MdMYB21

Gene Details:

MdMYB21 was significantly associated with fruit malic acid content, accounting for ~7.48% of the observed phenotypic variation in the apple germplasm collection.
Analyses of transgenic apple calli, fruits and tomatoes demonstrated that MdMYB21 negatively regulated malic acid accumulation.
MdMYB21 directly binds to the MdMa1 promoter and represses its expression. Interestingly, a 2-bp variation in the MdMYB21 promoter region altered its expression and regulation of its target gene, MdMa1, expression.
The results showed that MdMYB21 negatively regulates malic acid accumulation by directly binding to the promoter of MdMa1 and repressing its expression, resulting in decreased apple acidity.

cDNA Sequence

CDS Sequence

>MDP0000659260
ATGGCTGCTCCTACAACCCCAAATGAAGAAAATGAGTTCAGAAGAGGGCCATGGACTCTTGAGGAAGACAATCTGCTTATACATTACATCGTGAACCACGGCGAAGGCCATTGGAATTCTKTAGCAAAACTTGCAGGATTGAAGAGGACCGGAAAAAGCTGCAGATTGAGATGGCTAAATTACTTAAAACCCGACATTAAGCGCGGGAACCTTACTCCGCAAGAACAGCTCATGATCCTTGAACTCCACTCCAAGTGGGGTAACAGGTGGTCTAAAATTGCGCAGCATTTGCCGGGAAGAACAGACAATGAGATAAAGAACTATTGGAGAACAAGGGTGCAAAAACAGGCGCGCCAACTGAACATCGAGTCGAACAGCGAGCAATTTCTCGATGCAGTTCGGGGTTTCTGGGTGCCGACTCTGCTGCAAAAAATGGAGCAATCTTCTTCTTCTTGTTCTTCAACCTTGAGCACTTCTCAGAACTCCGCATCTCCTTGTCTGTCACCAAATCACGCAGCTCCTTCCGTGCCACTCTCAACCTCTCCACCTAGCAATGCGACAAACGTGTTGGACAATTATCACATTAGTGGAAATTCCAATCTTGCCACCGTCCCAAGTAATATCCTTTCGGCGGATTCTTTTGTTTCACACGTGCCTCAAATGGCAGAACCGTCCACGAGTTTTCCCCCTGCATATTACCGACTTGGCTACAGCAGCTTAAGTCCAGATGGCAGTCACTACGTGGACAGCAGTAGCTATGACGTGGAGGGTCTCAGCCTGGACCCTGTTTCGGCAATGGGCAATCTTGGCAATTCACAGTTTGATTGCCAGATGGGGGGAAATGATTGGATGTTGGACAATGTGACTGACAGTTTATGGAACATGGATGGGCCGTGA

Protein Sequence

>MDP0000659260
MAAPTTPNEENEFRRGPWTLEEDNLLIHYIVNHGEGHWNSXAKLAGLKRTGKSCRLRWLNYLKPDIKRGNLTPQEQLMILELHSKWGNRWSKIAQHLPGRTDNEIKNYWRTRVQKQARQLNIESNSEQFLDAVRGFWVPTLLQKMEQSSSSCSSTLSTSQNSASPCLSPNHAAPSVPLSTSPPSNATNVLDNYHISGNSNLATVPSNILSADSFVSHVPQMAEPSTSFPPAYYRLGYSSLSPDGSHYVDSSSYDVEGLSLDPVSAMGNLGNSQFDCQMGGNDWMLDNVTDSLWNMDGP*