGTTTGGATGGACGACAGGGAGGACAGAGACTCTGTTTCCTGGACTAGAACCTCCGCCACCGCCACCGCCGGCAACACCGAGAACAAGGACGAGATGGGTTCTTCTCTGTCTACCTTCAARTCGATGCTGGAGGTTGAAGACGACTGGTACATGGCGGCGAATAACAGCATCCAGGGCCATTCAGATGTCGGAGACATCAGCTTCTCGCCGAGCTTTGCCGACCCAGAAAGCTTGCTGCTCAACCCGGTGGACTCTTCCTCCTCCTGCTCACCGTCGTCGTCGGTTTTCAACAATCTCGACCCGAATCAGGTTCATTACTACATGCCTCAAAATCCCAACTTGTCTTCGCTGCTTAATGTTGTTCCTAACAACCCTTTGGATCACGGCTTCGATTTGGGCTGTGACATTGGGTTTCTTGACACTCAAGCTTCGGGTGGCGGTTCGAGTATGATGAACAGGGGAGGTGGGGTTTTATCTGGATTCAATGATTTAAGCTCGAATAGCCAGGTGAATGCTCAGAATTTGGGTTCTAATTTACAGTTTTCGACTACCCGCATGCCTCAAGCTCTTGAAAACAGTTCAAATTTTTCGGGTTTTCGAGGTGTGGATGATGGTTCGGCAAATGCTTTGTTTCCCAATAGGCCTAAGTTACTGAGACCACTTGAATCCTTCCCTTCTGTGGGAGTCCAGCCAACTCTTTTCCAGAAAAGAGCAGCGCTTCGGAAAAACTTAGGCGATGGTGGAGGGAATTTGGGTGTTTTGGKCTCACAAGGGGGCCTGGTTTTGAATGAAGGGGATGAGAGGAAGAGGGAGATGGGTGTGCAGAATGAGAAGAAGAGGAAAATGAGCGGCGSMGATGATGTCGATGATCTGAGTTTCGATGGTTCGGGTTTGAACTATGATTCGGATGAGTTTACTGAGAACACTAAGGTTGATGACGGTGCCAAGAATGGTGGGAACAGCTCGAATGCAAATAGCACKGTTACCGGTGGAGGAGGGGGTCATAAGGGGAAGAAGAAAGGGTTGCCTGCCAAGAATCTGATGGCTGAGAGGCGCCGCCGGAAGAAGCTCAATGATAGGCTGTACATGCTGAGATCCGTTGTTCCGAAGATTAGCAAAATGGACAGGGCCTCAATCCTTGGGGATGCAATTGAGTACTTGAAGGAACTTCTGCAGAGGATCAACAACCTCCACAATGAACTGGAGTCAATCCCTCCTGGATCTGCATTGACACCTACCGGAAATACTTTCCACCCTTTGACACCCACTCCGGCTACTCTGCCAAATCGTATCAAGGAAGAACTTTGCCCCAGCTCATTACCTAGCCCAAATGGCCAAGCTGCAAGGGTTGAAGTTAGGCTGCGAGAAGGACGAGCAGTTAACATCCACATGTTCTGCGGCCGAAGGCCAGGTCTCTTGCTCTCAACCATGAGAACTTTGGATAACCTTGGGTTAGACATCCAGCAAGCCGTCATCAGCTGTTTCAATGGTTTTGCTATGGATGTCTTCCGTGCCGAGCAATGCAAGGAAGGCCAAGACGTCCACCCGGATCAGATAAAGGCGGTACTTCTGGATTCGATCGGGTTCCATGGCATGATGTAG
Protein Sequence
  • >MDP0000662999
    MLPRLNGGVWMDDREDRDSVSWTRTSATATAGNTENKDEMGSSLSTFKSMLEVEDDWYMAANNSIQGHSDVGDISFSPSFADPESLLLNPVDSSSSCSPSSSVFNNLDPNQVHYYMPQNPNLSSLLNVVPNNPLDHGFDLGCDIGFLDTQASGGGSSMMNRGGGVLSGFNDLSSNSQVNAQNLGSNLQFSTTRMPQALENSSNFSGFRGVDDGSANALFPNRPKLLRPLESFPSVGVQPTLFQKRAALRKNLGDGGGNLGVLXSQGGLVLNEGDERKREMGVQNEKKRKMSGXDDVDDLSFDGSGLNYDSDEFTENTKVDDGAKNGGNSSNANSTVTGGGGGHKGKKKGLPAKNLMAERRRRKKLNDRLYMLRSVVPKISKMDRASILGDAIEYLKELLQRINNLHNELESIPPGSALTPTGNTFHPLTPTPATLPNRIKEELCPSSLPSPNGQAARVEVRLREGRAVNIHMFCGRRPGLLLSTMRTLDNLGLDIQQAVISCFNGFAMDVFRAEQCKEGQDVHPDQIKAVLLDSIGFHGMM*