Gene Details:

Functional Descriptions:

  • Ethylene precisely regulates anthocyanin synthesis in apple via a module comprising MdEIL1, MdMYB1, and MdMYB17.
  • MdMYB17 binds directly to the promoters of the ethylene-induced genes MdMYB1 and MdEIL1, which encode positive regulators of anthocyanin synthesis, and represses their expression.
  • MdEIL1, which is a critical component of the ethylene signaling pathway, binds directly to the MdMYB1 promoter to induce expression, which in turn promotes anthocyanin accumulation and fruit coloration.
  • Overall, our results reveal the molecular mechanisms by which MdMYB17, MdMYB1, and MdEIL1 finely mediate ethylene-regulated anthocyanin synthesis in apple fruit.
  • EIN3-LIKE1, MYB1, and ETHYLENE RESPONSE FACTOR3 Act in a Regulatory Loop That Synergistically Modulates Ethylene Biosynthesis and Anthocyanin Accumulation.
  • MdEIL1 directly bound to the promoter of MdMYB1 and transcriptionally activated its expression, which resulted in anthocyanin biosynthesis and fruit coloration.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
  • >MDP0000423881
    ATGGTGATCTTTGAGGAGTTAGGTTTCTCTGGTAATCTTGACTATCTTTTGGCTCCATCTGGGRAAGGGGATGCAGCTCCAGAACATGAACAAGAGGCAACTGTGGAGGAGGATTATAGTGATGAAGAAATGGATGTTGATGAGCTYGAGAAGAGGATGTGGAGAGATCGAATGCTACTGAAGARGCTGAAAGAACAAACTAAGGGAAAGGAAGGAGTTGACAATGCAAGACAGCGTCAATCACAGGAACAAGCGCGGAGGAAGAAGATGTCACGGGCACAAGATGGAATCCTGAAATATATGCTGAAAATGATGGAAGTTTGCAAAGCTCAGGGTTTTGTTTATGGRATTATCCCTGAAAAAGGAAAACCAGTGAGTGGCGCCTCTGACAATCTGCGAGCATGGTGGAAGGAAAAAGTAAGATTTGATCGTAATGGCCCGGCTGCGATTTCTAAGTATCAGGCAGATCATTCAATCCCTGGGAAGAATGAAGACTTCAGTGCAGTGGCATCCACTCCTCACACCTTACAGGAGCTCCAAGAYACCACTCTTGGTTCACTTTTGTCAGCTTTGATGCAGCACTGCAATCCACCCCAAAGACGTTTCCCGTTGGAGAAGGGTGTTGCTCCTCCTTGGTGGCCTACTGGTAACGAGGAATGGTGGCCKCAACTAAATCTYCCCCAGGATCAGTGTCCTCCCCCATACAAGAAGCCTCATGATCTGAAGAAGGCTTGGAAGGTTGGTGTTCTCACGGCTGTGATTAAGCACATGTCRCCAGATATTGCAAAGATCCGCAAGCTTGTTCGTCAGTCCAAATGTTTGCAGGACAAAATGACTGCTAAGGAGAGCGCCACTTGGCTAGCCATTATAAACCAGGAGGAAGCTYTGGCCCGGAGGCTATATCCTGATAGATGTCCACCTCCATTTGCTGGTGGGAGTGAGTCTCTCGCAATCAGTGGTACTAGTGATTATGATGTYGAAGGGGTTGATGATGACGAAAATGTTGAAATAGAGGATTGCAAACCTCTTGTTAATCACTTCAWCATTGGAGCGACTGGACAAAGAGAGAGGCAGGTGGTACCTCAGGTTAAGGGAGAGCWCATCGAGATCAACTCGGATTTTGGTCCGAAGAGGAAGCAGCTGGCTGAAGAGCCACAAATGATGTTAGATCAGAAGTATTACGCCTGCGAATATCTGCAGTGCCCGTATCATGATTATCGCCTAGGCTTTCTCGACATAACTGCAAGAAACAATCATCAGTTGAATTGTCCATACCGGAATAATTCTTCACAAGTTCTGGGAATGTCAAGCTTTCAGCTTCACAATGAGAAACCTGTGGACTTCTCTCTACCCATTGCTCAACCACCAACACCAGCAATTCAACGACCAGTGAACCAGTCAAGTGGGTTTGATGCTTTGGGACTTGGAAATCAACAGCAGGTGAAYCAATCAAGTAGGTTCGATGCTTCGGGACTTGGAAATCAACAGCAGGTGAACCAGTCAAATAGGTTYGATGCTTCGAGAATTGGAATTCAACAACCAGTGAACCAGTCAGGTAGGTTTGAYTCTTCGGGGCTTGGAATTGCTGAGGATGGGCAGAAAATGATATCCGAGCTTATGTCATTCTATGATAGTAATATACAGCAAAACAAGAACTGCAATCCTGGAAACCTAAATGATGTAGATGATTGCAATCAGCAGCAGGCTAACTTTCAATTTCCAATGAATGATAACTTATRTGGTCAAGGGCTGGACATAGGACGCAACATGAACATGTCGGAACAGTCCCCMATGCCTATGCTTCATCCAGATTTTTCATCCCCGGAAGTTCAGTTTGATCARTTGATGGCATTTGATTCTCCATTTGGTAACAATTCCAACGAAGATGTCGACATAAGATTTGGCTCCCCCTTGCACTTGTCACCTGTTGGTTATAATGTTATGGACCCGCCTCTGAACCAAGACCCCTGGTTCCCATGA
Protein Sequence
  • >MDP0000423881
    MVIFEELGFSGNLDYLLAPSGXGDAAPEHEQEATVEEDYSDEEMDVDELEKRMWRDRMLLKXLKEQTKGKEGVDNARQRQSQEQARRKKMSRAQDGILKYMLKMMEVCKAQGFVYGIIPEKGKPVSGASDNLRAWWKEKVRFDRNGPAAISKYQADHSIPGKNEDFSAVASTPHTLQELQDTTLGSLLSALMQHCNPPQRRFPLEKGVAPPWWPTGNEEWWPQLNLPQDQCPPPYKKPHDLKKAWKVGVLTAVIKHMSPDIAKIRKLVRQSKCLQDKMTAKESATWLAIINQEEAXARRLYPDRCPPPFAGGSESLAISGTSDYDVEGVDDDENVEIEDCKPLVNHFXIGATGQRERQVVPQVKGEXIEINSDFGPKRKQLAEEPQMMLDQKYYACEYLQCPYHDYRLGFLDITARNNHQLNCPYRNNSSQVLGMSSFQLHNEKPVDFSLPIAQPPTPAIQRPVNQSSGFDALGLGNQQQVNQSSRFDASGLGNQQQVNQSNRFDASRIGIQQPVNQSGRFDSSGLGIAEDGQKMISELMSFYDSNIQQNKNCNPGNLNDVDDCNQQQANFQFPMNDNLXGQGLDIGRNMNMSEQSPMPMLHPDFSSPEVQFDQLMAFDSPFGNNSNEDVDIRFGSPLHLSPVGYNVMDPPLNQDPWFP*