Gene Details:

• Gene ID: MDP0000643281
• Gene Symbol: MdBT2
• Gene Name: BROAD-COMPLEX, TRAMTRACK AND BRIC A BRAC2
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• MdBT2 is a BTB protein that directly interacts with and stabilizes MdCOP1 by inhibiting self-ubiquitination.
• MdBT2 interacted with MdCOP1 and promoted MdCOP1 accumulation in the nucleus.
• A series of phenotypic analyses indicated that MdBT2 promoted MdCOP1-mediated ubiquitination and degradation of the MdMYB1 transcription factor, inhibiting the expression of anthocyanin biosynthesis genes and anthocyanin accumulation.
• Our findings reveal a molecular mechanism by which MdBT2 positively regulates MdCOP1, providing insight into MdCOP1-mediated anthocyanin biosynthesis.
• The BTB protein MdBT2 recruits auxin signaling components to regulate adventitious root formation in apple.
• MdBT2 acts as a negative regulator of AR formation in apple.
• The apple MdCOP1-interacting protein 1 negatively regulates hypocotyl elongation and anthocyanin biosynthesis.

Function-related keywords:

• transcription-factor ,  root ,  auxin ,  nucleus ,  root-elongation ,  auxin-biosynthesis ,  adventitious-root ,  transcription-regulator ,  adventitious-root-formation ,  anthocyanin-biosynthesis ,  anthocyanin ,  protein

Literature:

• The apple BTB protein MdBT2 positively regulates MdCOP1 abundance to repress anthocyanin biosynthesis.   DOI:  10.1093/plphys/kiac279 ;  PMID:  35674376
• The BTB protein MdBT2 recruits auxin signaling components to regulate adventitious root formation in apple.   DOI:  10.1093/plphys/kiac084 ;  PMID:  35218363

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: